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Bert Vogelstein’s Liquid Biopsy Blood Test for DNA Could Stop Cancer – MIT Technology Review

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The answers Bert Vogelstein needed and feared were in the blood sample. 

Vogelstein is among the most highly cited scientists in the world. He was described, in the 1980s, as having broken into “the cockpit of cancer” after he and coworkers at Johns Hopkins University showed for the first time exactly how a series of DNA mutations, adding up silently over decades, turn cells cancerous. Damaged DNA, he helped prove, is the cause of cancer.

Now imagine you could see these mutations—see cancer itself—in a vial of blood. Nearly every type of cancer sheds DNA into the bloodstream, and Vogelstein’s laboratory at Johns ­Hopkins has developed a technique, called a “liquid biopsy,” that can find the telltale genetic material.

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Fall 2014 Regional Cohort Application – DC I-Corps

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DC I-Corps, a new, NSF-supported program designed to foster, grow and nurture an innovation ecosystem in the Mid-Atlantic Region, is now accepting applications for its fall cohort, beginning on October 9. Applications will be accepted on a rolling basis up until that date. Apply here.

Open to research teams and technology entrepreneurs from universities, federal laboratories, agencies and the general community, the free program guides researchers in exploring the commercial potential of their inventions.

Through DC I-Corps, you will:

  • Significantly improve your chances for SBIR and other grant funding, as well as early stage venture investment;
  • Work closely with six or more real-world advisors that have startup, venture capital, and technology commercialization experience over a six-week period; and
  • Come to a clear go or no-go decision regarding the commercial potential of your technology.

The program is geared towards innovations coming from engineering fields, medical/health/life sciences, and physical and computer sciences. DC I-Corps builds upon the successful National Science Foundation (NSF) I-Corps program.

The program is jointly offered by the University of Maryland, George Washington University, Virginia Tech, and Johns Hopkins University. For more information and to apply, technology researchers and entrepreneurs are encouraged to visit www.dcicorps.org.

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Contract Connections: Defense Labs Tech Transfer Tickets, Linthicum Heights – Eventbrite

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Are you a company in the fields of cloud computing, network security, interoperability, chemical and biological defense, infectious disease or vaccines?  Then you’ll want to attend the Maryland Department of Business and Economic Development’s Defense Labs Tech Transfer event which includes panel discussions and a tech transfer showcase.   Hear from Federal Labs including NSA, DISA, RDECOM, Edgewood Chemical Biological Center (ECBC), and USAMRIID, see demonstrations, speak with inventors, discuss available patents, licenses, collaborations and commercialization of new technologies to add to your portfolio.  

Featuring:    

Tech Transfer Showcase 9:00 a.m. –  4:00 p.m. – Visit the exhibit floor and see the latest technologies being developed by NSA, DISA, RDECOM, USAMRIID, and the Edgewood Chemical Biological Center. 

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Cerner/Siemens and the future of EHRs – Healthcare IT News

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As the dust settles from this past week’s mammoth $1.3 billion merger, Siemens Health Services CEO John Glaser tells Healthcare IT News what led up to the Cerner deal, how his experience as a health system CIO could help smooth integration challenges and what to expect – from the two companies and electronic health records in general – over the months and years to come.

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BioBuzz Montgomery County – August 27th

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Wrap up a great summer with one last BioBuzz networking event on August 27th from 5:00 – 7:30 p.m. at American Tap Room in Rockville, MD. This location is a short walk from the Metro located in the Rockville Town Center so there are no excuses not to come.

New this month, join us for Table Talks at BioBuzz.

For a new twist to the networking events, starting this month we will be hosting “Table Talks at BioBuzz”. We have enlisted industry experts on various topics who will be joining us to facilitate discussions around their industry related topics of choice. They will be strategically situated at a few tables at our venue so that you will be able to join which ever conversations interest you throughout the evening and participate in some stimulating discussions; while still enjoying the usual, casual atmosphere that BioBuzz offers each month.

This month’s Table Topics and discussion leaders will be announced later this week so keep an eye out.

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All eyes on Vermont as it blazes a single-payer trail

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Dr. Marvin Malek has been yearning and advocating for a publicly financed, single-payer health care system for at least two decades. Now, as Vermont stands on the threshold of being the first state to launch such a plan, he’s confessing to trepidation.

“I am pretty damn nervous,” he confided before bounding off for rounds at the Vermont Central Medical Center, still clutching the bicycle helmet he wore on his ride to work.

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Personalized Cancer Avatars Offer Clues to Treatment – MIT Technology Review

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At a laboratory in Baltimore, hairless mice kept in racks of plastic crates are labelled with yellow cards, each identifying a person fighting cancer. These mice are cancer “avatars”—the lumpy tumors visible under their skin come from actual patients.

The animals serve as personalized, living test tubes. Each mouse will eventually be treated with a different drug and its tumors measured. Results showing which medicine worked best will be sent back to a doctor trying to treat a difficult cancer case.

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Grand Challenges Canada Funds Seven New Global Health Innovations in ASEAN Countries

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Grand Challenges Canada, funded by the Government of Canada, has announced funding of seven projects implemented in ASEAN member countries. This funding, totalling $784,000, will support projects that combine scientific/technical, social and business innovation to solve pressing global health challenges. 

The funding was announced by Canadian Foreign Affairs Minister John Baird during a visit to Burma, where he is participating in the ASEAN-Canada Post Ministerial Conference. As one of ASEAN’s longest-standing dialogue partners, Canada has enjoyed positive and fruitful relations with the ASEAN region, cooperating on many issues, including regional integration, economic interests and innovation.

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Roche to buy disease research company

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The Swiss pharmaceutical giant Roche is set to pay $450 million for a Danish biotech company that develops drugs that silence microRNAs (something considered key to tackling certain diseases).

Roche is targeting the Danish biotech firm Santaris Pharma, according to The Wall Street Journal. Santaris Pharma A/S is a biopharmaceutical company founded in 2003 in Copenhagen. Santaris Pharma A/S has become a leading clinical-stage biopharmaceutical company that develops RNA-targeted medicines. Santaris works on developing drugs for a wide range of diseases using microRNA and mRNA. Their research focuses on infectious disease and metabolic disorders.

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Medtronic’s Attain Performa Quadripolar Lead and Viva Quad CRT-D Now FDA Approved

By News Archive

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The FDA has given Medtronic approval to introduce its Attain Performa Model 4298 quadripolar lead and the Viva Quad XT and Viva Quad S cardiac resynchronization therapy defibrillators (CRT-D) in the U.S.

Having four electrodes on a lead allows cardiologists to select from any one of 16 available pacing configurations. Additionally, the short distance between the inner two electrodes provides more ability to finely tune CRT-D therapy.

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