The Institute for Bioscience and Biotechnology Research (IBBR) is interested in proposals to lease a bio-manufacturing facility configured to produce biologicals under cGMP conditions in compliance with FDA requirements for phase I/II clinical trials. The facility is also equipped to perform process development research, preclinical manufacturing for material necessary for IND-enabling toxicology studies, Point of Concept (POC) studies, and process demonstration in advance of GMP manufacturing. The Good Manufacturing Practices (GMP) facility is located on the University of Maryland's Shady Grove campus at 9600 Gudelsky Drive, Rockville, MD 20850.

It’s a familiar story: a biotechnology company develops a promising product but falls short of sales projections. The company then cuts staff, realigns resources, and turns to startups to fill its depleted pipeline.

While this scenario does play out in pharmaceuticals, it also describes what is happening in agriculture. Big ag companies face pressures to develop agricultural innovations and deliver financial returns. Agbio startups vie to fill big ag product pipelines. But even though motives driving agbio deals are similar to those in pharma, agbio startups can face steeper challenges.

CIITC provides a refundable income tax credit to Qualified Maryland Cybersecurity Companies (QMCCs) that secure investment from investors. The purpose of this new program is to incentivize and attract cybersecurity companies to startup in or move to Maryland; and to attract investment to cybersecurity companies in order to help them grow, create jobs and retain intellectual property in Maryland.

U.S. cities continue to reinvent themselves and demonstrate economic resiliency. While The University of Maryland-College Park (UMCP) has long had a reputation as a high-class research institution, its status has had a limited impact on the community surrounding it. With the evolving partnership between UMCP and the City of College Park, however, College Park is on the verge of becoming a hub for new innovation in the Washington, DC area.

Gov. Terry McAuliffe wants General Assembly budget leaders to find more money for economic development initiatives to fuel research into new technologies and allow him to use his executive authority to seal major business deals.

McAuliffe, in a letter Wednesday to budget negotiators for the House of Delegates and Senate, said his “primary area of concern, which I hope we can address together, is the restoration of the economic development proposals contained in my introduced budget.”

The Kansas Senate Ways and Means Committee heard testimony this week on a bill that would essentially sever financial ties between the state and the Kansas Bioscience Authority, according to the committee's vice chairman  Jim Denning, a Republican from Overland Park. 

“It’s unwinding it from any state influence and further state funding,” Denning says.

No cases of the Zika virus have originated in the U.S., but the possibility of it spreading north exists so doctors hope to get a better handle on the disease and work toward a cure.

"This virus has really exploded, transmitting throughout Central America, South America, and its arrival in the Americas, and the link to the congenital malformations has really caused concern that we're seeing today," said Dr. Lisa Maragakis with Johns Hopkins Infection Prevention.

What do breast cancer, lung cancer, and Zika virus have in common? They can all be treated with the same medications, claimed biotech billionaire Dr. Patrick Soon-Shiong at a genetics conference in San Diego on Thursday. The doctor doesn't shy away from bold statements based on preliminary data and was met with adoration as a kickoff speaker at the Future of Genomic Medicine conference—a science-heavy gathering at the Scripps Institution of geneticists, oncologists, data scientists, and other experts.

ide Group announced today that it will be awarding $25,000 worth of ide Group product design and development support for the best health innovation product idea pitched at the Building Better Futures for Health: A Product Design Challenge event.

Organised and hosted by ide Group, the event hopes to attract early stage entrepreneurs from across Australia with novel product ideas and technologies that have the potential to make a significant difference to people’s health. In response to alarming rises in health care costs and a rapidly ageing population, ide Group joins Australia’s push to find and invest in fresh, new ideas.

The Centers for Medicare and Medicaid Services finally is offering Meaningful Use-type incentives to long-term care, behavioral health and substance abuse care providers. It’s part of a wider effort to morph the electronic health records program into what acting CMS Administrator Andy Slavitt has said would be “something better” than Meaningful Use.

Coming soon to a hospital or clinic near you: dynamic healthcare pricing.

It’s not here yet, but Jay Deady, CEO of Recondo Technology, believes it’s on the way. He expects his revenue-cycle management company to enable the service. Healthcare providers will soon be able to offer different out-of-pocket prices depending on when and where each patient goes for a given service, he said.

Johns Hopkins University and MedImmune, the global biologics research and development arm of AstraZeneca, today announced a first-of-its-kind PhD training program between a major university and a biopharmaceutical company in the United States.

The Johns Hopkins-MedImmune Scholars Program, part of an ongoing collaboration between the university and biopharmaceutical company, will prepare JHU graduate students for careers in the biomedical workforce. Program participants will gain research experience in an industry environment, be introduced to the drug discovery and development process, and complete a yearlong internship at MedImmune.

The very reason United Therapeutics Corp. (NASDAQ: UTHR) exists is because there wasn't an effective treatment for Martine Rothblatt's daughter when she was diagnosed with pulmonary arterial hypertension more than 20 years ago.

Rothblatt recently told investors the Silver Spring-based pharmaceutical has found the market a bit more crowded these days. In December, the Food and Drug Administration approved Actelion Pharmaceuticals LTD's Uptravi to treat adults with pulmonary arterial hypertension.

