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Ventana Medical Systems, Inc. and MedImmune collaborate to develop a custom PD-L1 Assay for immunotherapy clinical trials – MarketWatch

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Ventana Medical Systems, Inc. (Ventana), a member of the  Roche  Group and MedImmune, the global biologics research and development arm of AstraZeneca, today announced they are jointly developing a PD-L1 (SP263) immunohistochemistry assay to enroll patients in clinical trials for MedImmune’s MEDI4736 anti-PD-L1 therapy for non-small cell lung carcinoma. This includes the recently commenced MEDI4736 ATLANTIC trial that will enroll only patients who express PD-L1 as determined by the VENTANA assay.

MEDI4736 is an investigational, engineered, human monoclonal antibody directed against programmed cell death ligand 1 (PD-L1).   Signals from PD-L1 help tumors avoid detection by the immune system.   It is believed that by targeting PD-L1, MEDI4736 may block this ligand from sending out signals to T-cells to ‘ignore’ tumor cells, thereby countering cancer’s immune-evading tactics.  

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10 key takeaways from Health Datapalooza 2014

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Early June is Health Datapalooza time, and this year’s event was again a whirlwind of energy, insights, and over 2,000 very motivated and passionate health data enthusiasts (health datapaloozers doesn’t sound right). The hallway conversations provided tons of of pragmatic, productive and engaging conversations, inspired by keynotes and presentations from Todd Park, Bryan Sivak, Jeremy Hunt, Atul Gawande, Steve Case, Jerry Levin, Vinod Khosla, Kathleen Seblius, Dwayne Spradlin, Francis Collins, Fred Trotter, and many more (if you haven’t heard of some of them, look them up, it’s worth your time).  

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UEDA Awards of Excellence Nomination Deadline Extended to 6/10

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The University Economic Development Association (UEDA) is currently seeking nominations for its annual Awards of Excellence program, which recognizes cutting edge university-based economic development initiatives from across the country. The Awards of Excellence Program recognizes higher education institutions and their partners who are transforming their campuses into engines of economic prosperity through creative initiatives in five categories:

  1. Community Connected Campus: initiatives that promote the physical development of quality connected campuses and their surrounding communities;
  2. Research and Analysis:  initiatives that enhance the capacity of colleges and universities to provide new forms of research and tools for community, economic and workforce development practitioners;
  3. Leadership and Collaboration: initiatives that support the development of collaborative economic development strategies and the leaders required to implement them;
  4. Innovation and Entrepreneurship: initiatives designed to support startups, high-growth companies and clusters within a region; and
  5. Talent Development: initiatives that promote the development of 21st-century skills.
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He ditched med school for software that helps doctors

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ERIC KING, 30, of Northern Liberties, is founder and CEO of Grand Round Table, a startup on 3rd Street near Market that develops software to help doctors make complicated diagnoses. GRT, which launched in 2012, is getting the correct diagnoses about 70 percent of the time. The company, which was part of the first DreamIt Health accelerator in 2013, has three full-time employees and has raised $110,000 from the Wharton Venture Initiation Program and Ben Franklin Technology Partners.

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T2 Speakers Series – 6/11/14 “FastTrac TechVenture by Kauffman Foundation is now at Montgomery College!”

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Montgomery County ED

PRESENTER:

Karen Ambrose, Program Director, Business, Professional Licensure and Certification Programs
Montgomery College, Workforce Development and Continuing Education

ABSTRACT:

Montgomery College has joined with the world renowned Kauffman Foundation in support of current and future business owners before, during, and after the start-up process. Our plethora of courses is designed to meet the entrepreneurial needs of the aspiring business person and those who dream of business ownership.

Free monthly program offered through the Gateway to Innovation: Montgomery County Welcome Center for Federal and Academic Tech Transfer. For more information and additional calendar items, please visit TechTransferConnection.com. 

Engage with others in the tech transfer field by joining the Gateway to Innovation LinkedIn Group.

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‘Shocking’ garment designed by Johns Hopkins’ students could save lives | Hub

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Johns Hopkins biomedical engineering students have designed a lightweight, easy-to-conceal shirtlike garment to deliver lifesaving shocks to patients experiencing serious heart problems. The students say their design improves upon a wearable defibrillator system that is already in use and should help persuade patients at risk for sudden cardiac arrest to wear the system around the clock.

“In two studies, up to 20 percent of patients who received the defibrillator garment that’s already available did not keep it on all the time because of comfort and appearance issues, problems sleeping in it, and frequent ‘maintenance alarms,’ which occur when the device does not get a good signal from sensors on the patient’s skin,” says Sandya Subramanian, who led the undergraduate team that built the new prototype. “We set out to address these issues and design a device that heart patients would be more likely to wear for longer periods of time—because their lives may depend on it.”

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CytImmune raises $400K from Maryland, Montgomery County to advance nanomedicine trials – Washington Business Journal

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Rockville-based CytImmune Sciences Inc. has raised $400,000 from the Maryland Venture Fund, Montgomery County and an unnamed venture investor to push Aurimune — a drug that pairs a decades-old tumor-fighting agent with gold nanoparticles — into phase 2 trials.

The Maryland Venture Fund led the round with $200,000, with another $100,000 coming from the Montgomery County Department of Economic Development and the unidentified investor.

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GSK Wants To Give Away $5 Million To Non-Profits Working For A Healthier Philadelphia « CBS Philly

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GSK, formerly Glaxo SmithKline, and the Philadelphia Foundation have announced a $5 million grant package available to non-profits which will lead to healthier lives.

It’s called the GSK IMPACT Grant. IMPACT stands for Innovative, Measured, Partnered, Accountable, Community Centered and Transformative. Katie Loovis is GSK’s director of Community Relations.

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UMB creates position to encourage research, industry partnerships

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Simeon Taylor, MD, PhD, a seasoned pharmaceutical executive who has served in senior positions with Eli Lilly and Bristol-Meyers Squibb, has joined the University of Maryland, Baltimore (UMB) as industry liaison with its Center for Clinical Trials and Corporate Contracts (CCT).

In his new role for CCT, he will assist faculty in developing research strategies that will maximize corporate partnering and funding opportunities, and the possible creation of valuable intellectual property. CCT is part of the University’s Office of Research and Development, and the part-time consultancy is funded in keeping with the University’s 2011-2016 Strategic Plan

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