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biotech commercialization Archives - BioHealth Innovation

BHI EIR Insights: We’ve Seen Something Like This Before: Agentic AI and the Early Days of Online Research

By EIR Insights, News

This thought-provoking piece in The Wall Street Journal (“Can AI Replace Humans for Market Research?”) by Belle L. (Lin) highlights the use of AI agents for ✅ opinion polling and ✏ market research. The article made me think of another time when new technology offered the potential to create value through digital transformation in this sector.

At the height of the dot com era, c. 1999, I was asked by Jeremy Brody to co-found one of the first-ever online research firms. The idea that technology makes work “faster, cheaper, AND easier” was appealing, especially coming from consulting early in our careers.

Along with our small, all-star team, stellar board, and a few partners, our leverage for growth was a web-based survey app and an opt-in doctor database. At the time, these assets were disruptive.

Our work helped move research from fax (yes, fax! 📠), mail, and phone to a Web-based digital platform đŸ€–.

The surveys focused on topics like:

âžĄïž Unmet medical needs,
âžĄïž New product features and functionality,
âžĄïž Evidence generation, and
âžĄïž Launch strategy.

These topics remain a big portion of the $150 billion insights industry today (for market size, see article link below).

When we built that early dot com research agency, the American Medical Association’s latest data (1997) said only 20% of physicians were using the Internet. By 2000, it nearly doubled to 37%. So we had to help build the market as adoption caught up to the technology’s capabilities.

Adoption of AI is much faster.

Whether in research or other domains, the discussion and the decisions (in my opinion) need to focus on appropriate use cases, governance, and ethical use. What’s your take?

💡 For what specific business need would you use agentic market research?

💡 In what situations would you be reluctant or avoid it?

Thanks to Belle Lin for the excellent article 💯 . Here is the link: https://lnkd.in/eKUNx-W9

BioHealth Innovation Welcomes Dr. Nilay Shah to Board of Directors

By News

BioHealth Innovation, Inc. (BHI) is pleased to announce the appointment of Dr. Nilay Shah to its Board of Directors. A physician–executive with more than 20 years of experience in global clinical development and commercial strategy, Dr. Shah brings deep expertise in advancing innovative therapies from early development through regulatory approval and market entry.

Dr. Shah currently serves as Senior Vice President and Global Head of Ophthalmology at Emmes, where he leads the company’s fastest-growing therapeutic division and serves on the Executive Management Committee. Over the course of his tenure, he has helped scale the organization into a global CRO serving biotech innovators across North America, Europe, Latin America, and Asia. His experience spans Phase I through Phase III trials, FDA and EMA engagement, pharmacovigilance, and strategic alliances with emerging and growth-stage life sciences companies.

Throughout his career, Dr. Shah has served as a Medical Monitor for various studies and also has directed complex, multi-national clinical programs, including global trials supporting market authorization of novel biologics and the first autonomous AI-based diagnostic system approved by the FDA for the detection of diabetic retinopathy. He has also built and led high-performing cross-functional teams, strengthened commercial strategy, and partnered closely with venture-backed companies navigating regulatory and operational milestones.

Beyond his executive leadership, Dr. Shah has played an active role in Maryland’s innovation ecosystem. He serves as an advisor and reviewer for multiple TEDCO venture programs and is a Board Member of the Baltimore Innovation Initiative, where he supports early-stage founders in clinical strategy, regulatory planning, and commercialization.

“Nilay brings a rare combination of physician insight, global clinical operations leadership, and commercial acumen,” said BHI President and CEO, Rich Bendis. “He understands what it takes to move a therapy from concept to approval, and he has done it at scale. As we continue to support entrepreneurs and growing companies across the BioHealth Capital Region and beyond, his experience will strengthen our ability to guide companies through critical development and regulatory inflection points.”

“I am honored to join the Board of BioHealth Innovation at a pivotal time for the BioHealth Capital Region,” said Nilay C. Shah, MBBS (MD), Senior Vice President and Global Head of Ophthalmology at Emmes. “We are witnessing a powerful convergence of breakthrough science, artificial intelligence, and precision medicine, but innovation only matters if it translates into approved and accessible therapies. Throughout my career in global clinical development, I have seen how early strategic guidance and disciplined execution accelerate that journey. BioHealth Innovation uniquely bridges scientific innovation and commercialization, and I look forward to supporting entrepreneurs as they navigate critical regulatory and development milestones to bring transformative therapies to patients faster.”

Dr. Shah’s appointment reflects BHI’s continued focus on assembling a board with hands-on experience in therapeutic development, regulatory strategy, venture engagement, and global operations. His perspective will support the organization’s mission to accelerate commercialization, mentor emerging companies, and expand the region’s leadership in biohealth innovation.

BHI EIR Insights: 7 Tactics to Optimize Launch Messaging – Part VI

By EIR Insights, News

by Jonathan Kay, MPP, Managing Partner, Health Market Experts & BioHealth Innovation, Inc. Entrepreneur-in-Residence

As we conclude our Optimizing Launch Messaging series, we’ve explored how to create clear, targeted, and evidence-based messages. For our final insight, we’re focusing on a tool that’s rapidly changing the communication landscape: artificial intelligence. We’ll focus on generative AI here, and similar lessons can apply to agentic AI down the road.

