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SBIR and the Phase III Challenge of Commercialization

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Small businesses are a major driver of high-technology innovation and economic growth in the United States, generating significant employment, new markets, and high-growth industries.1 In this era of globalization, optimizing the ability of small businesses to develop and commercialize new products is essential for U.S. competitiveness and national security. Developing better incentives to spur innovative ideas, technologies, and products—and ultimately to bring them to market—is thus a central policy challenge.

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NIAID/GSK experimental Ebola vaccine appears safe, prompts immune response

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An experimental vaccine to prevent Ebola virus disease was well-tolerated and produced immune system responses in all 20 healthy adults who received it in a Phase 1 clinical trial conducted by researchers from the National Institutes of Health. The candidate vaccine, which was co-developed by the NIH’s National Institute of Allergy and Infectious Diseases (NIAID) and GlaxoSmithKline (GSK), was tested at the NIH Clinical Center in Bethesda, Maryland. The interim results are reported online in advance of print in the New England Journal of Medicine.

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NHLBI Funding & Research Opportunities and Announcements for November 25, 2014

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Funding and Research Opportunities

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:
Notices:

  • NIH Implementation of the US Government Policy on Institutional Oversight of Life Sciences Dual Use Research of Concern
  • Publication of Notice of Proposed Rulemaking for Clinical Trials Registration and Results Submission under FDAAA
  • NIH Request for Public Comments on the Draft NIH Policy on Dissemination of NIH-Funded Clinical Trial Information
  • Request for Information (RFI): Inviting Comments and Suggestions on the Reagent-Related Barriers to Reproducible Research
  • Reminder: Annual Reports to the Office of Laboratory Animal Welfare due January 31, 2015
  • Notice of Intent to Publish a Funding Opportunity Announcement for Sudden Death in the Young: Population-Based Studies (U01)

Program Announcements

  • Systems Science and Health in the Behavioral and Social Sciences (R21)
    • (PAR-15-047
    • Office of Behavioral and Social Science Research
    • National Cancer Institute
    • National Institute on Aging
    • National Institute on Alcohol Abuse and Alcoholism
    • National Institute of Biomedical Imaging and Bioengineering
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development 
    • National Institute of Dental and Craniofacial Research
    • National Institute of Environmental Health Sciences
    • National Institute of Mental Health
    • National Institute of Nursing Research
    • Office of Disease Prevention
    • Application Receipt/Submission Date(s): Multiple dates, see announcement.
  • Systems Science and Health in the Behavioral and Social Sciences (R01)
    • (PAR-15-048
    • Office of Behavioral and Social Science Research
    • National Cancer Institute
    • National Institute on Aging
    • National Institute on Alcohol Abuse and Alcoholism
    • National Institute of Biomedical Imaging and Bioengineering
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development 
    • National Institute of Dental and Craniofacial Research
    • National Institute of Environmental Health Sciences
    • National Institute of Mental Health
    • National Institute of Nursing Research
    • Office of Disease Prevention
    • Application Receipt/Submission Date(s): Multiple dates, see announcement.
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Top 10 health IT predictions for 2015 – Healthcare IT News

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In 2015, hospitals will – and should – make more advanced use of “third platform” technologies based on mobile tools, social channels, data analytics and the cloud, according to a recent report from IDC Health Insights.

With healthcare costs unsustainable, but these new technologies now ubiquitous, IDC officials say hospital CIOs will increasingly be turning to new tools – especially as consumers expect healthcare to be as responsive to their wants and needs as other industries.

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New SBIR Opportunities: Why Phase III Contractors And Venture Capital Companies Should Consider Possible Changes To The SBIR And STTR Programs – Government, Public Sector – United States

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Any small business or venture capital company interested in Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) funding opportunities should pay close attention to the Small Business Administration’s (SBA) recent request for public comments, by January 6, 2015, on data rights and Phase III funding, and a recent Government Accountability Office (GAO) report identifying the National Institutes of Health (NIH) and Department of Energy’s Advanced Research Projects Agency-Energy (ARPA-E) as the two agencies presently accepting applications from majority-owned portfolio companies.

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Maryland’s finding a future in 3-D (Video) – Baltimore Business Journal

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Lacrosse sticks, construction models and surgical tools — these are all things Baltimore companies are making with the help of 3-D printing.

Three-dimensional printing was invented decades ago but has really taken off in the last few years. Printers are more affordable (you can get one for your desktop for the price of a MacBook Pro). And printing material has advanced significantly, to include more durable plastics, metal and more.

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