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Moving to advance its leadership in developing vaccines for important public health and biodefense needs, Vaxin Inc. today announced that it has entered into a definitive agreement to acquire Immune Targeting Systems (ITS) Ltd. Vaxin is a clinical stage vaccine development company headquartered in Gaithersburg, Maryland. ITS develops novel T-cell vaccines at its operations in the United Kingdom and France. The deal is an all-stock transaction and is subject to customary closing conditions. The combined company will be known as Vaxin Inc.

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Crystal City-based Disruption Corp. is partnering with Maryland-based Greenspring Associates, a $3 billion fund of funds that backs some venture capital firms that actively invest in the region, including New Enterprise Associates, Revolution Growth and True Ventures.

Ashton Newhall, co-founder of Greenspring Associates, told me he believes Disruption and Greenspring are "philosophically aligned" on the possibilities of using data analytics to make sounder investments in startups and the private market broadly.

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At The MidAmerica Healthcare Venture Forum hosted at Chicago’s Fairmont Hotel on March 10 and 11, Healthbox’s Maria Siambekos will host a session about the growing role of healthcare accelerators. Do investors invest in them?

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Enterprise Therapeutics Ltd, a drug discovery company focused on new therapeutics for respiratory diseases, today announced that it has secured £1.6m ($2.4m) in initial Series-A financing from Epidarex Capital. The proceeds will fund, in parallel, low molecular weight drug discovery and new target identification programs. The company will be based at the University of Sussex.

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This is a Request for Proposal to lease the Good Manufacturing Practices (GMP) facility located at the Institute for Bioscience and Biotechnology Research (IBBR), on the University System of Maryland's Shady Grove campus at 9600 Gudelsky Drive, Rockville, MD 20850.

IBBR is a University System of Maryland joint research enterprise between the University of Maryland College Park, The University of Maryland Baltimore and the National Institute of Standards and Technology. IBBR's Vision and Mission are as follows:

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Johns Hopkins University President Ronald Daniels has seen plenty of innovation at the world-renowned research institution he leads. In opening a second incubator in East Baltimore, university officials believe they can get another benefit from the innovation.

“It’s happened before at Hopkins and it’ll happen again,” Daniels said of inventions that come out of the university. “But this time, we’re going to make some money on it.”

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Sucampo Pharmaceuticals, a global biopharmaceutical company, announced that Sucampo and R-Tech Ueno, Ltd. (RTU), have entered into a stipulation and licence agreement with Par Pharmaceutical, Inc. (Par). The agreement states that in limited circumstances, Sucampo or RTU would grant Par a licence for a generic version of the RESCULA (unoprostone isopropyl ophthalmic solution) 0.15 per cent product approved for the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension prior to the latest expiration date of the patents, which is July 2021. Par had previously submitted an Abbreviated New Drug Application to the US Food and Drug Administration requesting approval to market, sell, and use a generic version of RESCULA.

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Maryland could establish a $5 million fund to put toward tax credits for individuals and firms who invest in startup companies.

Startup and investor advocates, including the Greater Baltimore Committee, have said they will push for the state to create a new tax credit specifically for angel investors who give money to companies at their earliest stages, when they often struggle to bring in needed cash. A bill introduced by Baltimore City Democrat Sen. Catherine Pugh earlier this month details how the tax credit would work and who could qualify as an investor and startup recipient.

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Four University System of Maryland schools rank among the top 100 public universities in the country, according to a new statistical analysis by The Business Journals.

University of Maryland, College Park, scored highest among Maryland's public universities, coming in at No. 8 out of 484 schools nationwide. St. Mary's College of Maryland; University of Maryland, Baltimore County; and Towson University also ranked in the top 100. Salisbury University ranked 107th.

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April 27-29, 2015 - Boston, MA

Partners HealthCare is proud to announce the 2015 World Medical Innovation Forum, an annual gathering in Boston of more than 1,000 top innovation decision makers. The inaugural event will focus on neurosciences and be held on April 27-29, 2015. The goals of this three-day event are to identify today’s leading neuroscience innovations, address unmet needs, and discuss the critical issues affecting technology development and implementation in this new, evolving era of value-based care.

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National Institutes of Health director Francis Collins kicked off a two-day meeting in Bethesda, MD, this morning to discuss how to turn President Obama’s call for a national health research database into reality. The database, which NIH officials are calling the National Research Cohort, is one of two main thrusts of the administration’s precision medicine initiative.

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Fourteen years ago, during the darkest moments of the “stem-cell wars” pitting American scientists against the White House of George W. Bush, one group of advocates could be counted on to urge research using cells from human embryos: parents of children with type 1 diabetes. Motivated by scientists who told them these cells would lead to amazing cures, they spent millions on TV ads, lobbying, and countless phone calls to Congress.

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GlaxoSmithKline (GSK) has taken control of Swiss company GlycoVaxyn in a $190m deal that bolsters its early vaccines pipeline.

