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A quick note: Nature announced yesterday that it will make all of its articles free to view, read, and annotate online. That applies to the historic science journal (launched in 1869) and to 48 other scientific journals in Macmillan’s Nature Publishing Group (NPG). Other titles include Nature Genetics, Nature Medicine and Nature Physics.

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"Today, on this stage in the auditorium of Richard Montgomery High School - a magnet school that symbolizes the quality education that is Montgomery County - I stand before you with great humility and excitement about the future as I begin my third term as your County Executive."

"I have learned throughout my life that families are our “links” to our past, our anchors in the present, and bridges to our future. So, to my family, your love, support and patience have kept me grounded."

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The Washington Business Journal interviewed Leslie Ford Weber, JHU's director of the Montgomery County Campus and of government and community affairs for Montgomery County. The feature ran as an Executive Profile on Nov. 14, 2014. It was written by Vandana Sinha, an assistant managing editor at the Washington Business Journal. The photo was taken by Joanne S. Lawton.

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That next blockbuster drug? It all begins with a hypothesis: GlaxoSmithKline just announced the winners of its second Discovery Fast Track Challenge – a competition that teams up American and European academia with GSK researchers to speed up their search for new therapeutics.

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David Chalker, 50, has excruciating pain in his hip. He’s an Army veteran and because of the pain, he had to leave his job as a machinist, which left him in a great deal of debt and unable to pay for health insurance. He, his wife, and his three daughters needed to move in with his in-laws as a result.

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Small businesses are a major driver of high-technology innovation and economic growth in the United States, generating significant employment, new markets, and high-growth industries.1 In this era of globalization, optimizing the ability of small businesses to develop and commercialize new products is essential for U.S. competitiveness and national security. Developing better incentives to spur innovative ideas, technologies, and products—and ultimately to bring them to market—is thus a central policy challenge.

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An experimental vaccine to prevent Ebola virus disease was well-tolerated and produced immune system responses in all 20 healthy adults who received it in a Phase 1 clinical trial conducted by researchers from the National Institutes of Health. The candidate vaccine, which was co-developed by the NIH's National Institute of Allergy and Infectious Diseases (NIAID) and GlaxoSmithKline (GSK), was tested at the NIH Clinical Center in Bethesda, Maryland. The interim results are reported online in advance of print in the New England Journal of Medicine.

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Funding and Research Opportunities

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:
Notices:

  • NIH Implementation of the US Government Policy on Institutional Oversight of Life Sciences Dual Use Research of Concern
  • Publication of Notice of Proposed Rulemaking for Clinical Trials Registration and Results Submission under FDAAA
  • NIH Request for Public Comments on the Draft NIH Policy on Dissemination of NIH-Funded Clinical Trial Information
  • Request for Information (RFI): Inviting Comments and Suggestions on the Reagent-Related Barriers to Reproducible Research
  • Reminder: Annual Reports to the Office of Laboratory Animal Welfare due January 31, 2015
  • Notice of Intent to Publish a Funding Opportunity Announcement for Sudden Death in the Young: Population-Based Studies (U01)

Program Announcements

  • Systems Science and Health in the Behavioral and Social Sciences (R21)
    • (PAR-15-047
    • Office of Behavioral and Social Science Research
    • National Cancer Institute
    • National Institute on Aging
    • National Institute on Alcohol Abuse and Alcoholism
    • National Institute of Biomedical Imaging and Bioengineering
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development 
    • National Institute of Dental and Craniofacial Research
    • National Institute of Environmental Health Sciences
    • National Institute of Mental Health
    • National Institute of Nursing Research
    • Office of Disease Prevention
    • Application Receipt/Submission Date(s): Multiple dates, see announcement.
  • Systems Science and Health in the Behavioral and Social Sciences (R01)
    • (PAR-15-048
    • Office of Behavioral and Social Science Research
    • National Cancer Institute
    • National Institute on Aging
    • National Institute on Alcohol Abuse and Alcoholism
    • National Institute of Biomedical Imaging and Bioengineering
    • Eunice Kennedy Shriver National Institute of Child Health and Human Development 
    • National Institute of Dental and Craniofacial Research
    • National Institute of Environmental Health Sciences
    • National Institute of Mental Health
    • National Institute of Nursing Research
    • Office of Disease Prevention
    • Application Receipt/Submission Date(s): Multiple dates, see announcement.
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In 2015, hospitals will – and should – make more advanced use of "third platform" technologies based on mobile tools, social channels, data analytics and the cloud, according to a recent report from IDC Health Insights.

