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Cartesian Therapeutics to Present Late Breaking Data from Phase 1 2a Trial of RNA CAR T cell Therapy in Patients with Generalized Myasthenia Gravis Cartesian

Cartesian Therapeutics to Present Late-Breaking Data from Phase 1/2a Trial of RNA CAR T-cell Therapy in Patients with Generalized Myasthenia Gravis – Cartesian

By News Archive

Cartesian Therapeutics to Present Late Breaking Data from Phase 1 2a Trial of RNA CAR T cell Therapy in Patients with Generalized Myasthenia Gravis CartesianGAITHERSBURG, Md., May 10, 2022  – Cartesian Therapeutics, a fully integrated clinical-stage biotechnology company pioneering RNA cell therapy in and beyond oncology, will present late-breaking interim data from its Phase 1/2a clinical trial of Descartes-08 in patients with generalized Myasthenia Gravis (MG) today at the 14th Myasthenia Gravis Foundation of America (MGFA) International Conference on Myasthenia and Related Disorders.  The conference is in Miami, May 10–12, 2022.

The oral presentation, “RNA CAR T-cell Therapy for Myasthenia Gravis,” will be delivered today, Tuesday, May 10 at 10:50 a.m. ET by principal investigator Volkan Granit, M.D., of the University of Miami. A poster, “Phase 1b/2a Study of Autologous mRNA-Engineered Anti- B-cell Maturation Antigen Chimeric Antigen Receptor T-cells for Treatment of Severe Generalized Myasthenia Gravis,” will be presented at the conference today and tomorrow.

 

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Virginia’s Pocket Life Science Ecosystems are Booming · BioBuzz

By News Archive

VirginiaThere is no doubt that Virginia is open for business to the life sciences industry. Over the past several years, the state has seen significant growth in pocket ecosystems across the land, particularly in areas like Charlottesville, Richmond, and Blacksburg.

Some of the growth has been fueled by an infusion of federal monies related to the government’s efforts to mitigate the COVID-19 pandemic, while other growth has been driven by old-fashioned scientific innovation. Across the Old Dominion state, companies are driving research and development of novel therapies and more as they all combine their forces to bolster the life sciences ecosystem.

 

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TCC The Labs at Belward Farm websize

Trammell Crow Company Announces Plans for a Life Sciences Campus in Maryland

By News Archive

TCC The Labs at Belward Farm websizeThe Labs at Belward, located at the Belward Campus of The Johns Hopkins University, will Initially Provide 757,000 SF of Trophy Lab and R&D Facilities and Community Serving Amenities

Trammell Crow Company (TCC), a global commercial real estate developer, today unveiled plans to develop The Labs at Belward, a world-class life science campus, in the Shady Grove area of Montgomery County, Md. The Labs at Belward, located at the Belward Campus of The Johns Hopkins University, will initially include 757,000 square feet of trophy lab and research and discovery space across three buildings. The project has the potential to grow to approximately 1.6 million square feet across seven buildings. Construction of the initial 757,000 square feet will begin June 2023 and is slated to be completed in early 2025.

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507th Edition, May 10th, 2022

By BHI Weekly Newsletter Archives





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May 10, 2022

FOUNDING MEMBER OF

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Special Edition BioTalk: Dave Saunders, CTO & Co-Founder of Galen Robotics

Dave Saunders, CTO & Co-Founder of Galen Robotics, joins Rich Bendis before their 5/6/2022 Open House in Baltimore. (RSVP to OPENHOUSE@GALENROBOTICS.COM to attend) Also, view a demo of their technology at https://bit.ly/GalenRobotics. Rich and Dave and I discuss Digital Surgery, Choosing Baltimore, and their Design Philosophy.

Listen now via Google https://bit.ly/3w7lIr7, Apple https://apple.co/3MQRj6S, Spotify https://spoti.fi/3MNYfBH, Amazon https://amzn.to/3s7PTgj, and TuneIn https://bit.ly/3823iQo.

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How can your BioHealth business benefit from a review by BHI industry experts? Please register for our next Entrepreneur-In-Residence (EIR) day on May 18th and find out. To sign-up for any of the EIR dates in 2022, please follow this link.

These free 1:1 virtual sessions are an opportunity to discuss your company with experts in diagnostics, therapeutics, digital health and medical devices. If you’re a growth-stage biohealth company looking for unbiased advice on your pitch deck, commercialization strategy, evidence development or entrepreneurial challenges, our EIRs can help.

