Biohealth Innovation
Register Now for the 6th Annual BioHealth Capital Region (BHCR) Forum held on April 14-15 at AstraZeneca in Gaithersburg, MD. Join your peers biotech and life science executives and expert speakers from industry, academia, healthcare, government, finance and real estate development, among others, converged to discuss the BHCR’s path forward to becoming a top three U.S. biotech cluster by 2023.
Register Now for the 6th Annual BioHealth Capital Region (BHCR) Forum held on April 14-15 at AstraZeneca in Gaithersburg, MD. Join your peers biotech and life science executives and expert speakers from industry, academia, healthcare, government, finance and real estate development, among others, converged to discuss the BHCR’s path forward to becoming a top three U.S. biotech cluster by 2023.
Submit your application for a change to be named the Startup Company with the Most Commectial Potential at the BHCR Forum, win $10,000 and more!
Here’s a list of our upcoming events. Get them on your calendar so you don’t miss anything.
When a Canadian company called Deep Genomics announced in September that it had used artificial intelligence to solve a long-standing mystery about a genetic disorder called Wilson’s disease—and, what’s more, had used another deep-learning platform to identify a potential treatment—there was a flurry of excitement in the drug development world. The apparent milestone, which the company hailed as the “first-ever A.I.- discovered therapeutic candidate,” got echoing headlines from dozens of news outlets, and in January, the five-year-old startup received a $40 million endorsement in the form of a fresh round of venture capital funding.
Image: JAMIE CHUNG—TRUNK ARCHIVE - https://fortune.com
Patient concierge startup HelpAround has nabbed $6 million to help people with chronic diseases stick with their treatment.
The Bethesda company, whose mobile platform connects patients with resources for the drugs they’re prescribed, is pushing deeper into the specialty pharmacy arena — where medications are high-cost and complex — after focusing first on the diabetes and renal disease space. The business is now partnering with these drug manufacturers to keep patients from dropping out of their treatment plans, especially those who have been newly diagnosed.
Image: Yishai Knobel is co-founder and CEO of HelpAround. HELPAROUND
The National Capital Consortium for Pediatric Device Innovation (NCC-PDI), in collaboration with MedTech Innovator, is now accepting applications for its showcase pitch event on March 23, 2020 in College Park, Maryland. The competition is focused on pediatric devices in three areas of critical need: Cardiovascular, orthopedic and spine, and neonatal intensive care unit (NICU).
Metro Boston experienced a year-over-year increase of 8% in life sciences employment through the third quarter, NKF’s Liz Berthelette reported, citing data from JobsEQ by Chmura. That led to the second consecutive year of absorption exceeding one million square feet for lab space, and the market ended 2019 with 5% vacancy, a new low.
Image: https://www.connect.media/
More Funding in Phase I –
We posted new Phase I funding opportunities for small businesses (Small Business Innovation Research and Small Business Technology Transfer). The Phase I award amount increased from $225,000 to $256,000.
Project Pitch Update –
The Project Pitch allows startups and small businesses to get quick feedback at the start of their application for Phase I funding. Each company can only submit one Project Pitch at a time and up to two Project Pitches per submission window (see dates below). Once invited, a Pitch expires after a year. For more information, please refer to the updated Frequently Asked Questions.
A Bedford-based nonprofit, MITRE, is the powerhouse beyond a new initiative called Bridging Innovation, designed specifically to play matchmaker between startups and government agencies.
For the program, MITRE has partnered with essentially all of Massachusetts’ major players: MassRobotics, MassChallenge, Gov. Charlie Baker’s cybersecurity advisory panel, the Massachusetts Military Asset Task Force, Techstars’ Air Force Accelerator, Harvard Innovation Labs, MIT Engine and the UMass Lowell Innovation Hub.
AstraZeneca plans to invest $520 million in its manufacturing site in Dunkirk, France, over the next five years and create roughly 150 jobs, Bloomberg reported.
Of the total, $230 million will be dedicated to building assembly lines and modernizing the drugmaker's equipment in the Dunkirk facility, which focuses on developing and manufacturing asthma treatments. The new lines could create about 100 highly skilled jobs, according to Bloomberg.
