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AstraZeneca – MedImmune enters licensing agreement with Omnis Pharmaceuticals for oncolytic viruses in immuno-oncology

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AstraZeneca today announced that MedImmune, its global biologics research and development arm, has entered into a licensing agreement with Omnis Pharmaceuticals (Omnis), a privately-held biotechnology company focused on the development of oncolytic viruses. This agreement will allow MedImmune to combine key agents from its investigational immunotherapy portfolio with Omnis’ lead investigational oncolytic virus programme, a genetically engineered strain of vesicular stomatitis virus (VSV). The programme is currently being studied in a Phase I clinical trial as a monotherapy for the treatment of hepatocellular carcinoma and other cancers that have metastasised to the liver.

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Roche to Buy Majority Stake in Foundation Medicine, Leader in Tumor Testing – NYTimes.com

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The Swiss pharmaceutical giant Roche said on Monday that it would acquire a majority stake in the tumor-testing company Foundation Medicine for more than $1 billion, in a deal aimed at improving both cancer treatment and drug development.

Foundation is the leader in the growing area of sequencing the genes of tumor samples, looking for mutations that can help predict which drug will be most effective for a particular patient.

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Roche Spends $1.03 Billion For Majority Stake In Foundation Medicine

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Roche, the world’s largest maker of cancer drugs, is spending $1.03 billion to buy a 56.3% stake in Cambridge, Mass.-based Foundation Medicine, a company that uses genetics to help select drugs for cancer patients. Roche, based in Basel, Switzerland, will also market Foundation’s diagnostic tests outside the U.S., help educate doctors as to the value of the tests in the U.S., and provide another $150 million to support additional research on Foundation’s products.

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Vivek Wadhwa: How Technology Will Eat Medicine – The Accelerators – WSJ

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The most significant announcement that Apple made in 2014 wasn’t a larger-sized iPhone. It was that Apple is entering the health-care industry. With HealthKit, it is building an iTunes-like platform for health; Apple Watch is its first medical device. Apple is, however, two steps behind Google, IBM and hundreds of startups. They realized much earlier that medicine is becoming an information technology and that the trillion-dollar health-care market is ripe for disruption.

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Baltimore bioscience firm PathSensors gets $500K investment to expand in China – Baltimore Business Journal

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Balitmore’s PathSensors Inc. has received $500,000 from a Chinese investor to expand the bioscience company’s footprint in China.

The private investor, Michael Song, is president of Shanghai Qi Fa Electronics Co. Ltd. in China. The money will allow PathSensors to grow sales of its surface and airborne detection systems in China. Funding will also go toward market expansion in the U.S.

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GBC will push for angel investor tax credit in 2015 – Baltimore Business Journal

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Greater Baltimore Committee wants legislators to establish a state tax credit for angel investors who support early-stage companies.

Legislation to create the tax credit will be a top priority for the business advocacy group during the upcoming General Assembly session. The organization will also push for programs to create more on-the-job training opportunities for students. Priorities also include strengthening science and technology education in grade school and securing funding for transportation infrastructure.

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Want to help Ebola research? Rockville company makes pitch for clinical trial volunteers – Washington Business Journal

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Rockville-based contract research firm Optimal Research announced it will begin clinical trials this month for the Johnson & Johnson (NYSE: JNJ) Ebola vaccine, considered one of the frontrunners in the race to address the Ebola crisis.

Optimal Research Chief Operating Officer E.B. McLindon said Friday the company is seeking individuals to participate in a Phase I Clinical trial for the vaccine. The company plans to administer the vaccine to 92 healthy volunteers in January and February to determine its safety.

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