To sign-up for any of the EIR dates in 2022, please follow this link.

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University of Maryland Launches New Center to Bring Health Care's Vision of Tomorrow Into Focus

COLLEGE PARK, Md. (PRWEB) May 05, 2022

Ultrasound data displayed directly on a patient via augmented reality headsets. Immersive "grand rounds" for medical students and faculty even when they're in different locations. Virtual reality landscapes matched with classical opera to transport people with painful injuries outside of themselves, reducing the need for potentially addictive opioids.

These medical examples of extended reality (XR)–the umbrella term used for technology based in virtual and augmented reality or other immersive media–are already being prototyped or tested in clinical trials. But its widespread use in hospitals and other health care settings is currently hampered by technical challenges and sparse regulatory guidelines.

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Virginia Based AMPEL BioSolutions' Machine Learning Breakthrough Predicts Drug Options for Inflammatory Skin Diseases

CHARLOTTESVILLE, Va., May 3, 2022 — AMPEL BioSolutions today announces a breakthrough in precision and personalized medicine that could revolutionize the way doctors treat inflammatory skin diseases, such as Lupus, Psoriasis, Atopic Dermatitis and Scleroderma. Revealed in the peer-reviewed journal Science Advances, the paper details AMPEL’s breakthrough machine learning approach to characterize disease activity from gene expression data obtained from patient skin biopsies. The lab test, only a concept for the last few years, is now ready for development for practical use. AMPEL's initial focus was Lupus, but the test can be used for many autoimmune or inflammatory skin diseases that affect more than 35 million Americans.

AMPEL's innovative machine learning approach, which is now ready to be developed as a decision support biomarker test, could greatly impact health care by allowing physicians to identify the cause of patient disease symptoms and select appropriate treatment more precisely.  AMPEL’s approach is sufficiently sensitive to detect changes in clinically uninvolved skin so that early intervention may prevent systemic flares and skin damage apparent in lesions.  The application of AMPEL’s machine learning approach could also assist pharmaceutical companies in drug development and clinical trials.

Patients with chronic skin diseases often suffer from unpredictable disease activity that impacts daily activities like work and family life. Since unpredictable symptoms often result in trips to the Emergency Room, the ability to predict worsening disease and systemic involvement with routine skin biopsies has important health care and health economics implications. 

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Scheer Partners to Deliver More Spec-suites and Build-to-Suit Space in Maryland · BioBuzz

It’s been a big few years in the Biohealth Capital Region, especially big for commercial real estate firm Scheer Partners. After the success of buildings like 704 Quince Orchard, a 77,000-square-foot office building converted to lab space, Scheer Partners has continued to bring new buildings to market with both spec suites and build-to-suit space available for tenants of all sizes.

“Speed to market has been the tagline for the last year or so,” said Aaron Gambini, Assistant Vice President at Scheer Partners. “So it’s sort of creating move-in ready options for the market. It seems to be the way to go to start getting activity. And it’s really the next building that delivers that is the next building to lease.”

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506th Edition, May 3rd, 2022

By BHI Weekly Newsletter Archives





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May 3, 2022

FOUNDING MEMBER OF

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Maryland Commerce Secretary Mike Gill Guests on BioTalk with Rich Bendis Podcast

Mike Gill, Maryland Commerce Secretary, visits BioTalk to discuss Life Sciences in the State, growing the economy, and how we can continue building on our successes.

#Apple https://apple.co/3y8gVbA, #Google https://bit.ly/3vWZo3g, #Spotify https://spoti.fi/3w4uoP0, #Amazon https://amzn.to/3kz1uBc, #TuneIn https://bit.ly/3kxWZa0, or #YouTube https://bit.ly/39pFfLv.

Secretary Mike Gill is a business leader with four decades of experience as an entrepreneur, technology executive, investment banker, and public servant. He was tapped by Governor Larry Hogan in 2014 to lead the Maryland Department of Commerce as its first-ever Secretary and was asked by the Governor to again lead the Department in December 2021.

