Biohealth Innovation
Johns Hopkins University has an acceptance rate under 20 percent. It’s clearly a prestigious institution. But what is it like to interview for a job at the region's largest private employer?
I hit the books hard to go through Glassdoor’s index of user-submitted interview questions. Here are the three geekiest interview questions asked at Johns Hopkins (pertaining to different jobs, of course). Take a moment to see if you can answer them.
Social networks have been all “abuzz” over the past month getting the vote out for the most important elected-position in the region.
No … silly … we are not talking about elected officials in our neighboring Commonwealth, we are talking about what really matters — the Pitch Across Maryland 2.0!!!
Today is the day we tallied the view-votes for the “Fan Favorite” competition of the Pitch Across Maryland.
GSK has selected eight winners in its first Discovery Fast Track competition, designed to translate academic research into starting points for new potential medicines. The contest attracted 142 entries across 17 therapeutic areas from 70 universities, academic research institutions, clinics and hospitals in the US and Canada.
The winning projects show clear opportunities to deal with important unmet medical needs, including antibiotics resistance, diseases of the developing world and certain cancer types. The selected scientists will collaborate with GSK’s Discovery Partnerships with Academia (DPAc) team, the sponsor of the competition, to rapidly screen and identify novel compounds to test their promising hypotheses. If advanced chemical testing is successful, the winning investigators could be offered a DPAc partnership to further refine molecules and assess their potential as novel new medicines.
Okay. The verdict’s still out on loud. (If my family–myself included–is any indicator, that’s probably a losing battle.) The point is our human capital is plummeting globally thanks to our poor health, according to the World Economic Forum’s new Human Capital report. Our obesity and fast-paced lives are bound to catch up with us with heart disease and diabetes among other chronic disease. But it could come around and kick us where it collectively hurts the most: our already hurting economy.
After the trip UNN participants were interviewed and filled the Feedback forms (see the Appendix). The results of interviews and feedback forms processing may be summarized as follows.
State government agency expenditures for research and development totaled $1.404 billion in FY 2011, an 11.3% increase over the $1.261 billion reported in FY 2010. Expenditures for R&D facilities (construction projects, major building renovations, and land and building acquisitions intended primarily for R&D use) totaled $109 million in FY 2011, a 1.7% increase over the $107 million reported in FY 2010. This InfoBrief presents summary statistics from the FY 2010 and FY 2011 Survey of State Government Research and Development, sponsored by the National Science Foundation (NSF).
The FY 2010 and FY 2011 survey presents the most recent NSF statistics of R&D activities performed and funded by state government agencies in each of the 50 states, the District of Columbia, and Puerto Rico. Survey data are available by state and by individual state agency. For the first time, NSF collected two fiscal years of data from state governments as part of a single survey operation. In addition, a new category was added to this survey, so state agencies were given the option to separately classify their energy-related R&D expenditures. Other R&D categories include agriculture, environment and natural resources, health, transportation, and other.
Now on its sixth run, the Research Commercialization Introductory Course is a very popular online course designed to help science and engineering researchers better understand how research commercialization works. Over 5000 students, faculty and researchers from across the US have taken this course since it's been offered.
Research commercialization involves taking articles, documentation, know-how, patents, and copyrights, which are created during research activities and getting them to users and patients for real societal impacts. In some cases, commercialization involved taking patents based on the research and licensing them to a company. This usually involves also having the researchers consult to the company. In other cases, commercialization involves forming of creating a startup and applying to federally funded commercialization programs. In all cases, though, research commercialization typically involves defining the nature of the research being commercialized (e.g., in a patent or intellectual property agreement), establishing a commercial relationship with another party (e.g., employment, a sale or license), and negotiating a contract (e.g., compensation).
Emergent BioSolutions Inc. presented preclinical data on its lead bispecific Adaptir therapeutic, ES414, at the 5th Annual Protein and Antibody Engineering Summit (PEGS) in Lisbon, Portugal. The ES414 molecule was constructed using Emergent’s Adaptir technology platform and is being developed as a potential therapeutic for metastatic castration-resistant prostate cancer (mCRPC).
The presentation shared results of preclinical studies demonstrating ES414 is pharmacologically active and well tolerated. Preclinical in vitro and in vivo studies have shown ES414 redirects T-cell cytotoxicity (RTCC) towards prostate cancer cells expressing prostate specific membrane antigen (PSMA), an antigen commonly found on prostate cancer cells. The ES414 molecule selectively binds and links the T cell receptor on cytotoxic T cells to the PSMA on tumor cells, triggering tumor cell destruction.