March 29, 2016 2:30pm EST

Are you a small business, entrepreneur or scientist interested in technology-based agriculture innovations? Are you interested in collaborating with world class scientists? Then you should attend this webinar!

USDA ARS and the USDA SBIR program formed a partnership to encourage USDA SBIR applicants to develop research collaborations with ARS scientists and/or to license ARS technologies. The purpose is to increase the likelihood of success by providing both money and technologies to small U.S. businesses. The relevant language in the SBIR’s “Request for Application” states: "Additional factors that will be considered in the review process include whether an application involves a Cooperative Research and Development Agreement (CRADA) with a USDA laboratory, or a license to a USDA technology, or is a resubmission.”

The Venture+ Forum at HIMSS offered some insights from investors and entrepreneurs ranging from the predictable — patient engagement is oversaturated — to some surprising political insights on the eve of Super Tuesday. Here’s a look at some of the more interesting observations from the investor panels with a couple of entrepreneur insights as well.

Take MedCity's brief, confidential survey and share your insights on investment trends in life sciences and digital health.

Four Baltimore-area technology startups have received a total of $800,000 in loans from Anne Arundel County.

The county’s VOLT Fund, managed by the Anne Arundel Economic Development Corp., supports entrepreneurs and pre-revenue startups to help them reach key milestones, attract additional funding and grow locally. The fund receives $1.8 million a year from the state’s Small, Minority and Women-Owned Business Investment Fund, which is funded through video lottery revenue from Maryland casinos.

When March 30th from 5:00 p.m. to 7:00 p.m.

Where: Relevant Health 155 Gibbs St. #529 Rockville, MD 20850

Join us for an evening of networking around innovation and commercialization at the BioBuzz @ Relevant Health.  Meet with the organizations fueling commercialization in Maryland - BHI & TEDCO - and mingle with the first cohort of companies in the regions newest BioHealth accelerator - Relevant Health.

BHI, who operates the relevant health accelerator, is an innovation intermediary focused on commercializing market-relevant bio-health innovations and increasing access to early-stage funding. This is your chance to get to know some of their TEAM and Entrepreneur's in Residence to help you bring your product to market.

This event will be TEDCO's bi-monthly "meet the program managers" event. Take this opportunity mingle with the program managers and learn about how you can navigate through TEDCO's funding programs. TEDCO is State’s go-to resource for funding start-ups that need guidance as they bring innovative concepts to market..

WellDoc, a digital health technology leader, today announced a collaboration with LifeScan, Inc., a business within the Johnson & Johnson Diabetes Care Companies and a world leader in blood glucose monitoring, to deliver a best-in-class digital health solution for patients living with Type 2 diabetes. The agreement was facilitated with LifeScan affiliate Cilag GmbH International. In addition to the collaboration, Johnson & Johnson Innovation – JJDC, Inc. (JJDC) participated in WellDoc’s $29.5 million Series B financing.

University of Maryland, Baltimore President Jay A. Perman, MD, has been awarded the 2016 Giving Back Award from INSIGHT Into Diversity magazine, the largest and oldest diversity and inclusion publication in higher education. The Giving Back Award honors presidents and chancellors of colleges and universities who go above and beyond their everyday leadership duties and “give back” to their campuses and communities. Perman will be featured, along with 26 other recipients, in the April 2016 Leadership Support and Giving Back issue of INSIGHT Into Diversity magazine. 

Novavax Inc. is exploring its options in creating a Zika virus vaccine candidate.

So far, the Gaithersburg vaccine maker (NASDAQ: NVAX) has been mum about whether it would join other Greater Washington companies in the race to stop the Zika virus. The disease has caused concern among worldwide health leaders in recent months because of a suspected connection to birth defects in newborns and Guillain-Barré syndrome in adults.

If you want to find something quickly, knowing what not to look for can help speed up the process, researchers say.

New research from Johns Hopkins University has found that the art of ignoring can be used to improve search performance, but only after people have been given time to practice.

Tech 2000, Inc. (Tech 2000), a leading education technology and solutions company, has added two new directors to its board of directors, Bruce Klein and Paul Opalack.

“Adding these two technology rockstars to our board will help us aggressively expand Tech 2000, as well as our appnetic and Lumious enterprise software businesses,” said Tien Wong, CEO of Tech 2000. Klein and Opalack will help shape future strategy for not only Tech 2000’s core business of corporate learning and development, software development, and learning tools and analytics, but also the company’s two software as a service (SaaS) businesses: sales acceleration platform appnetic, and learning analytics platform Lumious.

The health foundation of Microsoft billionaire Bill Gates is in talks with Latin American governments and scientists over plans to spread hundreds of millions of mosquitoes that are unable to transmit dengue fever and Zika virus.

The discussions include a proposal by scientists in Medellín, Colombia, to spend $16 million to try to protect the city’s three million people with the new breed of mosquitoes.