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Vita Therapeutics relocates to University of Maryland Biopark

From its new headquarters and lab space, the biotech company aims to generate state-of-the-art cellular therapeutics for the treatment of debilitating neuromuscular diseases and cancers

BALTIMORE, May 2, 2022 /PRNewswire/ — The University of Maryland (UM) BioPark announced today that Vita Therapeutics, a cell engineering company harnessing the power of genetics to develop cellular therapies to treat muscular dystrophies and solid tumors, has established offices and laboratory space within approximately 10,000 square feet of leased space in the BioPark. Vita Therapeutics will leverage the new space to bring together its 25+-person team under one roof for the first time with the goal of progressing its co-lead programs, VTA-100 and VTA-300. The company uses induced pluripotent stem cell (iPSC) technology to engineer specific cell types designed to replace those that are defective in patients.

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Rockville's Supernus Announces FDA Approval of Qelbree® for the Treatment of ADHD in Adults
  • First novel, nonstimulant option for adults with ADHD in 20 years
  • ADHD affects an estimated 10 million adults in the U.S.

ROCKVILLE, Md., April 29, 2022 (GLOBE NEWSWIRE) — Supernus Pharmaceuticals, Inc. (Nasdaq: SUPN), a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases, announced today that the U.S. Food and Drug Administration (FDA) approved an expanded indication for Qelbree (viloxazine extended-release capsules) for the treatment of attention deficit hyperactivity disorder (ADHD) in adult patients aged 18 and older. The FDA has now approved Qelbree for the treatment of ADHD in children (starting at age 6), adolescents and adults.

Approximately 16 million children, adolescents, and adults have ADHD in the U.S. While many children with ADHD outgrow it, up to 90% of those diagnosed with ADHD in childhood continue to have ADHD as adults.

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Kite’s Maryland CAR T-cell therapy site gets FDA go-ahead

Kite, a Gilead company, says the US Food and Drug Administration (FDA) has approved commercial production at the company's new CAR T-cell therapy manufacturing facility in Frederick, Maryland.

Image: https://www.biopharma-reporter.com

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How can your BioHealth business benefit from a review by BHI industry experts? Please register for our next Entrepreneur-In-Residence (EIR) day on May 18th and find out. To sign-up for any of the EIR dates in 2022, please follow this link.

These free 1:1 virtual sessions are an opportunity to discuss your company with experts in diagnostics, therapeutics, digital health and medical devices. If you’re a growth-stage biohealth company looking for unbiased advice on your pitch deck, commercialization strategy, evidence development or entrepreneurial challenges, our EIRs can help.

To sign-up for any of the EIR dates in 2022, please follow this link.

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6 life sciences leaders see Montgomery County as partner in success – Washington Business Journal

Home to nearly 18 federal agency headquarters, 36 federal labs, and more than 300 life science companies, it’s no surprise Maryland’s Montgomery County is a leader in the life sciences industry.

The six life sciences companies highlighted here consider Montgomery County critical to their success.

MaxCyte, Inc.

“The Montgomery County community has an expansive amount of experience and a perpetual abundance of innovative ideas based on excellent science,” says Doug Doerfler, CEO of MaxCyte, Inc. MaxCyte provides technologies to advance innovative cell-based research and next-generation cell therapeutics. The company’s Flow Electroporation® platform facilitates complex engineering of a wide variety of cells, currently focusing on immuno-oncology and gene editing.

Image: https://www.bizjournals.com

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Emmes and Casimir Announce Research About a Novel, Home-Based Assessment for Duchenne Muscular Dystrophy | Emmes

Emmes, a global, full-service Clinical Research Organization (CRO) dedicated to supporting the advancement of public health and biopharmaceutical innovation, today announced that Casimir’s research on the development of the Duchenne Video Assessment (DVA) scorecards was published in PLOS ONE.  Emmes acquired Casimir in March 2022, and the group is now part of Emmes’ Rare Disease Center, Orphan Reach™.

The DVA is a novel, home-based clinical outcome assessment that measures ease of movement among those with Duchenne muscular dystrophy (DMD) through identification of compensatory movement patterns.  Caregivers video record patients performing specific movement tasks at home using a secure mobile application.  The paper describes the development of the scorecards that DVA-trained physical therapists use to score the videos.

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Medcura Expands its Senior Leadership Team and Appoints Leading Neurosurgeon Dr. Kenneth Renkens as Chief Medical Officer

RIVERDALE, Md., April 26, 2022 /PRNewswire/ — Medcura, Inc., a commercial-stage medical device company, today announced the expansion of its senior management team to include Dr. Kenneth Renkens as its Chief Medical Officer. Dr. Renkens is a thought-leading neurosurgeon who co-founded the Indiana Spine Group and has been involved in the development and commercial success of numerous innovative products now widely used in operating rooms around the world.