Psychedelic drugs—once promising research subjects that were decades ago relegated to illicit experimentation in dorm rooms—have been steadily making their way back into the lab for a revamped 21st-century-style look. Scientists are rediscovering what many see as the substances’ astonishing therapeutic potential for a vast range of issues, from depression to drug addiction and acceptance of mortality.
Johns Hopkins University is blowing up its business-school curriculum.
Starting in the fall of 2020, the university’s traditional two-year master’s of business administration degree will take a hard turn toward health, with a particularly heavy focus on quant skills, from exposure to coding to data analysis, said Alexander Triantis, dean of the Carey Business School.
Image: Brian Gunia, an associate professor at the Carey school, plans to tweak aspects of his class to fit the new health and analytics focus. PHOTO: MATT ROTH FOR THE WALL STREET JOURNAL
How has a health system with a 323-bed hospital and a three-person innovation team built connections with more than 100 startups around the globe and attracted a Johnson & Johnson innovation lab to collocate on its campus? And how does it simultaneously challenge its own academic faculty to tackle the quandary of pediatric device innovation?
We are pleased to announce that Dr. Monica Lopez returns this year to the Electronic Imaging International Symposium in Burlingame, CA as both a keynote speaker for the Autonomous Vehicles and Machines 2020 conference and course instructor.
The federal government has tapped a local company to help defend against superbugs.
Gaithersburg’s Adaptive Phage Therapeutics Inc. has earned a $10.2 million contract with the Department of Defense to help advance PhageBank, APT's collection of viruses that target specific pathogens and kill drug-resistant bacteria. The ultimate goal is to make its therapy for drug-resistant infections available to the U.S. military and the public, APT said Wednesday.
Image: Dr. Carl Merril, third from right, with his son Greg, CEO and co-founder of Adaptive Phage Therapeutics, and other members of the team. ADAPTIVE PHAGE THERAPEUTICS INC.
China’s viral outbreak is straining the resources of front-line hospital staff in epidemic-stricken Wuhan, who have been forced to turn away patients because of a lack of beds and basic medical supplies.
Image: Chinese authorities are building a new hospital in the city of Wuhan following the outbreak of a virus that has infected more than 800 people and killed 26, aiming to complete it within six days. Photo: CCTV
About a month into the new gig, the former investment banker is nailing down her priorities for this year. On her list: Improving access to capital.
Image: Allyson Redpath is the Maryland Department of Commerce’s new director of entrepreneurship and small business. JOANNE S. LAWTON
The American Association for the Advancement of Science (AAAS) awarded its 2019 Newcomb Cleveland Prize to University of Maryland entomologists Raymond St. Leger, Brian Lovett and their seven West African collaborators.
The prestigious award is given to the authors of the most impactful paper published in AAAS's flagship journal Science during the previous year.
Image: CREDIT: ETIENNE BILGO
The Precision Medicine World Conference (PMWC) is an independent and established conference series considered to be the preeminent precision medicine conference that attracts recognized leaders, top global researchers and medical professionals, and innovators across healthcare and biotechnology sectors to showcase practical content that helps close the knowledge gap between different sectors, thereby catalyzing cross-functional fertilization and collaboration. Since 2009, recognized as a vital cornerstone for all constituents of the health care and biotechnology community, PMWC provides an exceptional forum for the exchange of information about the latest advances in technology (e.g. DNA sequencing technology), in clinical implementation (e.g. cancer and beyond), research, and in all aspects related to the regulatory and reimbursement sectors.
Alexandria LaunchLabs™ in Maryland, will provide fully equipped, affordable laboratory/office space with flexible lease terms, supporting infrastructure, access to amenities, and supporting services and programming through the project’s consortium of world-class partners, including Alexandria Venture Investments, BioHealth Innovation, Montgomery County, and the City of Gaithersburg. This unique, startup environment will accelerate the growth of local early-stage life science companies.
Hilden, Germany, and Germantown, Maryland, January 9, 2020 – QIAGEN N.V. (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced the 2,500th placement of QIAsymphony, the leading Sample to Insight workflow automation solution for molecular laboratories worldwide, in Tübingen, Germany.
Cenata GmbH is a medically led genetic diagnostic laboratory offering prenatal testing, and repeat customer of the QIAsymphony, purchasing this milestone QIAsymphony SP as the third unit in their lab, expanding capabilities for circulating DNA purification and other applications.