Newly-minted MBA graduates are more frequently turning away from finance jobs as financial crisis aftereffects linger and instead picking careers in the tech sector.
In fact, for the first time, more Stanford Graduate School of Business grads this year chose tech jobs over finance jobs, The Wall Street Journal reports. Thirty-two percent of this year's class picked tech while 26 percent headed into finance — those figures were 13 percent and 36 percent, respectively, two years ago.
BD Diagnostics, a segment of BD (Becton, Dickinson and Company), a leading global medical technology company, announced today at EUROGIN 2013 that the Company has achieved CE/IVD marking of its BD Totalys(TM) MultiProcessor, an automated instrument that integrates the pre-processing for the BD SurePath(TM) Liquid-based Pap Test with a molecular aliquot, maintaining sample integrity while improving efficiency in the lab. The Company also supported a symposium at the conference which highlighted the performance of the new BD Onclarity(TM) HPV Assay on the BD Viper(TM) LT System, which is pending EU certification.
"These new products are part of BD's integrated Women's Health portfolio and support full sample chain of custody, high diagnostic accuracy and a clear patient management approach - all important elements to improving patient care," said Paul Holt, Global Market Segment Leader, Women's Health & Cancer - BD Diagnostics. "When laboratories and physicians partner with BD Diagnostics, they benefit from highly customized, leading-edge solutions for the rapidly changing landscape of cervical cancer screening."
Wednesday, Nov. 20, 2013, Southeastern Universities Research Association
In 2010, the University of Virginia created a pan-university innovation initiative designed to elevate innovation, entrepreneurship, and translational research as core competencies and key strategic priorities of the institution. A long-time practitioner of “traditional technology transfer”, UVa sought nothing less than a “sea change” in its innovation ecosystem and culture in creating this new innovation platform. Intellectual property is still protected, marketed and licensed (i.e., “traditional technology transfer”). But beyond these activities, the university has nurtured an ecosystem (both within the institution and beyond) which can be leveraged to identify innovation and knowledge assets more broadly and earlier; to advance those assets through proof-of-principle and commercial relevance assessments; and to leverage such assets and relationships to create products, services, companies, and jobs – and value for the university. Along the way, UVa Innovation actively uses its research capacities, social media, crowd-funding, grand challenge competitions, outreach and networking, and relentless “innovation proselytizing” to engage increasing numbers of university students, faculty, staff, administrators, alumni, and supporters in elevating innovation as core competency and focal point of UVa’s mission.
The University of Maryland BioPark announced today that the Clinical Trial Center for Functional Foods (CTCF2) has signed a lease for office space at the BioPark. The main home for the CTCF2 is located in the Jeolla-buk Province of South Korea, and is part of the Chonbuk National University Hospital.
“When the BioPark was founded, we had the goal of establishing a strong presence from the international life sciences community,” said Jane Shaab, University of Maryland Research Park Corporation Senior Vice President and Executive Director of the UM BioPark. “We began building this presence with the SNBL Clinical Pharmacology Center, which is a wholly owned subsidiary of a Japanese biomedical company, and now we have our first investor from Korea.”
Nearly 6,000 people took part in the second annual Baltimore Innovation Week at the end of September, in partnership with many great organizations throughout the region. Full disclosure, we at Technical.ly Baltimore helped lead the big open calendar of events. Find a wrap video and some outcomes of the week below. This year, we saw […]
The Johns Hopkins University Applied Physics Laboratory (APL) will hold its second annual Parent STEMpowerment Workshop on Nov. 17, in the Kossiakoff Center on its Laurel, Md. campus. The free workshop, from 2 p.m. to 5 p.m., is designed to help parents of elementary and middle school students prepare their children to explore careers in science, technology, engineering and math (STEM).
The event, developed for parents with little or no exposure to STEM fields, will provide resources to support children in the pursuit of STEM careers and impart a better understanding of the importance of STEM.
Furthering a commitment to bilateral innovation, a delegation of five biomedical and information technology companies from the University of Nizhny Novgorod visited the University of Maryland on October 16-25 under the auspices of the U.S.-Russia Innovation Corridor. The companies participated in the first region-to-region visit of Russian startups under the program since UMD and UNN signed a Memorandum of Understanding in April 2013 to deepen ties in the biomedical industry.
A merger of the University System of Maryland and the Southern Maryland Higher Education Center is one step closer after leaders signed an agreement this month for a new building at the California campus.