Chosen for his deep expertise in neurosurgery and past involvement with numerous implantable surgical innovations, Dr. Renkens joins an experienced team with a demonstrated track record of execution in delivering groundbreaking hemostat innovations. The Medcura team is now narrowly focusing its attention on bringing more disruptive technology to the Operating Room (OR).

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Washington D.C. Mayor Bowser Announces $92 Million Initiative to Catalyze Health Innovation and Address Disparities

Thursday, April 28, 2022

The HOPE Initiative will utilize federal funds to create new lab space, technology advancement & new services

(Washington, DC) Today, Mayor Muriel Bowser and the Office of the Deputy Mayor for Planning and Economic Development (DMPED), announced the Helping Our People Endure (HOPE) initiative, which intends to invest $92 million in the life sciences, to catalyze health innovation and address disparities in the District of Columbia. The participants will be part of the District of Columbia's application to the U.S. Department of Treasury's Capital Project Fund.

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Virginia Based AMPEL BioSolutions' Machine Learning Breakthrough Predicts Drug Options for Inflammatory Skin Diseases

CHARLOTTESVILLE, Va., May 3, 2022 — AMPEL BioSolutions today announces a breakthrough in precision and personalized medicine that could revolutionize the way doctors treat inflammatory skin diseases, such as Lupus, Psoriasis, Atopic Dermatitis and Scleroderma. Revealed in the peer-reviewed journal Science Advances, the paper details AMPEL’s breakthrough machine learning approach to characterize disease activity from gene expression data obtained from patient skin biopsies. The lab test, only a concept for the last few years, is now ready for development for practical use. AMPEL's initial focus was Lupus, but the test can be used for many autoimmune or inflammatory skin diseases that affect more than 35 million Americans.

AMPEL's innovative machine learning approach, which is now ready to be developed as a decision support biomarker test, could greatly impact health care by allowing physicians to identify the cause of patient disease symptoms and select appropriate treatment more precisely.  AMPEL’s approach is sufficiently sensitive to detect changes in clinically uninvolved skin so that early intervention may prevent systemic flares and skin damage apparent in lesions.  The application of AMPEL’s machine learning approach could also assist pharmaceutical companies in drug development and clinical trials.

Patients with chronic skin diseases often suffer from unpredictable disease activity that impacts daily activities like work and family life. Since unpredictable symptoms often result in trips to the Emergency Room, the ability to predict worsening disease and systemic involvement with routine skin biopsies has important health care and health economics implications. 

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Life sciences partnerships key to fast-track products in Montgomery County, Maryland – Washington Business Journal

Biotechnology innovation is a team sport.

While we often credit the discovery of a promising new therapy to a single scientist or research team, turning that discovery into a viable product patients can access requires a vast network of players. There are manufacturing platforms capable of producing new cell and gene therapies, teams to support preclinical and clinical trials, real estate developers that offer cutting-edge laboratory space and experts across a wide range of fields who all contribute to bringing a product to market.

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How is Montgomery County built for bio? Get the answers from these life sciences execs (video) – Washington Business Journal

Montgomery County is well known for many transformative firsts in life sciences. First to sequence the human genome; first gene therapy for sickle cell, first cell therapy for COVID-19 — and that’s just the start.* Montgomery County is an epicenter for translating knowledge into life-changing treatment and cures, with gene and cell therapies representing some of the most promising advancements in human health.

Image: Being part of the industry that delivers building solutions to help scientists do their work is what drives Pat Larrabee, CEO of Facility Logix. – https://www.bizjournals.com

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Bringing biotech to market faster in Montgomery County, Maryland – Washington Business Journal

In biotechnology, speed matters.

Emerging technology has opened a new world of possibilities for treating — and potentially curing — diseases. Scientists are developing cell and gene therapies designed to help patients with cancer, heart disease, liver disease, Parkinson’s disease, Alzheimer’s and many other conditions. The faster they can get these therapies from the laboratory through clinical trials and into production, the sooner people will be able to benefit.