Emmes today announced that the U.S. Food and Drug Administration (FDA) has approved a prescription-only medical device used to estimate the weight of infants who are up to 90 days of age.
The Mercy babyTAPE is a tape-measure-like device that permits health care professionals to estimate the body weight of preterm and full-term infants when a scale may not be available or practical to use. Accurately estimating pediatric patient weight is important for drug dosing, resuscitation interventions, and nutritional assessments. This easy-to-produce device could be especially useful in emergency or resource-constrained situations such as remote or rural areas, and in developing countries.
GAITHERSBURG, Md., Jan. 13, 2020 (GLOBE NEWSWIRE) -- Emergent BioSolutions Inc. (NYSE:EBS) announced that it has received agreement from the European Medicines Agency (EMA) to pursue its proposed development plan for its chikungunya virus virus-like particle (CHIKV VLP) vaccine candidate. The company has proposed conducting a safety and immunogenicity Phase 3 trial using Serum Neutralizing Antibodies (SNA) as an immune correlate of protection to predict clinical benefit of the vaccine candidate.
“Emergent is encouraged by the concurrence we have received from EMA in paving the path for chikungunya vaccine development based on SNA as the surrogate endpoint,” said Abbey Jenkins, senior vice president and vaccines business unit head at Emergent BioSolutions. “As a leading provider of travel health vaccines, Emergent seeks to address the threat posed by this highly debilitating virus by defining a realistic and optimal path to bring to market a much-needed chikungunya vaccine that could potentially serve patients worldwide. We look forward to continuing to work with regulators, including the U.S. Food and Drug Administration (FDA) with whom we had our End-of-Phase 2 meeting last December, as we plan to initiate a pivotal Phase 3 trial this year and define the approach for a post-approval confirmatory efficacy trial.”
When Robert Lord cofounded Protenus with Nick Culbertson in 2014, it required choosing to put medical school on hold. After six years and plenty of growth at the Fells Point-based healthcare analytics company, Lord is returning to Johns Hopkins this month to complete training to become a physician. With that move, he will transition from a day-to-day leadership role to chairman of the board. The transition has been in the works for several months, and his responsibilities were apportioned across the company in that time.
Image: Protenus cofounder Robert Lord. (Courtesy photo)
Engineered Medical Systems, Longeviti Neuro Solutions and The LaunchPort™ announced today that they have entered into an agreement to place new, low temperature, low toxicity hydrogen peroxide sterilization capacity at The LaunchPort™/EMS facility in Port Covington. The systems are being procured by Longeviti to support the Maryland production of their Low-profile Intracranial Devices (L.I.D.) platform. The Longeviti L.I.D. Platform has led to several innovative FDA cleared products thus far, the ClearFit and InvisiShunt, and more are in development. The systems will be operated by Engineered Medical Systems within EMS’s regulated medical manufacturing facility at LaunchPort™. These new systems are expected to have completed initial validations by the end of Q1 2020.
Image: https://www.prweb.com
Herndon, VA, Jan. 14, 2020 (GLOBE NEWSWIRE) -- The Center for Innovative Technology (CIT) today released the 2019 CIT GAP Funds Impact Report, detailing both return on investment and socio-economic impact made since the fund’s inception in 2005. A family of funds placing equity investments in Virginia’s high-growth based technology, life science, and cleantech companies at the earliest developmental stages, CIT GAP Funds has deployed $28.8 million in capital across 223 investments. CIT GAP Funds investment leadership has attracted national recognition and continues to demonstrate why CIT has been named Virginia’s Most Active Investor for the last five years by CB Insights.CIT GAP Funds has yielded four times their capital invested across Tech Fund “Roadmap” investments in cybersecurity, data analytics, enterprise software and deep tech sectors and helped position the fund for return of all capital deployed. The report highlights several other figures that capture the overall impact CIT GAP Funds has on the Commonwealth, including:
Image: https://www.streetinsider.com
The seller converted the office space — leased heavily by local biotech companies — to lab suites, then sold the buildings just three years after buying them.