A merger could open up educational and business opportunities for the region, officials said Friday during a signing agreement at the Chesapeake Biological Laboratory in Solomons.
The increasing digitization of healthcare could shake up the industry in many ways, from allowing doctors to do their jobs more efficiently to reducing demand for specialists, according to a new study from the Johns Hopkins Bloomberg School of Public Health.
How technological changes will increase access and improve quality of care is still a moving target, however, according to the new study, published today in Health Affairs. Meanwhile, a different set of researchers found that one technological intervention improved access to care for depression, but had no impact on depressive symptoms.
GSK today announced the recruitment of 140 new apprentices over the next two years in the UK – of which a third will be in engineering. This represents a 27% increase in the company’s annual intake of apprentices since 2012/13.
GSK also announced plans to increase the number of engineering graduate trainees by 26 in Britain – an increase of 25% since 2012/13.
DreamIt Health, a new health startup incubator that paired entrepreneurs around Philadelphia with experts from Independence Blue Cross and Penn Medicine to help commercialize new ideas, is now venturing down I-95 to expand into the city of Baltimore. We spoke with Elliot Menschik, MD, PhD, who manages DreamIt Health, about the goals of the new venture and the opportunities it plans to offer to Baltimore’s medtech entrepreneurs.
Another massive acquisition by MedImmune and a new fund to uncover the next ARM lit up a vibrant October when deals in the Cambridge UK technology cluster topped $900 million.
It took the seventh month total in Business Weekly’s Cambridge Cluster Deals Digest to just over $23 billion. While MedImmune splashed the most cash, it was a home-grown innovation that had the Cambridge investment community buzzing.
Attend the last DreamIt Health information sessions on Tuesday, November 5, 2013 from 6:00 pm - 7:00 pm at the Johns Hopkins Brain Science Institute and Wednesday, November 6, 2013 from 5:30 pm - 7:30 pm at the Johns Hopkins University Montgomery County Campus.
DreamIt Health is a health tech accelerator that helps startups achieve in four months what might otherwise take years to accomplish. The program has helped launch 130 IT companies to date.
DreamIt Managing Partner Elliot Menschik will present on November 5 and BioHealth Innovation’s Ethan Byler will present on November 6. These free programs will answer questions about Dreamit, and lite fare will be provided.
GrayBug LLC, a startup ophthalmic drug company spun out of Johns Hopkins University’s Wilmer Eye Institute, has hired its first full-time CEO and raised $1.5 million in new venture capital funding.
Michael O’Rourke, a veteran pharmaceutical industry executive and consultant, joined Baltimore-based GrayBug on Oct. 15. He comes to the company as it closed $1.5 million in funding from investors including the Maryland Venture Fund, the Abell Foundation and Brown Advisory, the Baltimore asset management firm.
Johns Hopkins Montgomery County Campus Executive Director Elaine Amir retired Sept. 30. On an interim basis, Leslie Ford Weber is serving as campus executive director.
Leslie knows her way around Johns Hopkins and Montgomery County. She is director of government and community affairs for Montgomery County, representing both the university and the Johns Hopkins health system in their interactions with county elected officials, businesses and other external organizations. Before joining Government and Community Affairs, Leslie held a dual role as executive vice president of the Suburban Hospital Foundation and senior vice president of Government and Community Relations for Suburban Hospital.
Type 2 diabetes is viewed as one of the biggest drivers of healthcare costs partly because of the complications that can arise from the condition. Diabetes costs in 2012, for example, reached $245 billion. One complication — hyperglycemia – can cause diabetic coma if it remains untreated. WellDoc is working on a way to predict hyperglycemia without patients needing to have continuous glucose monitoring. The plan is to add the mhealth tool to its prescription mobile app platform Bluestar, which the company is preparing to roll out.
It presented positive findings from a study of the hyperglycemia prediction tool at the Diabetes Technology meeting in San Francisco this week, according to a company statement.
Vaccine manufacturers are often criticized for investing in shots aimed at high-margin Western markets, while neglecting diseases affecting the developing world. This week, the Bill & Melinda Gates Foundation set up a project to spur development in neglected areas by cutting the financial risk of early research.
GlaxoSmithKline ($GSK) and Sanofi ($SNY) are the first companies to sign up to the project, called the Vaccine Discovery Partnership (VxDP). Under VxDP, the Gates Foundation will work directly with biopharma companies on projects that further its goals and span from preclinical through to Phase IIa. By providing financial support for the projects, the Gates Foundation hopes to make early-phase vaccine research a less risky proposition for the industry.
