News Archive

In an effort to tap patient communities for insights on drug development, AstraZeneca has inked a five-year deal with PatientsLikeMe, according to a company statement.

Ed Godber, executive vice president of Life Sciences Ventures at PatientsLikeMe, said unlike most of its pharma collaborations, which have been with U.S. affiliates of drug companies, “this one integrates us into the engine of R&D globally. AstraZeneca is putting the patient voice and PatientsLikeMe into the DNA of their innovation process.”

Lung disease lands thousands of patients in the hospital every year. And that’s where many of them stay, unable to breathe without a cumbersome respirator to help circulate air through their lungs.

Breethe Inc., a startup out of the University of Maryland, Baltimore, wants to change that experience. The company is developing a portable, artificial lung that will allow patients to continue treatment outside the hospital. Breethe on Monday announced it had finalized an agreement with UM Ventures, the university’s commercialization office, to license the technology behind its invention.

University of Maryland (UM) Ventures and Breethe, Inc. announced today that Breethe, an early-stage, Baltimore-based medical device company, has obtained exclusive rights to University of Maryland, Baltimore (UMB) intellectual property (IP) for the development of a wearable, portable blood pump oxygenator that will function as an artificial lung system for patients suffering from respiratory failure and cardiopulmonary collapse. Faculty at the University of Maryland School of Medicine (UM SOM) developed the core licensed technology, with Breethe also obtaining important supporting technology co-owned by UMB and University of Maryland, Baltimore County (UMBC) as part of the license agreement.  The Breethe team plans to leverage the technology to bring the first wearable ‘out-of-hospital’ artificial lung system to market. UMB has made a $100,000 investment in Breethe through UM Ventures.

All it takes is one hit. And Christy Wyskiel likes her chances.

Johns Hopkins University, where Wyskiel heads up technology commercialization, is among the institutions scrambling to transform more faculty research into startup companies, patents and licenses. Hopkins in 2014 reported $16.5 million in licensing revenue, but is still far behind universities that have been leaders in commercialization. Columbia University, for example, earned $150 million in licensing revenue last year.

AstraZeneca’s global biologics R&D arm MedImmune has received fast track designation from the US Food and Drug Administration (FDA) to develop MEDI8897, an investigational recombinant human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody (mAb).

This monoclonal antibody is being examined for the prevention of lower respiratory tract illness (LRTI) caused by respiratory syncytial virus (RSV) in infants and young children.

We’re back in Baltimore thanks to The University of Maryland’s Biotech Research and Education Program (BREP) who is sponsoring this BioBuzz networking event on April 9th at @HeavySeasAleHse.  Join us to share an evening with BREP and Baltimore’s growing Biotech community. Heavy Seas Alehouse is located in a very accessible part of the city and has plenty of free street parking and a garage directly across the street.

Another startup-focused program from TEDCO is on the way. The U.S. Economic Development Administration awarded the Maryland Technology Development Corporation (TEDCO) an innovation grant this week. TEDCO will use the $500,000 i6 Challenge award to launch a program for commercialization of medical devices. The program, called Maryland Structure Efficient Professional Product Development (mdSTEPP), is aiming to create 5-7 new medical device companies a year. It’s another example of the state working to turn the research that emerges from Maryland’s hospitals, labs and other centers into profitable businesses. The announcement also comes as University of Maryland officials are looking to expand the institution’s BioPark in Baltimore, and Johns Hopkins University is finally making the investment in commercialization that many have long wanted.

Foundation Medicine Inc. (NASDAQ:FMI) today announced the closing of its strategic transaction with Roche. This transaction included the purchase by Roche of approximately 15.6 million shares of common stock by means of a tender offer from Foundation Medicine stockholders at a price of $50 per share. Concurrently Roche also purchased an additional 5 million newly issued shares directly from the company at the same price per share for gross proceeds to Foundation Medicine of $250 million. As a result of these two related transactions Roche is a majority shareholder in Foundation Medicine. Foundation Medicine will maintain its operational independence with Roche having minority representation on Foundation Medicine’s Board of Directors.

When serial entrepreneurs Greg Cangialosi and Dave Troy launched the Baltimore Angels in 2009, the small group of investors heard pitches from hopeful entrepreneurs in a cramped Baltimore conference room, with maybe a pizza and bottle of water to share. Six years later, the Baltimore Angels are a crew of 40 investors, making deals upwards of $100,000. As Baltimore’s startup scene grows, Cangialosi is tightening the screws on the Baltimore Angels to attract new members, raise more money, ink more deals and be a driving force in the city’s entrepreneurship community.

STONY BROOK, N.Y., April 8, 2015 – The National Institutes of Health (NIH) has granted Stony Brook University’s Center for Biotechnology a three-year $3 million award through the SUNY Research Foundation to establish the Long Island Bioscience Hub (LIBH). The award is part of the NIH’s Research Evaluation and Commercialization Hub (REACH) program and one of only three granted nationwide. The LIBH will be a collaboration between Stony Brook University, Cold Spring Harbor Laboratory and Brookhaven National Laboratory, and is designed to help accelerate the translation of biomedical discoveries into new drugs, devices, and diagnostics to improve patient care and enhance health.