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NHLBI Funding & Research Opportunities and Announcements for March 31, 2015

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Funding and Research Opportunities

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:

Notices: 

  • Request for Information (RFI): NHLBI Strategic Visioning – Developing the Research Priorities for the Next Decade
  • Notice of Change to Award Information Regarding Allowable Requested Direct Costs in PAR-13-316 “NHLBI Program Project Applications (P01)” 
  • Notice of National Heart, Lung, and Blood Institute (NHLBI) Participation in PAR-15-085 “Predictive Multiscale Models for Biomedical, Biological, Behavioral, Environmental and Clinical Research (U01)” 

Requests for Applications:

  • Genome Sequencing Program Coordinating Center (U24)
    • (RFA-HG-15-019)
    • 
National Human Genome Research Institute
Application Receipt Date(s): May 29, 2015
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Immunomic Therapeutics, Inc. Awarded SBIR Grant From NIH for Nanoplasmid Peanut Allergy Vaccine Development

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Immunomic Therapeutics, Inc. (“ITI”), a privately-held biotechnology company developing vaccines based on its proprietary LAMP technology, today announces that the National Institutes of Health has awarded ITI’s Small Business Innovation Research (SBIR) grant application titled, “Development of Nanoplasmid LAMP-based Peanut Allergy Immunotherapy.” The work in this award will help the pre-clinical development of new and advanced therapeutic platforms for peanut allergies.

“The receipt of this grant provides validation and financial support to evaluate the innovative combination of MHC-II targeting of important peanut allergens delivered in a minimal plasmid DNA backbone. With NIH’s support, we look forward to designing and evaluating new plasmid-based constructs for their immunological activity and improved safety profile, which builds off of ITI’s considerable expertise in plasmid-based therapeutics for food allergies. This research has the potential to help the more than one million Americans who suffer from peanut allergies,” said Teri Heiland, Ph.D., Vice President of R&D, ITI.

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HHS CTO Sivak leaving government in April

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Chief technology officer at Health and Human Services, Bryan Sivak, is leaving the agency and retiring from federal government at the end of April, according to a department memo.

During his four years at the agency, Sivak was an ardent proponent of using technology to innovate and provide better services, both for the civilians the agency serves and for the employees internally.

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MedImmune, BioHealth Innovation Inc., and Tech Council of Maryland chart path for region’s biotech community – Washington Business Journal

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Could Greater Washington be one of the big three in biotech beside other market leaders like, say, Boston?

That was certainly the rallying cry Monday as CEOs and a few hundred entrepreneurs, academics and government types packed into MedImmune’s auditorium in Gaithersburg. MedImmune, the research and development arm of AstraZeneca (NYSE: AZN), was hosting the first Maryland Regional Biotech Forum to chart a course for elevating the region’s reputation into the top three by 2023. The event was also hosted by the Tech Council of Maryland and BioHealth Innovation Inc.

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Joel Marcus of Alexandria Real Estate on the Biotech Boom – Venture Capital Dispatch – WSJ

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Biopharmaceutical venture capital investment climbed from $4.52 billion in 2013 to $5.29 billion in 2014, a 17% increase, according to Dow Jones VentureSource.

Joel Marcus, chief executive of Alexandria Real Estate Equities Inc., has been in biotech since its early days. From 1984 to 1994, he had a law career with expertise in the biopharmaceutical industry that included time as general counsel and secretary of Kirin-Amgen Inc., a joint venture between Kirin Brewery Co. and Amgen Inc.

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Top 10 states project profile: Qiagen’s North American Corporate Headquarters – U.S. Green Building Council

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Maryland is no stranger to USGBC’s Top 10 States for LEED list, and every year it has a strong list of impressive LEED projects certifying across the state. Maryland was the third state in the nation for LEED in 2014 (2.7 square-feet of LEED certified space per resident) based on the strength of its 132 newly certified projects.

One project that stands out this year is Qiagen’s new North America headquarters building, which is important not only because of its impressive architecture, but also because of the building’s purpose and what projects like this one symbolize about the growing impact of the green building movement across the country. Qiagen uses its 66,735 square foot headquarters for new research in the field biotechnology as well as its North American manufacturing operations. Skanska USA, a Platinum level member of USGBC, served as the contractor on the Qiagen project, ushering the building toward LEED certification.

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Pieris Pharmaceuticals and The University of Melbourne Receive Research Grant to Advance Immunological Diseases Program

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Pieris Pharmaceuticals, Inc. (OTCQB: PIRS)and The University of Melbourne today announced the receipt by the University of a research grant to further develop Pieris’ novel protein Anticalin®-brand therapeutic, PRS-060, in immunological diseases. The grant — which will support Pieris’ Australian subsidiary, Pieris Australia, and is disbursed by Australia’s peak medical research funding body, the National Health and Medical Research Council (NHMRC) — totals more than $AUS 500,000 and covers activities to advance PRS-060 for inhaled delivery to treat asthmatics.

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NDA For WuXi MedImmune’s Monoclonal Antibody Accepted For Review By CFDA

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WuXi PharmaTech (Cayman) Inc. (WX: Quote) announced that an Investigational New Drug or IND application for WuXi MedImmune’s novel anti-IL6 monoclonal antibody for rheumatoid arthritis has been accepted for review by the China Food and Drug Administration or CFDA.

In September 2012, MedImmune, the global biologics research and development arm of AstraZeneca, and WuXi AppTec formed the joint venture WuXi MedImmune Biopharmaceutical Co. Limited to develop and commercialize MEDI5117, a novel, investigational, long-acting monoclonal antibody for autoimmune and inflammatory diseases, the first such collaboration in China between a global company and a Chinese company to develop novel biologics.

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Maryland General Assembly Honors Chancellor Kirwan for 50 Years of Commitment to Higher Education in Maryland – USM

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The Maryland General Assembly recently honored University System of Maryland (USM) Chancellor William E. “Brit” Kirwan with a special tribute. In both chambers of the General Assembly, delegates and senators on March 20 recognized Chancellor Kirwan for his 50 years of service to Maryland higher education.

House Speaker Michael E. Busch and Senate President Thomas V. “Mike” Miller offered separate tributes to Kirwan, who has served as USM chancellor since 2002 and announced in May 2014 that he will step down from his leadership position. Kirwan will remain as chancellor through June 30, 2015. University of Massachusetts System President Robert L. Caret will succeed him.

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