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Life Sciences | Virginia Economic Development Partnership

Top companies in the life sciences industry choose to locate in Virginia – and flourish here – because of the state’s top talent, advanced culture of innovation, outstanding logistical advantages, competitive costs, and top-ranked business climate. Virginia’s life sciences sector has gained significant momentum in recent years, with 20 life sciences industry projects announced in just the past three years, representing over 1,400 jobs and $1.2 billion in investment. Recent announcements include U.S. Pharmacopeia, AMPAC, Civica, Merck, GlaxoSmithKline (GSK), Bausch + Lomb, and Virginia-grown biotech firm Grenova.

Image: https://www.linkedin.com/

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The ARPA-H (Health) Headquarters: Where Will It Be, and Should I Care?

The medical science publication Stat just published an article about Congressional interest in the location of ARPA-H headquarters, the new $6 billion effort to fund high, risk-high reward health research and cures. We are about to witness a biotech version of the Amazon HQ2 competition, with states and jurisdictions across the country angling to land this headquarters facility.

It is great to see the national interest in housing ARPA-Headquarters, but this project should not distract jurisdictions from planning for the far more important and
numerous other opportunities emerging as Congress and the White House put the finishing touches on current and new programs and projects to fund applied science and health research programs. Both the science community and commercial real estate (CRE) industry should take notice.

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505th Edition, April 26, 2022

By BHI Weekly Newsletter Archives





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April 26, 2022

FOUNDING MEMBER OF

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Raymond Blanchard, Associate Director of IP & Licensing with QIAGEN, visits BioTalk

QIAGEN Associate Director of IP & Licensing, Raymond Blanchard, chats with Rich Bendis on BioTalk to discuss innovation, intellectual property and having a large footprint in the BioHealth Capital Region.=

Listen now via #applepodcast https://apple.co/38nyPw4, #googlepodcast https://bit.ly/37Bb83q, #spotifypodcasts https://spoti.fi/3Mx7Ahp, #amazonpodcast https://amzn.to/3OzKN6j, #TuneIn https://bit.ly/3Mspodh, or #YouTube https://bit.ly/38mJB5t. #podcast

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MIMETAS participates in €325 million Oncode-PACT initiative to accelerate and improve oncology drug development

LEIDEN, The Netherlands, April 14, 2022 – MIMETAS, a global leader in organ-on-chip-based disease models, is a partner in the Oncode-PACT initiative that has been granted today an amount of €325 million by the Dutch National Growth Fund.

Oncode Institute will lead the Oncode-PACT consortium and its operations. With this investment, the consortium will develop cancer drug candidates faster and bring them to patients sooner. As a partner in Oncode-PACT, MIMETAS will develop the next generation of patient-specific cancer organoid models that include immune cells, blood vessels, and other essential cell types to drive novel cancer drug discovery and developm ent. Using these models, MIMETAS will screen compounds and targets using fully integrated, automatic phenotypic screening lines with AI data interpretation, bringing early validation and de-risking to the cancer drug development pipeline.

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Aurinia Announces Year-Two Commitment to Patient Navigation Grant Program to Address Barriers for Individuals Living with Lupus and Lupus Nephritis

Life Sciences Business Strategist

– Company seeks proposals to create and sustain community-focused programs to support underserved populations with these conditions –  

VICTORIA, British Columbia & ROCKVILLE, Md.–(BUSINESS WIRE)–Aurinia Pharmaceuticals Inc. (NASDAQ: AUPH) (Aurinia or the Company) today, affirmed its commitment to individuals living with the systemic lupus erythematosus (SLE) and lupus nephritis (LN) through the sponsorship of charitable grants to establish or expand community-focused patient navigator programs. This is the second year of this unique program aimed at eliminating barriers to care for individuals living with SLE/LN. LN is a serious manifestation of SLE that can cause irreversible kidney damage and kidney failure and significantly affects more Black, Asian, and Hispanic individuals than non-Hispanic White individuals. Selected applicants may receive up to $50,000 over a one-year period.   

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Kite Receives U.S. FDA Approval of New State-of-the-Art CAR T-Cell Therapy Manufacturing Facility in Maryland

April 19, 2022 12:00 UTC   — Kite’s Global CAR T-Cell Therapy Manufacturing Network Increasing Capacity by 50% to Meet Patient Demand for New Cancer Therapies — Scalable and Adaptable Facility Provides Flexibility for Current and Future Cell Therapy Innovation   SANTA MONICA, Calif.–(BUSINESS WIRE)– Kite Pharma, a Gilead Company (Nasdaq: GILD), today announced the U.S. Food and Drug Administration (FDA) has approved commercial production at the company's new CAR T-cell therapy manufacturing facility in Frederick, Maryland. The site will produce Kite’s FDA approved CAR T-cell therapy used to treat blood cancer.  

