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Notes and Takeaways from JPM 2020

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The big deal about the just-completed J.P. Morgan (JPM) 38th Healthcare Conference had little to do with big M&A deals, because there weren’t any. This time last year, the $74-billion Bristol-Myers Squibb acquisition of Celgene was announced, as was Eli Lilly’s takeover of Loxo Oncology for $8 billion.

There were no such blockbusters this year, though there was an interesting potentially up-to-$2 billion-plus collaboration: MorphoSys outlicensed ex-U.S. commercialization rights to its anti-CD19 Fc-engineered antibody tafasitamab to Incyte, with the companies agreeing to co-commercialize the B cell malignancy candidate Stateside.

Image: A dearth of deals, Illumina’s double launches, and the usual crowds marked the 38th J.P. Morgan 38th Conference. – https://www.genengnews.com

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How Much Should I Pay The Directors On My Board In 2020?

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When was the last time you analyzed how much you should pay your board members? How do you know if you are paying too much or not enough? In this article we examine the results of our most recent research that highlights how much board members should receive in compensation.

Business size, industry, structure, complexity, the number of yearly meetings are just a number of variables you have to consider when setting your board remuneration programs. Private companies tend to struggle with board compensation because it is difficult to find accurate benchmarks for director pay.

 

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AMPEL BioSolutions Announces Gene-Based Lupus Diagnostic At Biotech Showcase In San Francisco

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SAN FRANCISCO, Jan. 17, 2020 /PRNewswire/ — AMPEL BioSolutions’ Co-Founder and COO/CSO Dr. Amrie Grammer today at the Biotech Showcase at JP Morgan Healthcare announces the kickoff of a Series A $12.5M raise to commercialize LuGENETM, a gene-based diagnostic.  AMPEL’s initial focus is Lupus, but the test can be used for many autoimmune or inflammatory diseases.  AMPEL’S goal is to have its test available for routine use by physicians within the next few years.

 

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The CEO Chronicles – Lessons Learned From A Serial CEO | LinkedIn

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Why me?

I have spent the last 20 years as a serial CEO of multiple healthcare startups, as well as spending the last 3 years as a corporate/strategic venture capitalist. I have made many mistakes and gotten lucky on more than a few occasions. What I hope to accomplish in this blog is simple: educate and, on a good day, entertain. There are many that are much, much more successful than me (nearly everyone in Silicon Valley!). There are some that are worse (also in Silicon Valley…e.g. Elizabeth Holmes re: Theranos). I am not from Silicon Valley. If you have questions, comments, or suggestions (future topics), please feel free to reach out to me.

Image: https://www.linkedin.com

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Seeking Partner to Help Save Womens’ Lives Through Easy-to-Use and Analyze Cervical Cancer Screening Test/MarkPap® System

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BioSciCon, Inc., a woman-owned small business based in Rockville, Maryland focused on providing a low-cost and accessible diagnostic system for the detection of cervical cancer announced today that it is seeking a partner to make its proprietary MarkPap® platform available to women in low- and middle-income countries.

According to BioSciCon Director and President of the Global Academy for Women’s Health Dr. Olivera Markovic, “In low- and middle-income countries (LMICs), thousands of women still are dying needlessly every year from cervical cancer due to the astonishingly low screening in LMICs for this highly preventable disease. Our kit and screening model, if applied as designed, could prevent the deaths of about 300,000 women annually, through improved and expanded screening and early detection of cervical cancer.”

The idea for BioSciCon was conceived by Drs. Olivera and Nenad Markovic upon discovery of a new bioactive protein residing only in specimens obtained from abnormal cervical tissues. Continued success of their team of scientists led to the development of a proprietary technology for visualization of this protein by simple laboratory pathology means known as the CAP-PAP Test. The MarkPap® System has been tested in more than 2000 women and proven to result in faster, less expensive and more accurate diagnosis of cervical cancer than the conventional Pap and liquid-based Pap test.  These improved outcomes have been documented in more than 60 publications in peer-reviewed  journals and in the reference guide “What Every Woman Should Know about Cervical Cancer”).  To further the company’s mission to save women’s lives through early intervention in LMICs, BioSciCon is seeking a partner to distribute MarkPap kits to underprivileged women in low resource settings.

Click here for more information.

 
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FARXIGA granted FDA Priority Review for patients with heart failure with reduced ejection fraction

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AstraZeneca today announced the US Food and Drug Administration (FDA) has accepted a supplemental New Drug Application (sNDA) and granted Priority Review for FARXIGA® (dapagliflozin) to reduce the risk of cardiovascular (CV) death or the worsening of heart failure (HF) in adults with heart failure with reduced ejection fraction (HFrEF) with and without type 2 diabetes (T2D).

The Prescription Drug User Fee Act date, the FDA action date for this supplemental application, is scheduled for the second quarter of 2020.

 

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Announcing IndoUSrare | LinkedIn

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Hi, I am Harsha Rajasimha, Founder and Chairman of IndoUSrare, an independent non-profit organization focused on helping patients with rare diseases of Indian origin in the USA, India and globally with a vision to build collaborative bridges between the east and the west to accelerate research and development of diagnostics and therapies through education, advocacy, research & grants.

 

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NCC PDI showcase event applications opens | Children’s National Hospital

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WASHINGTON – The National Capital Consortium for Pediatric Device Innovation (NCC-PDI), in collaboration with MedTech Innovator, is now accepting applications for its showcase pitch event on March 23, 2020, in College Park, Maryland. The competition is focused on pediatric devices in three areas of critical need: cardiovascular, orthopedic and spine, and neonatal intensive care unit (NICU).

Up to ten companies selected from this event will move on to the “Make Your Medical Device Pitch for Kids!” on Oct. 4, 2020 in Toronto, Canada, to compete for up to $250,000 in grant awards. These companies also receive a spot in the MedTech Innovator 2020 Accelerator – Pediatric Track, which provides a customized curriculum and in-depth mentorship.

 

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BioMarker Strategies Awarded Phase II National Cancer Institute Contract to Develop Novel Predictive Test for Response to Immunotherapies for Patients with Non-Small Cell Lung Cancer

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BioMarker Strategies, LLC, today announced that the National Cancer Institute (NCI) has awarded the Company a Phase II Small Business Innovation Research (SBIR) contract to continue development of its PathMAP® Immunotherapy test to predict clinical response to PD-1/PD-L1 targeted immune checkpoint inhibitors, both alone and in combination with chemotherapies, for individual patients with non-small cell lung cancer (NSCLC). The contract totals $1.5 million over two years.

Image: https://finance.yahoo.com

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