Image: The buildings at West Watkins Mill Road and Clopper Road collectively sold for $53.25 million. COURTESY TRITOWER FINANCIAL
The BioHealth Capital Region (BHCR) experienced significant change in 2019 that has set the table for an intriguing 2020.
How 2020 plays out across the region is unknown.
However, if you’ve followed BioBuzz throughout the past year, it is abundantly clear that workforce development strategy, investment, and support will be a critical issue for the next decade in the BHCR. In addition to change and growth across more traditional life science sectors, the ascension of personalized medicine within the region, which includes a host of new and growing regenerative medicine, cell therapy, and gene therapy companies, has transformed the region’s workforce needs.
A Baltimore business incubator has been named among the best in the world.
Emerging Technology Centers in Baltimore has been recognized by UBI Global as one of the 10 best public business incubators in the world.
The ranking was created based on a world benchmark study that included a total of 1,580 programs worldwide assessed on 21 key performance indicators including economy enhancement, talent retention, access to funds, post-graduation performance of companies and more to create lists of the top university, public and private incubators.
Image: The ETC is located at the King Cork & Seal building in Highlandtown. CONTROL TEC INC, & METRO DEVELOPMENT LLC
LOS ANGELES, Jan. 15, 2020 /PRNewswire/ -- USA News Group – A new study published in the journal Molecular Therapy reports that researchers found a drug used in the treatment of HIV that may also suppress Zika virus infection. Zika virus disease is caused by a virus transmitted primarily by Aedes mosquitoes, which bite during the day.
Research and developments with multidisciplinary approaches are proving vital to the treatment and defense against viral and infection diseases as they become more aggressive and deadly. Companies preparing to offer new treatments to deal with the onslaught may become some of valuable over the next decade. Leaders in this space are anticipating strong revenue from collaborations including NGM Biopharmaceuticals Inc. (NASDAQ: NGM), Emergent BioSolutions Inc. (NYSE: EBS), and SIGA Technologies, Inc. (NASDAQ: SIGA)
SAN FRANCISCO—Roche has inked a 15-year partnership with Illumina in oncology, which will include collaborating on new companion diagnostic indications for the DNA sequencing giant’s pan-cancer assay.
Announced during the J.P. Morgan Healthcare Conference, the nonexclusive pact will also enable Roche to develop and distribute in vitro diagnostic tests for Illumina’s current and future hardware lines—such as the NextSeq 550Dx and the upcoming NovaSeqDx system. The deal’s financial terms were not disclosed.
Image: Roche and Illumina, as well as Roche's Foundation Medicine division, will work to secure regulatory approvals for Illumina’s TruSight Oncology 500 assay as a pan-cancer companion diagnostic for different targeted therapies. (Illumina)
GERMANTOWN, Md., Jan. 6, 2020 /PRNewswire/ — Precigen, Inc., a biopharmaceutical company specializing in the development of innovative gene and cellular therapies to improve the lives of patients, today announced that the US Food and Drug Administration (FDA) has granted orphan drug designation (ODD) to PRGN-3006, a first-in-class investigational therapy using Precigen’s non-viral UltraCAR-T™ therapeutic platform for patients with relapsed or refractory acute myeloid leukemia (AML) (clinical trial identifier: NCT03927261). Precigen announced in Q3 2019 that it had completed enrollment for the first cohort of this clinical trial and expects an initial data readout in the second half of 2020.
The National Institute of Standards and Technology is seeking public feedback on its plan to revamp the Interagency Edison (iEdison) System, an online portal where companies that receive federal government funding report their inventions.
The project is part of NIST’s increased focus on federal technology transfer as part of the Lab-to-Market Cross-Agency Priority Goal under the President’s Management Agenda. Every year the federal government invests more than $100 billion in research and development, and in return grantees report the inventions that come out of this funding to the government through iEdison.
The Maryland Department of Commerce has created a new role focused on the state's startup ecosystem and tapped a former investment banker and angel investor to head up the effort.
Allyson Redpath, who previously worked at Citigroup and Goldman Sachs, started as the department's entrepreneurship director on Dec. 18, Secretary Kelly Schulz announced Thursday. In her new role, Redpath will work to attract and retain early-stage companies in Maryland. She will also help facilitate connections between these businesses and available resources, such as access to capital, company counseling and other small business workshops and events.
Image: Joanne S. Lawton