Fidelity Biosciences and REGENX Biosciences today announced the formation of Dimension Therapeutics, a gene therapy company focused on developing novel treatments for rare diseases. Dimension will focus on advancing its platform of gene therapy programs in rare diseases through clinical development, starting with lead programs in hemophilia, and building out a world-class product engine for AAV therapeutics. Dimension has completed an undisclosed Series A financing led by Fidelity Biosciences.
In conjunction with its launch, Dimension has entered into an exclusive license and collaboration with REGENX. REGENX holds exclusive rights to a portfolio of over 100 patents and patent applications pertaining to its NAV® vector technology that includes novel AAV vectors such as rAAV7, rAAV8, rAAV9, and rAAVrh10. Through its license and collaboration with REGENX, Dimension has acquired preferred access to NAV vector technology and rights in REGENX product programs in multiple rare disease indications.
The number of Maryland companies receiving venture capital increased to 26 in the 3rd quarter of 2013, doubling the number of deals in the 2nd quarter. The 26 deals totaled $140 million, according to the latest PWCMoneytree report. Nationally venture capital investment activity rose 12% in terms of dollars and 5% in the number of deals compared to the second quarter of 2013. More than half of the deals were early and seed stage deals, signaling optimism among the report's sponsors regarding "the future of innovation and the vibrancy of the startup ecosystem."
For the ninth year Kevin Plank, Founder & CEO of Under Armour, will partner with the University of Maryland's Robert H. Smith School of Business to host one of the nation's toughest business competitions. There's $115K on the line, and how does access to Kevin Plank's professional network sound? Apply by January 6, 2014. Visit our web site to learn more about Plank's story and commitment to entrepreneurship. The elegibility, timeline, prize breakdown and more is listed below. Don't miss the chance to pitch your business to Plank and other top judges.
Application Deadline: January 6, 2014
Semifinal Round: February 21, 2014 @ Under Armour Headquarters, Baltimore, MD
Final Competition: April 4, 2014 @ Clarice Smith Performing Arts Center, University of Maryland
1776, the downtown startup hub that launched earlier this year with a grant from D.C. Mayor Vincent Gray's administration, has recruited Gray staffer David Zipper to head its for-profit venture arm.
Zipper was instrumental in mustering the mayor's support behind the initiative located at 1133 15th St. NW, which combines co-working, startup education, events and mentorship under one roof and brand. 1776 has so far received some $380,000 from the District, $200,000 of which went toward the initial 15,000 square foot build-out, with the rest funding the Challenge Cup global startup competition.
James Ramsey could easily move his business to where he lives in Eastern Virginia, but Maryland is just too rich in his opinion.
He would rather drive more than three hours each way every week to a house he rents in Baltimore to keep his business in Maryland. That's because with all the neighboring colleges in the state, he thinks the talent pool is too good to pass up.
The Life Sciences Discovery Fund (LSDF) has posted a revised 2012-2013 Granting Programs Request for Proposals (RFP) at http://www.lsdfa.org/documents/pdfs/LSDF_2012-2013_Granting_Programs_RFP.pdf that includes the following important changes:
Federal health care reform has been catching a bit of flack the last few weeks, as health insurance exchanges continue to experience severe technical difficulties.
But it’s not all bad. At a panel Thursday on health care information technology, Carolyn Quattrocki, who leads the governor’s Office of Health Care Reform, said that companies with bright ideas about how to use technology to improve health care policies are “so critical — and becoming more critical.”
Between federal health reform, a cache of federal agency headquarters and notable health care brands like Johns Hopkins, Maryland is a prime spot for up-and-coming health IT companies. But despite a wealth of resources, M. Jason Brooke had to look hard to find the help he and his business partner needed to launch their medical device company.
To help pave a smoother path for others, Brooke and a team of other entrepreneurs have organized Maryland HealthTech Coalition. The group is designed to bring together health IT companies to share ideas, contacts and resources.
A new report released today by The Science Coalition illustrates one of the many returns on investment of federally funded scientific research: the creation of new companies. Sparking Economic Growth 2.0 highlights 100 companies that trace their roots to federally funded university research and their role in bringing transformational innovations to market, creating new jobs and contributing to economic growth. An accompanying online database provides free access to company profiles and allows users to sort companies by federal funding agency, university affiliation, type of innovation and other criteria.