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Maryland Life Science Advisory Board Welcomes New Members · BioBuzz

The Life Sciences Advisory Board added three new members, Ellington West of Sonavi Labs, Michael Weingarten of the National Cancer Institute, and GlaxoSmithKline’s KaShauna G. Rohlehr.

Ellington West West was tapped to serve as chief executive officer of Sonavi Labs in 2018. Along with Ian McLane, she is the co-founder of the Johns Hopkins startup digital stethoscope technology company. West was the founder of West Labs Research Group at Johns Hopkins where the company’s core Feelix technology was developed.

Image: https://biobuzz.io

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500,000-square-foot life science campus coming to Jefferson Technology Park in Frederick County

Apr. 22—Construction will start this September on a 500,000-square-foot life science campus in Frederick County's Jefferson Technology Park that the developer says will be a $140 million investment in the community.

The Labs at Jefferson Park will include about 200,000-square-feet of research and development lab space, said Eric Fischer, a managing director with Trammell Crow Co., the project's developer. It is slated to be finished next year.

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Initial Results from Novavax' COVID-19-Influenza Vaccine Trial are First to Show Feasibility of Combination Vaccine
  • Phase 1/2 clinical trial of COVID-19-Influenza combination vaccine candidate indicates vaccine is well-tolerated and immunogenic
  • Data from this combination trial will inform planned Phase 2 dose confirmation trial, scheduled to begin by the end of 2022
  • Immune response confirmed in stand-alone influenza vaccine and combination vaccine with potential path forward for both

GAITHERSBURG, Md., April 21, 2022 /PRNewswire/ — Novavax, Inc. (Nasdaq: NVAX), a biotechnology company dedicated to developing and commercializing next-generation vaccines for serious infectious diseases, today announced initial results from the Phase 1/2 clinical trial of its COVID-Influenza Combination Vaccine (CIC). The CIC combines Novavax' COVID-19 vaccine, NVX-CoV2373, and its quadrivalent influenza vaccine candidate. The CIC trial demonstrated that formulating the combination vaccine is feasible, well-tolerated and immunogenic.

"We continue to evaluate the dynamic public health landscape and believe there may be a need for recurrent boosters to fight both COVID-19 and seasonal influenza," said Gregory M. Glenn, M.D., President of Research and Development, Novavax. "We're encouraged by these data and the potential path forward for a combination COVID-19-influenza vaccine as well as stand-alone vaccines for influenza and COVID-19."

The safety and tolerability profile of the combination vaccine was consistent with the stand-alone NVX-CoV2373 and quadrivalent nanoparticle influenza vaccine reference formulations in the trial. The combination vaccine was found to be generally well tolerated. Serious adverse were rare and none were assessed as being related to the vaccine.

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The ARPA-H (Health) Headquarters: Where Will It Be, and Should I Care?

The medical science publication Stat just published an article about Congressional interest in the location of ARPA-H headquarters, the new $6 billion effort to fund high, risk-high reward health research and cures. We are about to witness a biotech version of the Amazon HQ2 competition, with states and jurisdictions across the country angling to land this headquarters facility.

It is great to see the national interest in housing ARPA-Headquarters, but this project should not distract jurisdictions from planning for the far more important and
numerous other opportunities emerging as Congress and the White House put the finishing touches on current and new programs and projects to fund applied science and health research programs. Both the science community and commercial real estate (CRE) industry should take notice.

Read More

Biden’s Biotech Moonshot Has The Money. Now Cities Want It In Their Backyard

Cities and states jockeying for position in the race for biotech dollars and talent have their sights set on a whale that comes along once in a generation.

When President Joe Biden announced last year that the federal government is launching a new outfit, the Advanced Research Projects Agency for Health, dedicated to funding moonshot tech research, he kicked off a new, high-stakes battle among municipalities that are eager to land the headquarters of a federal agency dedicated to advancing and funding cutting-edge research.

Image: Creative Commons The new ARPA-H, an agency designed to fund moonshot health research, will fall under the umbrella of the National Institutes of Health.

