According to the latest research out of Johns Hopkins, a new blood test could predict a person’s risk for suicide through their DNA. The blood test would rely on genetics and offer many who are afflicted with mental illness and their doctors a new option in detecting suicidal behavior.

Johns Hopkins researchers Aleksander Popel and Jordan Green knew their research could serve a greater purpose outside their laboratory. But without any business experience, they knew they couldn’t do it alone.

With help from Hopkins’ tech transfer office and the Maryland Innovation Initiative, a state grant fund that invests in research projects with commercialization promise, the pair’s biomedical research is now a company — AsclepiX Therapeutics. The company is developing a better way to treat eye conditions caused by blood vessel abnormalities. Macular edema, which is common among people with diabetes and can lead to blindness, is an example.

Image: Jaclyn Borowski - At left, Niranjan Pandey, senior director of research and development, and Eric Bressler, research specialist, work in the lab at AsclepiX Therapeutics. 

Report: “Safe Science: Promoting a Culture of Safety in Academic Chemical Research”

Author: Committee on Establishing and Promoting a Culture of Safety in Academic Laboratory Research

Organization: National Research Council

Summary: The National Research Council formed a panel of university lab-safety experts after a series of campus accidents, including several deaths, emphasized that academic labs have a far worse safety record than their corporate counterparts do.

Regardless of your stance on Obamacare and Maryland’s Medicare waiver, you can’t ignore that health reform and technology are creating many opportunities for innovation. The BBJ is looking for those innovators. Please click below for contest information.

For years the standard operating procedure for the medical device world has been: Bring good tech to patients and be rewarded by the market. Healthcare reform and particularly the consolidation of doctor practices is making this model obsolete. Now the challenge is more along the lines of “Justify your existence.”

Device companies have to revamp the traditional business model to show how their products save money and help patients in the long term.

Image: http://medcitynews.com 

Genome scientist and entrepreneur J. Craig Venter is best known for being the first person to sequence his own genome, back in 2001.

This year, he started a new company, Human Longevity, which intends to sequence one million human genomes by 2020, and ultimately offer Web-based programs to help people store and understand their genetic data (see “Microbes and Metabolites Fuel an Ambitious Aging Project”).

Image: http://www.technologyreview.com - J. Craig Venter 

SBA Awards Montgomery County Chamber Community Foundation grant
to conduct veteran small business training course

ROCKVILLE, MD - The Montgomery County Chamber Community Foundation (MCCCF) is pleased to announce that the U.S. Small Business Administration (SBA) will support MCCCF in providing technical training to veteran-owned businesses seeking federal procurement opportunities. Through a Cooperative Agreement with SBA, the Foundation's National Center for Veteran Institute for Procurement (VIP) will expand and host three training sessions a year (over a twelve month period) to support up to 150 service-disabled veteran-owned small business (SDVOSB) and veteran-owned small businesses (VOSB) to attend the program.

Education technology, or ed-tech, is getting big in Baltimore and local experts think Maryland has a shot at being a leader in this technology niche.

But it won’t happen overnight.

“I think we have a unique opportunity to build an ecosystem,” said Frank Bonsal III, an ed-tech venture capitalist who leads Towson University’s business incubator. “An ecosystem takes 20 years to build. We’re on year three.”

Image: Jaclyn Borowski - Andrew Coy, executive director of the Digital Harbor Foundation, says students should play a bigger role in growing ed-tech. 

When it comes to raising capital for a tech startup, savvy entrepreneurs know how important it is to hustle. From trying to attract the attention of VCs to appearing on television shows like ABC’s Shark Tank, these days when it comes to raising cash, everyone is out to get their share.

However, you may be surprised to learn that in this high-tech world, one very traditional institution is looking for smart entrepreneurs to give money to. Aspiring entrepreneur, meet the Small Business Administration (SBA).

With plans to couple Johns Hopkins Medicine’s research cachet and Kaiser Permanente’s population health prowess, the two health giants announced a new “strategic collaboration” on Tuesday.

Kaiser Permanente of the Mid-Atlantic States and Hopkins officials say they will collaborate on patient care by sharing data from electronic medical records and developing better health care models based on evidence of what's worked best. Kaiser will work closely with Suburban Hospital in Bethesda, which is part of the Johns Hopkins network.

Image: http://m.bizjournals.com 

A $10.7 million grant to the University of Maryland School of Dentistry and the University of Maryland School of Medicine will fund the collaborative study of biomarkers associated with sexually transmitted diseases such as chlamydia, in hopes of finding new ways to predict the infection and developing new vaccines or treatments. The five-year grant from the National Institute of Allergy and Infectious Diseases is the renewal of a previous $12 million, five-year grant awarded in 2009, bringing the project's total to $22.7 million.