GSK already owned a stake in GlycoVaxyn and had been working with the company since 2012 on the development of conjugate vaccines for bacterial infections. 

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District regulators approved the city’s first equity crowdfunding campaign last week. It was also the only application they’ve received to date.

The Department of Insurance, Securities and Banking approved equity crowdfunding rules last October as a way for the city’s entrepreneurs to raise small sums of money from city residents in exchange for a piece of their business.

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Swiss cancer drugs giant Roche (ROG: SIX) has acquired Signature Diagnostics, a privately-held company based in Potsdam, Germany. Financial terms of the transaction, which is the fifth deal in the past year aimed at building Roche’s molecular diagnostics business, were not disclosed.

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Google is altering the way it displays search results. Over the next few days, Google Search will begin to dish out health bits of facts with search news. This is Google’s new attempt at health news, in fact, this could be a way to reimagine the now defunct Google Health.

This is not a first for Google. Its feet are firmly planted in the health space, having previously launched feature where people can connect to a doctor via video and its .

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It takes just one idea to change the world

The EY Entrepreneur Of The Year™ Award has become the mark of world-class individuals leading world-class companies. We invite you to be part of this exciting program.

About the Entrepreneur Of The Year Program

EY Entrepreneur Of The Year honors entrepreneurs whose ingenuity, hard work and perseverance have created and sustained successful, growing business ventures. The program is celebrating its 29th year and has expanded to more than 140 cities and 50 countries around the world. EY forms a group of individuals from the business community to participate as the independent panel of judges for the program. This panel is made up of past award winners and C-suite leadership of high-growth entrepreneurial organizations. It also includes influential business leaders from the venture capital and private equity communities.

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The recent February issue of Health Affairs, which features a series of articles on innovation, provides us with an opportunity to examine the state of America’s innovation ecosystem for medical technology. This ecosystem has produced a myriad of medical advances, ranging from advanced imaging to molecular diagnostics, minimally invasive surgical tools, and incredibly sophisticated implants. These technologies have shortened hospital stays, reduced the economic burden of disease, and saved and improved millions of lives.

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Funding and Research Opportunities

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:
Notices:

  • Registration Open for the 2015 NIH Regional Seminar on Program Funding and Grants Administration Baltimore, MD
  • Request for Information: Sustaining the Biomedical Workforce and a Potential Emeritus Award for Senior Researchers
  • NIH Interim General Grant Conditions Implementing New HHS Grants Regulations (Uniform Guidance)
  • Notice of Pre-Application Webinar for PA-14-015 Ruth L. Kirschstein National Research Service Award (NRSA) (Parent T32) Related to the Creation of New NHGRI Postdoctoral Training Programs in Genomic Medicine Res


Please note that most links to RFAs, PAs, and Guide Notices will take you to the NIH Web site. RFPs will take you to FedBizOpps. Links to RFPs will not work past their proposal receipt date. Archived versions of RFPs posted on FedBizOpps can be found on the FedBizOpps site using the FedBizOpps search function. Under “Document to Search,” select Archived Documents.

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Crowdfunding is a hot idea in small biopharma, but a lot of people don't quite know what to make of it. I've written about some academic examples of it, and I think that's a good use of the idea. People can donate in the expectation that they're helping along a research project, not because they're looking for a big return on their money.

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The NFL, GE, and Under Armour officials announced that they have joined with the U.S. Department of Commerce's National Institute of Standards and Technology (NIST) to launch Head Health Challenge III, an open innovation competition to advance materials that better absorb or dissipate energy. These new materials could improve the performance of protective equipment for athletes, military personnel and those in dangerous occupations.

BioHealth Innovation, Inc. (BHI), a public-private partnership and innovation intermediary is seeking an energetic and motivated life science professional for the role of an Entrepreneur-In-Residence (EIR) with product development experience and subject matter expertise in the fields of neurology and neuroscience. The EIR will reside within the National Institutes of Health (NIH) and will also support intramural and extramural initiatives on an as needed basis.

The EIR program was established at BioHealth Innovation to:

  • Retain and bring entrepreneurial talent to the Maryland ecosystem
  • Connect resources including institutions, technology assets, people and capital within Maryland that include federal institutions, labs, academic institutions, small businesses, disease foundations and the investor community
  • Build/support sustainable life science startups that will add value within the healthcare system and also build upon the existing infrastructure

The EIR will work with BHI leadership to ensure that the activities and outcomes are aligned with BHIs strategic focus.

