
Crab Trap Judges and Sponsors, Sally Allain, MSc., MBA Head, JLABS @ Washington, DC Johnson & Johnson Innovation – JLABS, Srujana Cherukuri, Ph.D., Chief Executive Officer, Noble Life Sciences, Inc. & Lora Green, Partner, Wilson Sonsini Goodrich & Rosati, join Rich Bendis on BioTalk to preview the event taking place live on September 21st, 2022 at USP in Rockville. For the first time in its history, this year’s Crab Trap winner will be eligible for a package of prizes worth more than $50,000.
Prizes for the qualifying Crab Trap winner include:
- A $10,000 cash prize from Wilson Sonsini
- A $5,000 cash from Montgomery County (for a firm headquartered in Montgomery County)
- A one-year residency at JLABS @ Washington, D.C.
- Preclinical CRO services from Noble Life Sciences.
Listen now via Apple https://apple.co/3Kr1FKU, Google https://bit.ly/3e46gGS, Spotify https://spoti.fi/3ctQ4Os, or Amazon Podcasts https://amzn.to/3qbvtSB
Pioneering life science projects focused on improving pediatric care will be on display at the Children’s National Research & Innovation Campus when the hospital hosts its 2022 Innovation Day on Friday, August 26. Hosted by Children’s National Innovation Ventures, the program’s goal is to showcase life sciences and healthcare projects that are mature enough to look for a co-developer, strategic partner, investor or licensing vehicle.
“For us, a successful Innovation Day means we are able to match these entrepreneurs with the strategic partner they need at this stage of their device development journey,” says Kolaleh Eskandanian, Ph.D., M.B.A., P.M.P., vice president and chief innovation officer at Children’s National Hospital and executive director of the Sheikh Zayed Institute for Pediatric Surgical Innovation.
ANNAPOLIS, MD—Governor Larry Hogan today announced Maryland programs funded by the State Small Business Credit Initiative (SSBCI) are open. Up to $198 million in federal small business relief is being administered by three state agencies: the Maryland Department of Housing and Community Development (DHCD), the Maryland Department of Commerce, and the Maryland Technology Development Corporation (TEDCO). These agencies will use funds to expand and enhance nine existing state business lending and investment programs.
Who doesn’t like a rooftop networking social? If you’re a fellow University of Virginia Darden School of Business alum and plan to attend our Alumni Weekend, join us on Saturday. See details, below.
AstraZeneca CEO Pascal Soriot raised questions Tuesday about the company’s future in vaccines while hinting at potential M&A activity on the near horizon.
In an interview with Reuters, Soriot discussed the company’s plans, which he said include building on its portfolio of antibody therapies. AstraZeneca is also considering bolt-on acquisitions in oncology and cardiovascular areas, Soriot said.
Getting out of the COVID-19 Vaccine Business?
Overall, in the COVID-19 space, the company has shifted its resources to antibody therapies.
Image: Pascal Claude Roland Soriot – 23 May 1959 (age 63) France – Wikipedia
Mon, Aug 22, 2022
HCV envelope-antibody interaction
The National Institute of Allergy and Infectious Disease (NIAID) awarded a $6.9 million grant to researchers at the Institute for Bioscience and Biotechnology Research (IBBR) to design a vaccine to combat the virus that causes Hepatitis C, an illness that affects an estimated 71 million people worldwide. Hepatitis C Virus (HCV) puts people at heightened risk for severe liver disease, including fibrosis, cirrhosis, and hepatocellular carcinoma (liver cancer). Although treatments are available, an HCV vaccine currently does not exist to help prevent infections and reduce the global burden of the disease.
The Johns Hopkins University Applied Physics Laboratory has been awarded a contract for research, development, test and evaluation of military-related technology that could be worth up to $10.6 billion, the Defense Department announced Monday.
The lab, based in Laurel, Maryland, was awarded a $4.4 billion cost-plus-fixed-fee, indefinite-delivery/indefinite-quantity contract for RDT&E programs throughout the DOD that fall “within its core competency areas including strategic systems test and evaluation; submarine security and survivability; space science and engineering; combat systems and guided missiles; air and missile defense and power projection; information technology, simulation, modeling, and operations analysis; and mission related research, development, test and evaluation,” according to the DOD contract award announcement.
Image: Photo of the Johns Hopkins University Applied Physics Lab’s Kossiakoff Center. (Photo courtesy of JHU-APL)
Novel Nanotechnology Supercharges Immune System Molecules to Fight Cancer
Researchers from Cytimmune Sciences presented new data at a cancer therapeutics conference in Boston, MA demonstrating the potential of their nanoparticle-based platform to supercharge synergistic immune system stimulators called cytokines.
SUMMARY OF DATA PRESENTED
- Data focused on industry leading, first-in-class, multi-cytokine immunotherapies
- CYT-IFNg-TNFa (A dual cytokine immunotherapy nanomedicine)
- 100x increase in direct cancer cell killing potency vs native cytokines
- 30x increase in cytokine accumulation in tumor tissue
- Induction of a cancer specific immune response after treatment
- Other novel cytokine-based immunotherapies
- Introduction of nanomedicines including combinations of IL-12, IL-2, IL-15 & IL-1b
- 175x increase in potency of IL-12 presented on nanoparticles vs. native IL-12
- CYT-6091 (high dose TNF alpha)
- Unpublished preclinical data showing CYT-6091 induces cytotoxic T-Cell tumor infiltration
- Phase 1 clinical safety data and preclinical mechanism of action data
Deloitte Consulting remained atop Modern Healthcare’s annual ranking of the largest healthcare management consulting firms based in the US.
Deloitte US’ sizable healthcare consulting practice realized $2.698 billion in revenue in 2021, with $962.8 million coming from healthcare providers.
Guidehouse jumped from third place 2020 to second place in 2021, achieving $970 million in healthcare consulting revenue, with approximately half from providers. The firm was boosted a significant industry acquisition in 2021, adding Dovel, an 1,800-person IT consultancy with a focus on health IT, life sciences, and public safety.