With healthcare costs unsustainable, but these new technologies now ubiquitous, IDC officials say hospital CIOs will increasingly be turning to new tools – especially as consumers expect healthcare to be as responsive to their wants and needs as other industries.

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Any small business or venture capital company interested in Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) funding opportunities should pay close attention to the Small Business Administration's (SBA) recent request for public comments, by January 6, 2015, on data rights and Phase III funding, and a recent Government Accountability Office (GAO) report identifying the National Institutes of Health (NIH) and Department of Energy's Advanced Research Projects Agency-Energy (ARPA-E) as the two agencies presently accepting applications from majority-owned portfolio companies.

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Lacrosse sticks, construction models and surgical tools — these are all things Baltimore companies are making with the help of 3-D printing.

Three-dimensional printing was invented decades ago but has really taken off in the last few years. Printers are more affordable (you can get one for your desktop for the price of a MacBook Pro). And printing material has advanced significantly, to include more durable plastics, metal and more.

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British drugmaker AstraZeneca plans to spend $200 million over the next three years, expanding its manufacturing facility in Frederick, Md., and hiring an additional 300 workers at the site, executives said.

The decision further cements Gaithersburg-based MedImmune, an AstraZeneca company, as the crown jewel of Maryland’s life sciences industry.

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Nestled in a quiet industrial park in Redmond, Washington, not too far from the Microsoft headquarters, is a small biotech start-up with both an interesting technology they are bringing to market, as well as a capital partner that suggests some ways in which global biotech research, venture capital and commercialization are going to change.

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Digital technologies such as electronic medical records, mobile devices, and analytics offer the potential to transform health care. Whether it’s a patient using her smartphone to better manage her diabetes, a provider monitoring a patient for arrhythmia remotely, or an electronic health-record system alerting a clinician of a potential drug allergy, digital technologies can create meaningful value for patients and practitioners alike. Yet there are significant barriers to the development and adoption of such technologies that academic medical centers are uniquely positioned to overcome.

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Myron M. Levine, MD, DTPH, director of the University of Maryland School of Medicine Center for Vaccine Development (CVD), and Dean E. Albert Reece, MD, PhD, MBA, announced today the start of a clinical trial in Baltimore to evaluate different dosage levels of a promising experimental Ebola vaccine developed by the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and GlaxoSmithKline (GSK

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There are presently massive shifts occurring in the competitive global landscape of health, and particularly in the life sciences. As we approach 2015, it is imperative that leaders in the health space understand the trends and shifts happening around them, not only in the US, but also in international markets, cities and service lines.

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Drug giant AstraZeneca will expand its biologics manufacturing center in Frederick and add hundreds of jobs to its operations there.

The drug giant will spend more than $200 million to increase production capacity. MedImmune, AstraZeneca's biologics research and development arm, has more than 120 drugs in its research pipeline, including more than 30 in clinical development. AstraZeneca says the expansion will support its research.

SBIR STTR

Few businesses owned by venture capital firms have been awarded Small Business Innovation Research awards since this program was opened to them two years ago.

Through the SBIR program, 11 federal agencies spend at least 2.8 percent of their outside research budgets with small businesses. Only two of these agencies — the National Institutes of Health and the Advanced Research Projects Agency-Energy — have allowed VC-owned businesses to compete for SBIR awards, according to a new Government Accountability Office study.

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The Tech Council of Maryland (TCM), Maryland’s largest technology trade association for life science and technology, today announced that it will honor former Lockheed Martin Corporation Chairman and CEO Norman Augustine, MedImmune, Inc. Founder Dr. Wayne Hockmeyer and University System of Maryland Chancellor William Kirwan with its 2015 Lifetime Achievement Awards. The awards will be presented during TCM’s Lifetime Achievement Gala, February 19, 2015.

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Health tech incubator MATTER has secured $4.4 million to build the next generation of health IT, medical device, diagnostics and biopharma companies in Chicago. The funding was led by twenty two local companies mostly focused in the tech and healthcare sectors complementing the initial $2.5M grant and $1.5M loan provided by the State of Illinois. This brings MATTER’s total funding to more than $8M to build a viable health tech hub in Chicago. 

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Surgery is an art form for Johns Hopkins surgeon Dr. Amir Dorafshar, who on a November morning spent four hours smoothing the point out of a child's skull.

The procedure, needed to allow the 18-month old's brain to grow properly and avoid developmental disorders, requires taking apart the skull in pieces, then putting it back together.

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Unlock your molecule’s potential with the help of EMD Millipore’s Emerging Biotech Grant Program

At EMD Millipore, it’s our goal to help advance lifesaving drugs to market. We understand the challenges that emerging biotech companies face in their quest to quickly push the next generation of drugs to market. We want to help you succeed.