Funding and Research Opportunities The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:

Notices:

• NIHs Implementation of the Federal Awardee Performance and Integrity Information System (FAPIIS) Requirements
• (NOT-OD-16-067) 
• National Institutes of Health
• Requirement for the Appropriate Signatures on NIH Forms and Official Documentation
• (NOT-OD-16-071) 
• National Institutes of Health
• Notice of Correction to RFA-HL-16-020 "Limited Competition: Small Grant Program for NHLBI K01/K08/K23 Recipients (R03) “
• (NOT-HL-15-298)
• National Heart, Lung, and Blood Institute
• Notice of Intent to Publish a Funding Opportunity Announcement for Investigator-Initiated Multi-Site Clinical Trials: Clinical Coordinating Center (UG3/UH3)
• (NOT-HL-16-303)
• National Heart, Lung, and Blood Institute
• Notice of Intent to Publish a Funding Opportunity Announcement for Investigator-Initiated Multi-Site Clinical Trials: Data Coordinating Center (U24)
• (NOT-HL-16-304)
• National Heart, Lung, and Blood Institute
• Stimulating Peripheral Activity to Relieve Conditions (SPARC): Pre-clinical Development of Existing Market-approved Devices to Support New Market Indications (U18)
• (RFA-RM-16-009)
• NIH Roadmap Initiatives
• National Center for Advancing Translational Sciences
• Application Receipt Date(s): May 02, 2016

Wednesday, March 9, 2016 from 3:30 PM to 5:00 PM (EST)

Montgomery County Department of Economic Development - 111 Rockville Pike Suite 800 Rockville, MD 20850

The National Oceanic and Atmospheric Administration (NOAA) is based on Silver Spring, MD, but is served by laboratories and science centers across the country.  From severe weather and climate to ocean and coastal sciences, NOAA's work is extremely varied and offers a number of opportunities for MD companies.  This presentation from NOAA's Technology Partnerships Office will provide an overview of NOAA's science activities, as well as ways private sector companies can work with NOAA.  

Biohealth is all over the map in Maryland. There’s the biotech corridor in Montgomery County, where companies like MedImmune LLC and Emergent BioSolutions Inc. call home. The students and academic researchers at Johns Hopkins and University of Maryland are up in Baltimore. Then there are the government agencies and their many, many contractors spread throughout the Baltimore-Washington region.

Chris Frew wanted to find a way to connect all the dots.

Enter BioHive, an online community engagement website for the movers and shakers of biohealth.

The week of April 3-9 Paul Singh, a successful entrepreneur and seed-stage investor, will visit Los Alamos, Taos, Santa Fe and Albuquerque to deliver a week-long series of events for aspiring entrepreneurs and community members.

China will develop traditional Chinese medicine (TCM) into a pillar industry, according to a blueprint released by the State Council, China's Cabinet, on Friday.

The plan proposes universal access to TCM care by 2020. By 2030, TCM should make a notably greater contribution to social and economic development.

In 2011, when the University System of Maryland Board of Regents was considering a merger of the College Park and Baltimore campuses of the University of Maryland, we supported the idea. The pure-research-focused flagship in College Park and the professional school campus in Baltimore had little combined activity and were missing key potential opportunities for cross-disciplinary scholarship and teaching and for economic development. Given how crucial the knowledge economy is to Maryland's future, we urged leaders to look past parochial concerns and take advantage of the opportunities a combined university could provide.

Opdivo from Bristol-Myers Squibb ($BMY) followed Merck's ($MRK) Keytruda onto the market, but the immuno-oncology drug quickly overtook its rival and has never looked back. It just today won recommendations in Europe for two more indications. But while it leads the race, analysts say there are still opportunities for Keytruda and drug candidates from others to close the gap in a market that is projected to reach $40 billion in annual sales.

Fast Company magazine recently named the Johns Hopkins Applied Physics Laboratory as one of the world's most innovative companies of 2016 for building the bionic man, one arm at a time.

The publication highlighted APL's DARPA-funded Revolutionizing Prosthetics program and specifically recognized its breakthrough Modular Prosthetic Limb project, which is the world's first artificial limb controlled by neural impulses.

Health Datapalooza is a national conference focused on liberating health data, and bringing together the companies, startups, academics, government agencies, and individuals with the newest and most innovative and effective uses of health data to improve patient outcomes.

Business Innovation Network startup Nexercise owners Ben Young and Greg Coleman struck a deal with investor Mark Cuban for $1.5 million in exchange for 10% equity stake in the company and $1.5 million unsold advertising inventory in credit. Their app Sworkit is in the number one position in the Apple store for health and fitness and was a recent featured story on Washington Business Journal's website.

Rani Therapeutics, headquartered in San Jose, Calif., announced it had closed on its latest funding round, now totaling more than $70 million. Existing investors included Novartis (NVS), Google Ventures, Buttonwood, GF Ventures, KPC Pharmaceuticals, inCube Ventures and VentureHealth. New investors include AstraZeneca (AZN), Virtus Inspire Ventures, and Ping An Ventures. Rani focuses on a development platform to allow biologic drugs that are typically injected to be taken orally. Drugs that fall into this category include TNF-alpha inhibitors, interleukin antibodies, basal insulin and GLP-1.