Image: http://www.oea.umaryland.edu 

What do you need to turn a brilliant idea into a business? “A good morale boost,” says Abhishek Motayed, Founder and President of N5 Sensors, Inc. of Rockville. Motayed had that boost this month when N5 Sensors received two Small Business Innovation Research (SBIR) awards totaling $250,000. The grants came from the Environmental Protection Agency (EPA) and the National Science Foundation (NSF) towards N5 Sensors work developing low-power, computer chip-size benzene, carbon monoxide, and ammonia sensors.

Image: http://umdtechtransfer.wordpress.com - Pasquale Ferrari, Ratan Debnath, Abhishek Motayed 

Maryland Health Secretary Dr. Joshua Sharfstein will step down in January to join Johns Hopkins University.

Sharfstein's move comes as Maryland is trying to revamp its failed health exchange in time for November open enrollment and as Gov. Martin O'Malley's administration winds down.

Image: Nicholas Griner Maryland Health Secretary Dr. Joshua Sharfstein is stepping down in January and will join Johns Hopkins University. 

The Montgomery County Council gave final approval Tuesday to an ambitious land-use plan designed to spur creation of a new science-focused town center in the county’s long-neglected eastern sector.

The White Oak Science Gateway Master Plan envisions housing, retail and a hub for medical and life-sciences research adjacent to the Food and Drug Administration headquarters at Route 29 and Industrial Parkway. The plan also adjusts zoning and land-use regulations with the goal of energizing new residential construction and commercial renewal in the White Oak and Hillandale communities.

The FLC planner visually communicates the outstanding research and development efforts of the federal laboratory system. Images and captions tell the story of the technology's scientific relevance and potential impact.

Printed annually, the planner is distributed to over 10,000 recipients, including members of Congress, scientists, researchers, agency representatives, laboratory directors, technology transfer professionals, students, academia, and members of industry.

Image: http://www.federallabs.org 

QIAGEN (NASDAQ: QGEN; Frankfurt, Prime Standard: QIA) today announced a collaboration agreement with AstraZeneca PLC (LSE, NYSE and OMX: AZN) for the co-development and commercialization of a liquid biopsy-based companion diagnostic to be paired with IRESSA, AstraZeneca's targeted therapy for non-small cell lung cancer (NSCLC). The project builds on a master framework agreement signed by both companies in 2013 and aims to develop and market a novel QIAGEN companion diagnostic that analyzes plasma samples to assess EGFR mutation status in NSCLC patients. The assay will be designed to guide the treatment of NSCLC patients with Astra Zeneca's oral monotherapy anti-cancer treatment when tumour tissue is not available. QIAGEN already offers the therascreen EGFR RGQ PCR Kit (therascreen EGFR test) as a tissue-based companion diagnostic for lung cancer patients, which was approved in the U.S. by the FDA in July 2013 and in China in May 2014.

Baltimore startup Quantified Care thinks it's possible for doctors to do an entire check-up with a smartphone and a bag of gadgets. It wants to sell you all of it — including the bag. Quantified Care is making a business of finding the most useful smartphone apps and devices for doctors and is developing software to help docs analyze data across devices. The company also runs an e-commerce website at which doctors can buy the devices it backs.

Image Courtesy of phanlop88 / FreeDigitalPhotos.net

NEW YORK (Reuters) - Ditching handshakes in favor of more informal fist bumps could help cut down on the spread of bacteria and illnesses, according to a study released on Monday.

The study in the American Journal of Infection Control found that fist bumps, where two people briefly press the top of their closed fists together, transferred about 90 percent less bacteria than handshakes.

Image: By The U.S. Army (Fist bump) [CC-BY-2.0 (http://creativecommons.org/licenses/by/2.0)], via Wikimedia Commons 

In these times of tight budgets and rapidly evolving science, we must consider new ways to invest biomedical research dollars to achieve maximum impact—to turn scientific discoveries into better health as swiftly as possible. We do this by thinking strategically about the areas of research that we support, as well as the process by which we fund that research.

Millions of people make a living without ever setting foot in an office. Particularly in technology, companies are moving away from just outsourcing rote tasks to remote workers and toward building entirely distributed teams. One leader is Elance-oDesk, the largest online marketplace for freelance talent. In addition to providing a platform for distributed and part-time work, the company practices what it preaches. Telecommuting in the United States increased by as much as 79% (paywall) between 2005 and 2012.