EIR PROGRAM EXPECTATION

  • Identify commercially relevant life science technologies with specific focus on technologies to treat patients with Central Nervous System (CNS) disorders. These technologies include small molecule drugs, biologics and biotechnology products, and diagnostic and therapeutic devices.
  • Source/Identify early stage companies that require commercial and business development support.
  • Advise and support early stage companies by serving as an advisor or a part of the team to support the development of technologies and value creation.
  • Develop effective scientific collaborations between federal laboratories and agencies, universities, and the private sector
  • Support NIH initiatives (intramural and extramural) that are focused on supporting the commercialization of technologies
  • Participate in BHI strategic planning and development of entrepreneurial and educational programs

TECHNICAL EXPERTISE, ANALYSIS & EVALUATION

  • Serve as a scientific resource to the BHI-community on strategic technology development related to key programs, particularly in the area of CNS disorders
  • Represent the BHI vision of technology development to the research, small business, and technology development communities through individual interactions, workshops, special focus meetings, and presentations at national and international meetings
  • Serve as a resource for scientists and life science companies
  • Evaluate and analyze the effectiveness of short and long-term development and business strategies
  • Perform scientific and commercial analysis and coordination, including conducting comprehensive technical reviews of scientific studies, research, and analysis in the areas of advanced technology platform development for detection, diagnosis and treatment for a broad spectrum of therapeutic areas
  • Develop briefing documents, technical reports and detailed presentations for key stakeholders

OUTREACH & PARTNERSHIPS

  • Support building a community of motivated entrepreneurs and founders within the Maryland ecosystem including the federal laboratories.
  • Partner with economic development organizations and business associations to educate the small business life science community about potential areas of collaboration
  • Maintain contact with small business organizations, government agencies, scientists, and managers to exchange ideas

QUALIFICATIONS

  • Interest in working in a fast-paced environment
  • Sufficient scientific and product development skill set to analyze a breadth of innovations, with a particular focus on product development in CNS disorders
  • Strong organizational, analytical, communication skills
  • Ability to effectively liaise with internal and external key stakeholders
  • Demonstrated ability to multi-task and prioritize effectively and creatively
  • Maintain flexibility in a changing environment and communicate effectively across the organization
  • Excellent presentation skills and ability to lead a meeting and broker discussions
  • BA or BS in a scientific, health sciences or information technology field
  • Advanced degree in sciences or business (Ph.D., M.B.A., M.S.) a plus
  • Existing relationship with the investor community that includes angels, venture and strategic investors
  • Prior experience in life science product development and product strategy
  • Familiarity with the venture capital industry preferred
  • Personnel management experience preferred

TERMS & COMPENSATION

Compensation for this position is competitive and negotiable. BHI is an equal opportunity employer.

APPLICATION PROCEDURE

Interested applicants should send their resume and cover letter to Amanda Wilson at This email address is being protected from spambots. You need JavaScript enabled to view it.

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A surgeon can perform a complex, minimally invasive medical procedure with state-of-the-art robotic technology. But when she needs to communicate with her colleagues, the doctor is stuck with antiquated phone systems and outdated email clients.

When it comes to technology – not life-saving medical equipment, but the tools used in everyday communication – doctors are sometimes years behind the times. Despite rapid advances in technology (think smartphones, videoconferencing and more), physicians are largely reliant on slow, clunky and inconvenient tech.

Montgomery County ED

There have always been a lot of good reasons to locate a business in Montgomery County. 

Now there are 8 more.

Montgomery County Executive Isiah Leggett is pleased to announce the expansion of the county's innovative MOVE program.  Effective February 1, 2015, companies that sign their first three-year commercial lease in the county will receive a grant of $8 per square foot (sf).  Geared towards startups and businesses that locate into Montgomery County for the first time, the grant applies to companies that lease up to 10,000 sf. 

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Inova Health System has leased Exxon Mobil's Merrifield campus and plans to develop a multimillion-dollar Inova Center for Personalized Health, a major step toward becoming one of the world's foremost institutions in the fledgling field.

The Fairfax health system wrapped up negotiations Friday morning to lease the 117-acre campus across from its flagship hospital for the next 99 years with the right of first refusal to acquire the property. The deal comes roughly two years after Exxon Mobil retained real estate brokerage Cassidy Turley, now DTZ, to position the four-building, 1.2 million-square-foot property for a potential sale or redevelopment.

brain-sxc

The NFL, GE, and Under Armour officials announced that they have joined with the U.S. Department of Commerce's National Institute of Standards and Technology (NIST) to launch Head Health Challenge III, an open innovation competition to advance materials that better absorb or dissipate energy. These new materials could improve the performance of protective equipment for athletes, military personnel and those in dangerous occupations.

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University of Maryland School of Medicine (UM SOM) Dean E. Albert Reece, MD, PhD, MBA, and  Jeffrey A. Rivest, MS, President and Chief Executive Officer of University of Maryland Medical Center (UMMC), today announced the official launch of a new "Program in Lung Healing," that will further the School's position as a national leader in research, education and clinical innovation for acute ailments of the lung and respiratory system.

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Johns Hopkins University led the U.S. in higher education research spending for the 35th consecutive year in fiscal 2013, with $2.2 billion for medical, science, and engineering research, according to the National Science Foundation.

The university also once again ranked first on the NSF's separate list of federally funded research and development, spending $1.89 billion in fiscal year 2013 on research supported by NSF, NASA, the National Institutes of Health, and the Department of Defense.