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New Enterprise Associates closes more than $3B in capital for new funds – Washington Business Journal

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New Enterprise Associates has closed more than $3.1 billion in new capital for its 15th fund and a joint “opportunity fund,” the Chevy Chase venture capital giant said Wednesday.

The raise marks the fourth consecutive $2.5 billion-plus fund and brings the total capital under the firm’s umbrella since its 1977 inception to nearly $17 billion.

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HHS announces $1 million in new grant programs to help improve sharing of health information

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National Coordinator for Health Information Technology Karen B. DeSalvo, M.D., M.P.H., M.Sc., announced today the availability of $1 million in grant funds to support community projects for the Community Interoperability Health Information Exchange (HIE) Program. The funding will help support and enable the flow of health information at the community level, leading to better care and better health.

The Community Interoperability and HIE program will provide funds to up to ten community organizations, state or local government agencies, or other community groups. The awards will help unlock health information and better integrate community resources advancing better care and healthier communities.

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NHLBI Funding & Research Opportunities and Announcements for April 14, 2015

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Funding and Research Opportunities

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:

Notices:

  • Notice of Potential Delays to NIH Issuing Awards in May 2015
  • Racial and Ethnic Categories and Definitions for NIH Diversity Programs and for Other Reporting Purposes
  • Reporting Publications in the Research Performance Progress Report (RPPR)

Program Announcements:

  • Administrative Supplements for Tobacco Regulatory Research on Tobacco Flavors and Flavorings (Admin Supp)
    • (PA-15-183)
    • National Institutes of Health, Food and Drug Administration, National Cancer Institute, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, National Institute of Dental and Craniofacial Research, National Institute of Environmental Health Sciences, Office of Disease Prevention
    • Application Receipt/Submission Date(s): Multiple dates, see announcement.

Please note that most links to RFAs, PAs, and Guide Notices will take you to the NIH Web site. RFPs will take you to FedBizOpps. Links to RFPs will not work past their proposal receipt date. Archived versions of RFPs posted on FedBizOpps can be found on the FedBizOpps site using the FedBizOpps search function. Under “Document to Search,” select Archived Documents.

National Institutes of Health
Food and Drug Administration
National Cancer Institute
National Heart, Lung, and Blood Institute
National Institute on Alcohol Abuse and Alcoholism
National Institute on Drug Abuse
National Institute of Dental and Craniofacial Research
National Institute of Environmental Health Sciences
Office of Disease Prevention
Application Receipt/Submission Date(s): Multiple dates, see announcement.

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PatientsLikeMe’s multiyear deal with AstraZeneca will impact global R&D

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In an effort to tap patient communities for insights on drug development, AstraZeneca has inked a five-year deal with PatientsLikeMe, according to a company statement.

Ed Godber, executive vice president of Life Sciences Ventures at PatientsLikeMe, said unlike most of its pharma collaborations, which have been with U.S. affiliates of drug companies, “this one integrates us into the engine of R&D globally. AstraZeneca is putting the patient voice and PatientsLikeMe into the DNA of their innovation process.”

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A UMB startup is developing a portable artificial lung – Baltimore Business Journal

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Lung disease lands thousands of patients in the hospital every year. And that’s where many of them stay, unable to breathe without a cumbersome respirator to help circulate air through their lungs.

Breethe Inc., a startup out of the University of Maryland, Baltimore, wants to change that experience. The company is developing a portable, artificial lung that will allow patients to continue treatment outside the hospital. Breethe on Monday announced it had finalized an agreement with UM Ventures, the university’s commercialization office, to license the technology behind its invention.

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Breethe Aims To Bring First Wearable ‘Out-Of-Hospital’ Artificial Lung System To Market – kcentv.com – KCEN HD – Waco, Temple, and Killeen

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University of Maryland (UM) Ventures and Breethe, Inc. announced today that Breethe, an early-stage, Baltimore-based medical device company, has obtained exclusive rights to University of Maryland, Baltimore (UMB) intellectual property (IP) for the development of a wearable, portable blood pump oxygenator that will function as an artificial lung system for patients suffering from respiratory failure and cardiopulmonary collapse. Faculty at the University of Maryland School of Medicine (UM SOM) developed the core licensed technology, with Breethe also obtaining important supporting technology co-owned by UMB and University of Maryland, Baltimore County (UMBC) as part of the license agreement.  The Breethe team plans to leverage the technology to bring the first wearable ‘out-of-hospital’ artificial lung system to market. UMB has made a $100,000 investment in Breethe through UM Ventures.

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How tech commercialization could pay off big for Johns Hopkins – Baltimore Business Journal

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All it takes is one hit. And Christy Wyskiel likes her chances.

Johns Hopkins University, where Wyskiel heads up technology commercialization, is among the institutions scrambling to transform more faculty research into startup companies, patents and licenses. Hopkins in 2014 reported $16.5 million in licensing revenue, but is still far behind universities that have been leaders in commercialization. Columbia University, for example, earned $150 million in licensing revenue last year.

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MedImmune gets FDA fast track status for MEDI8897 to prevent LRTI caused by RSV in infants – Pharmaceutical Business Review

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AstraZeneca’s global biologics R&D arm MedImmune has received fast track designation from the US Food and Drug Administration (FDA) to develop MEDI8897, an investigational recombinant human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody (mAb).

This monoclonal antibody is being examined for the prevention of lower respiratory tract illness (LRTI) caused by respiratory syncytial virus (RSV) in infants and young children.

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BREP Brings BioBuzz Back to Baltimore

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We’re back in Baltimore thanks to The University of Maryland’s Biotech Research and Education Program (BREP) who is sponsoring this BioBuzz networking event on April 9th at @HeavySeasAleHse.  Join us to share an evening with BREP and Baltimore’s growing Biotech community. Heavy Seas Alehouse is located in a very accessible part of the city and has plenty of free street parking and a garage directly across the street.

 

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Neuronascent Secures Financing for Development of Its Alzheimer’s Therapeutic – Market Wired

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CLARKSVILLE, MD–(Marketwired – Apr 6, 2015) – Neuronascent, a biopharmaceutical company developing non-invasive, neuron regenerative therapeutics aimed at reversing cognitive deficits in Alzheimer’s disease, today announced the closing of a round of financing for up to $1.2 million. Neuronascent’s human neuronal progenitor-based discovery platform identified a number of novel orally-available therapeutics that promote new neuron generation at the same time inhibiting loss of neurons. Proceeds from this first institutional investment will allow the development of Neuronascent’s lead Alzheimer’s candidate, NNI-362, to the point of first-in-human clinical testing. The Company expects to complete all IND-enabling studies in 2015, with the considerable support of the National Institute of Aging’s (NIA) Alzheimer’s Disease Translational Research Program.

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