We all struggle for a moment of insight. Whether you’ve been banging your head against the wall for days or just woke up to a problem this morning, the desire for a creative boost is a powerful one. It’s the same feeling that plagues writers facing a blank page or advertisers developing a brand’s next campaign—and learning how to achieve it can have a profound impact. Here are some tips to avoid your next headache or create something the world has never seen before:

The Global Innovation Index (GII) report, jointly produced by Cornell University, Insead and Wipo every year, has become a leading source of reference on innovation.

The theme of GII 2014, released on the 18th of July, is ‘Human factor in innovation’. The report covers 143 economies around the world and ranks them on a score of 0-100, using 81 different indicators to gauge innovation capabilities and results. Consistent with the rankings of the past GII reports, the top ten economies in the global innovation index 2014 are Switzerland, UK, Sweden, Finland, Netherland, USA, Singapore, Denmark, Luxemburg and Hong Kong (China), all high income countries, hence pointing towards a clear income-innovation link.

In 1957, eight entrepreneurs decided to do something that seemed crazy. They launched a new tech company called Fairchild Semiconductor in a small town south of San Francisco. The entrepreneurs had a difficult start, but Fairchild eventually became the first major computer chip company in the region.

Montgomery County plans to launch a major technology initiative in its public schools in August, providing 40,000 laptops and tablets to students as part of a project that will expand quickly in coming years, officials said Thursday.

It helps to have a friend. And for several pharma giants scrambling to cut R&D costs, those friends are venture capital firms that co-invest in startups whose new drugs and platform technologies appear attractive. In some cases, these pharma-venture “alliances” launch the startups, using the expertise of VC firm partners and company executives.

Infectious diseases, pathogens and bioterrorism agents are all inside a new building downtown. Jessica Kartalija explains it’s great news for researchers at Johns Hopkins. It’s the newest addition to the Baltimore Science and Technology Park at Johns Hopkins. Inside, it’s a state-of-the-art lab that will keep Maryland on the cutting edge of public health and technology.

Founders Fund already stands out for backing startups with radical ideas, including Counsyl, Hampton Creek, Planet Labs, and SpaceX. Now the venture firm is making a formal commitment to funding startups in aeronautics, life sciences, nanotechnology, and other geeky realms. Founders Fund has dedicated a small percentage of its new $1 billion fund to a new initiative called FF Science, through which the firm will make seed-stage deals.

Kaiser is well known healthcare delivery model and outcomes, but, it turns out, it’s also among the best at engaging members via the web and mobile apps. The organization says in its 2013 annual report (just released) that about 4.4 million of its 9.1 million members use its online health management platform My Health Manager.

While considerable attention has been heaped on the public health insurance exchanges over the year, private health insurance exchanges “are experiencing hyper-growth” and enrollment could exceed that of public exchanges by 2017, “if not sooner,” according to Accenture.

Qiagen has acquired an exclusive global license from the University of Tokyo for the biomarker SF3B1. The company said it sees potential for developing companion diagnostics to guide myelodysplastic syndromes (MDS) treatment with new anticancer compounds under development that target the SF3B1 gene.

The Intellectual Property Owners (IPO) recently published a list of the top 100 universities worldwide granted U.S. patents in 2013, and among them were three local schools: Johns Hopkins University, the University of Maryland and the University of Virginia.

Inside sources reveal that Indian pharmaceutical generics firm Lupin, along with other U.S. pharma firms, is considering bidding for GlaxoSmithKline’s auctioned mature and generic drugs.

GSK seeks to divest its lineup of mature drugs in an effort to improve its growth profile by getting rid of its off-patent drugs in North America and Western Europe. The drugs are estimated to bring in annual sales of 1 billion pounds and are expected to fetch two to three times the price on the auction block.

The startup world will perk up to hear that RockthePost and CoFoundersLab recently merged to form Onevest. Together the two companies will provide a single source for startup founders to not only find investors but also find the right co-founders all online.

Jennifer Hammaker has watched biotech company respEQ Inc. grow from an experiment in a Johns Hopkins lab to a fledgling startup now looking for investors.

RespEQ is a prime example of what Hammaker, who leads the Maryland Innovation Initiative, hopes the state's research commercialization program will produce more of in the future.

Apollo Hospitals today announced a partnership with Strand Life Sciences to launch the latter’s genomic tests across its hospitals.

The partnership in gene-based diagnostics with the Bangalore-based healthcare research company will help doctors at Apollo to develop personalised medicine for targeted treatments and better patient outcomes.