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CEO’s Note: Dreaming It in Charm City — Sisu Global Health

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The field of blood study and blood-related product development is a small one, and the field of autotransfusion (blood recycling) is even smaller. It often seems like everyone knows everyone else. We’ve had a lot of great mentors in the blood space from afar, but it hasn’t been until we tapped into the inner workings of the Baltimore/DC area that we realized quite how small.

Just six weeks ago, we moved to the Charm City for the DreamIt Health Accelerator program from our medical device manufacturing home in Grand Rapids, Michigan. We were looking for other resources and mentors in both the blood transfusion and global health community to take our company to the next level, and we’ve found them.

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Immunocore and MedImmune Announce New Collaboration to Conduct Immuno-oncology Combination Trails in Melanoma

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AstraZeneca today announced that MedImmune, its global biologics research and development arm, has entered into a collaboration to conduct clinical trials in immuno-oncology with Immunocore Limited, a privately-held UK-based biotechnology company.

Under the terms of the agreement, Immunocore will conduct a Phase Ib/II clinical trial combining MedImmune’s investigational checkpoint inhibitors MEDI4736 (anti-PD-L1) and/or tremelimumab (anti-CTLA-4) with IMCgp100, Immunocore’s lead T-cell receptor-based investigational therapeutic, for the potential treatment of patients with metastatic melanoma.  MedImmune has an exclusive relationship with Immunocore for the development of IMCgp100 in combination with MEDI4736 and/or tremelimumab, and will have first right of negotiation for the future commercial development of these combinations for tumours expressing glycoprotein 100 (gp100), a tumour-associated antigen.

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Baltimore’s tech talent growth outpaces most other cities – Baltimore Business Journal

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Baltimore may not have the startup mecca reputation of Silicon Valley or Boston, but it is one of the fastest growing tech talent markets.

The city’s tech talent pool grew by 42 percent between 2010 and 2013, making Baltimore one of the fastest growing tech talent markets in the country, according to a new report by CBRE, a commercial real estate brokerage. Only San Francisco and the San Francisco Peninsula reported a faster growth rate than Baltimore. Tech talent grew 44 percent in those areas.

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How much of NEA’s new, $3.1 billion fund will finance healthcare companies? A third, perhaps.

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Venture firm New Enterprise Associates made some massive waves today on news that it’s closed its fifteenth – and largest – fund, which holds $3.1 billion. And a huge swath of that – 30 to 40 percent, according to Fierce – could likely be allocated to the healthcare space.

MedCity News reported initially on NEA’s plans to raise funds – it filed a document with the SEC in January indicating a $2.5 billion fundraise:

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Alexandria Real Estate Equities, Gaithersburg prepare to open wet lab incubator – Washington Business Journal

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Alexandria Real Estate Equities Inc. is opening a Gaithersburg wet lab space in a project that may help fill a gap left when Montgomery County’s biotech incubator shuttered last year.

Called Alexandria LaunchLabs, the new space will create five lab and office spaces to accelerate early-stage life science companies. Each will have about 1,200 square feet and have access to supporting infrastructure and amenities such as an on-site gym. BioHealth Innovation, a public-private partnership created in 2011 to foster health and life sciences commercialization in Maryland, will provide startup and entrepreneur-in-residence programs to guide the early-stage life science companies.

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Roche aims for 11 late-stage trials in cancer immunotherapy drug this year – Yahoo News

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Roche aims to have an immunotherapy cancer drug in 11 late-stage trials by the end of the year, the Swiss drugmaker’s head of medical affairs for oncology, Nico Andre, said at a conference on Monday.

The Basel-based company’s MPDL3280A, which is being tested in melanoma, as well as lung, bladder, kidney, bowel and blood cancers but has not yet been approved to treat any type of cancer, is the furthest developed of this class of drug. Some analysts have said such drugs could generate more than $30 billion in annual sales for the industry as a whole by 2025.

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A real estate empire grows in Kendall Square – Business – The Boston Globe

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Alexandria Real Estate Equities Inc. made its first modest investment in Kendall Square about 14 years ago, developing a blocky five-story building it named The Science Hotel.

The building, on Memorial Drive, was designed to be an incubator for biotechnology startups as the industry was just emerging in East Cambridge. In the following years, biotech grew explosively in the Kendall Square area, and Alexandria grew, too.

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New Enterprise Associates closes more than $3B in capital for new funds – Washington Business Journal

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New Enterprise Associates has closed more than $3.1 billion in new capital for its 15th fund and a joint “opportunity fund,” the Chevy Chase venture capital giant said Wednesday.

The raise marks the fourth consecutive $2.5 billion-plus fund and brings the total capital under the firm’s umbrella since its 1977 inception to nearly $17 billion.

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HHS announces $1 million in new grant programs to help improve sharing of health information

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National Coordinator for Health Information Technology Karen B. DeSalvo, M.D., M.P.H., M.Sc., announced today the availability of $1 million in grant funds to support community projects for the Community Interoperability Health Information Exchange (HIE) Program. The funding will help support and enable the flow of health information at the community level, leading to better care and better health.

The Community Interoperability and HIE program will provide funds to up to ten community organizations, state or local government agencies, or other community groups. The awards will help unlock health information and better integrate community resources advancing better care and healthier communities.

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NHLBI Funding & Research Opportunities and Announcements for April 14, 2015

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Funding and Research Opportunities

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:

Notices:

  • Notice of Potential Delays to NIH Issuing Awards in May 2015
  • Racial and Ethnic Categories and Definitions for NIH Diversity Programs and for Other Reporting Purposes
  • Reporting Publications in the Research Performance Progress Report (RPPR)

Program Announcements:

  • Administrative Supplements for Tobacco Regulatory Research on Tobacco Flavors and Flavorings (Admin Supp)
    • (PA-15-183)
    • National Institutes of Health, Food and Drug Administration, National Cancer Institute, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, National Institute of Dental and Craniofacial Research, National Institute of Environmental Health Sciences, Office of Disease Prevention
    • Application Receipt/Submission Date(s): Multiple dates, see announcement.

Please note that most links to RFAs, PAs, and Guide Notices will take you to the NIH Web site. RFPs will take you to FedBizOpps. Links to RFPs will not work past their proposal receipt date. Archived versions of RFPs posted on FedBizOpps can be found on the FedBizOpps site using the FedBizOpps search function. Under “Document to Search,” select Archived Documents.

National Institutes of Health
Food and Drug Administration
National Cancer Institute
National Heart, Lung, and Blood Institute
National Institute on Alcohol Abuse and Alcoholism
National Institute on Drug Abuse
National Institute of Dental and Craniofacial Research
National Institute of Environmental Health Sciences
Office of Disease Prevention
Application Receipt/Submission Date(s): Multiple dates, see announcement.

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