Insight 7: Engage the power of AI in message optimization

When preparing for launch (or really any high-stakes communication) the strongest messages come from a partnership between humans and AI. Here’s the workflow we recommend:

A. Workshop the message development 🧠

Bring your teams together early to outline goals, target audiences, and the strategic backbone of your message.

B. Invite AI to that workshop đŸ€–

Use AI to generate message concepts, explore angles you may have neglected, and broaden strategic and creative possibilities. Three years ago, I wrote an article about inviting AI to the clinical care team. That’s happening more and more. Similarly, we should invite AI to our consulting workflows.

C. Refine the messages with humans đŸ‘„

Review AI-generated ideas with expert oversight to ensure accuracy, nuance, and alignment with your strategic intent.

D. Test the messages with real stakeholders 🔍

Interview stakeholders to find out how the test messages land. Focus on audiences that will make or break your launch. That could be physicians, payer decision makers, patients and their advocates, hospital executives and more.

E. Refine again before deployment 🎯

Integrate testing feedback to sharpen language, strengthen relevance, and remove confusing or misaligned elements.

F. Build in a post-launch feedback loop 🔁

See our earlier post Tactic #5 about defining and measuring success to evaluate the impact of your message, and inform your future communications.

Recently, Health Market Experts, LLC teamed up with Oakton Communications Partners and Sequencr AI for a series of webinars showcasing our point of view on the power of human + AI collaboration in message optimization for issues and crisis management. Our methods for GTM message optimization were applicable in the context of issues and crisis management, too.

Have you used AI in your messaging work? 💬 What worked well for you?

DM me if you’re interested in learning more about our point of view or engaging in one of our workshops.

If your organization is preparing to launch a new business or brand, connect with us (message me on LinkedIn) or visit https://www.healthmarketexperts.com/ to learn more about how we can help you with messaging and commercial strategy to set your business and brand on a path of success.

Written by a human. This post expands on content I previously wrote as a blog at Catalant and delivered in guest lectures at Rutgers Business School.

Visit https://www.linkedin.com/in/jonathan-kay-healthcare/ to connect with Jon on LinkedIn.

BHI EIR Insights: 7 Tactics to Optimize Launch Messaging – Part VI

By EIR Insights, News

by Jonathan Kay, MPP, Managing Partner, Health Market Experts & BioHealth Innovation, Inc. Entrepreneur-in-Residence

To recap, the first 5 posts of our series covered:

  1. Test, Don’t Guess: Adopt a data-driven mindset about messaging impact
  2. Know Your Stakeholders: Avoid a one-size-fits-all approach
  3. Listen First: What are  your stakeholders saying and how?
  4. Message Anatomy: Ensure messages get the job done
  5. Measuring Success: Define metrics of success upfront

Insight 6: Just Start

It’s true we want to pursue all 5 tactics above. But that doesn’t mean we always can.  Sometimes clients or would-be clients insist:

  • Time is too limited, so they can’t test
  • The target audience is rare or ultra rare, so they can’t test

🛑 Hold on! Don’t skip testing even in these situations. As the saying goes, Don’t let perfect be the enemy of the good.(That’s typically attributed to surgeons!đŸ„Œ)

Real-world problems require real-world problem-solving. To know in advance how well your messages will perform, ask real-world stakeholders. Even if time is extremely limited. Even if audiences seem too hard-to-reach. (We can help you in both cases. While we encourage clients to have a launch runway and notify us in advance, typically we can line up test audiences in a day or two, or faster!)

Testing messages BEFORE launch can improve early uptake 📈, increase commercial success, and save time and budget later. It can help you avoid unnecessary stress.

✅ Rather than skip testing, “just start” testing by modifying the ideal and going with what is realistic. Here are a few ideas:

  • Fewer interviews
  • Shorter survey
  • Leverage Gen AI (more to come in Tactic #7)
  • Plan ahead: put message testing in your launch plan

When a client was preparing to launch a genetic marker for a rare disease, they approached us to test physician ad concepts and messages. They faced two familiar constraints in biotech launches:

  1. Limited time
  2. A small, hard-to-reach physician population

One more traditional approach might have been to test messages → share feedback with client and creative agency → agency modifies concepts → ideally we test again to optimize. Instead, we compressed the process and reduced the timeline by days, possibly a week. (How great would it be to save a week when getting ready for launch?)

How did we do that?

  • We reduced the number of stakeholder interviews.
  • We prioritized metrics like stopping power, visceral response, clinical credibility
  • Importantly, we invited the agency into the testing process.

Bringing the agency in allowed for agile development. As the interviews progressed, the concepts evolved, and we moved closer and closer to optimal with each next test.

The results were telling, actionable, and valuable even with a small sample. We confirmed a key hypothesis, which added confidence to the commercial strategy. We also revealed confusing language about the biomarker that we easily fixed to avoid encountering post-launch confusion, questions, and delayed product adoption.

The key takeaway: When launching a business or a brand or a campaign, perfect conditions are rare. But even limited testing can uncover powerful insights, reduce risk, and strengthen confidence before your message reaches the market.

If your organization is preparing to launch a new business or brand, connect with us (message me on LinkedIn) or visit https://www.healthmarketexperts.com/ to learn more about how we can help you with messaging and commercial strategy to set your business and brand on a path of success.

Written by a human. This post expands on content I previously wrote as a blog at Catalant and delivered in guest lectures at Rutgers Business School.

Visit https://www.linkedin.com/in/jonathan-kay-healthcare/ to connect with Jon on LinkedIn.

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