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AURP Announces Executive Team Realignment – Digital Journal

TUSCON, AZ / ACCESSWIRE / April 5, 2022 / AURP, the leading nonprofit representing research parks, innovation districts and regional technology clusters, today announced a realignment of its executive team to optimize AURP’s continued success and global development strategies.

Vickie Palmer, current Director of Operations, has been appointed AURP CEO. Palmer assumes this executive leadership role following her 15 years of experience significantly expanding AURP’s membership and sponsorship community, plus overseeing AURP’s roster of events and programs. During her time with AURP, Palmer has led the organization’s membership, event management and overall operations while working closely with the organization’s CEO, Board of Directors and membership community.

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Don't Miss Out! Pitching To Get Attention Workshop

Join ETC and Squadra Ventures on May 18, 2022 from 5:00 pm – 7:00 pm at Monument City Brewing for the second Open Mic Pitch Night!  This is an opportunity for the Baltimore community to embrace new technology and foster connections. This is where entrepreneurs can practice pitching their startup or idea to an audience and receive feedback from a group of like-minded peers, investors, and tech leaders in a safe space.

Pitches will be casual – no presentations – simply get up on stage and spend 2 minutes telling the audience about your company or idea. During the networking hour, audience members will have the opportunity to ask companies questions.

To apply to pitch; please fill out this form by Tuesday, May 17th, 2022 at 11:59 PM. After completing the form you will receive an email with instructions on what to expect, your pitch timeslot, and any other information you may need. If you have any questions, please contact Breonna Massey at bmassey@etcbaltimore.com.

Happy hour drinks and light appetizers will be provided.

Click here to register.

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Join BLUE KNIGHT™ this June: Accelerating preparedness together

Did you hear? Our second BLUE KNIGHT™ Symposium will take place June 9, 2022, and we’re excited to present your first chance to register! Tune in virtually from wherever you are around the world for a day of live programming. This year’s theme, The Power of Partnering to Accelerate Preparedness, aims to answer the questions startups have around accelerating innovations and earning a seat at the global preparedness table.

We echo that theme in today’s exclusive Q&A with Dr. David Boucher of ASPR and Dr. Karen Martins of BARDA, on the power of collaboration to build global resiliency toward health security threats. These experts share advice for early-stage companies and explore their experiences partnering to move "faster and better". Read more here.

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504th Edition, April 19, 2022

By BHI Weekly Newsletter Archives





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April 19, 2022

FOUNDING MEMBER OF

2022 Happy New Year Image

Governor Hogan Announces Maryland Cancer Moonshot Initiative; $216 Million in Initial Investments in Comprehensive Cancer Centers, Cutting-Edge Research of Treatments and Cures · BioBuzz

ANNAPOLIS, MD—Governor Larry Hogan today announced a new Maryland Cancer Moonshot Initiative to expand and accelerate cancer detection, screening, prevention, treatment, and research in the state. The state is committing $216 million in investments as a down payment to jumpstart this far-reaching initiative to save lives, including the first ever comprehensive cancer center in Prince George’s County.

Image: https://governor.maryland.gov/

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Ellume manufacturing rapid at-home COVID-19 test kits in Maryland

FREDERICK, Md. — The first company to make rapid take-home COVID-19 tests is now making them in Maryland.

A few months ago, it was nearly impossible to find an at-home COVID-19 test in stores across Maryland. Now, store shelves are stocked with boxes of test kits from different brands.

But it's not just about COVID-19 at Ellume's manufacturing plant In Frederick. The large manufacturing facility was built to support the federal government's response to the current pandemic and future ones.

Hailed as a medical breakthrough a year ago, Ellume's COVID-19 at-home test kits are rolling off a state-of-the-art assembly line in Frederick, which held its grand opening Thursday.

Image: https://www-wbaltv-com.cdn.ampproject.org

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BHI has an immediate opening for a Life Sciences Business Strategist.

Life Sciences Business Strategist

BioHealth Innovation (BHI) is an innovation intermediary that facilitates the commercialization of emerging technologies in the BioHealth Capital Region (Maryland, DC and Virginia).  We are seeking a Life Sciences Business Strategist to join our team remotely.

The right candidate will be an energetic and continuous learner who is passionate about accelerating the adoption of new technologies to improve lives. The position is geared toward an early-career scientist (generally in their first 5-7 years after receiving their PhD) who wants to engage with the biohealth industry in new ways.  

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NasaClip Receives a $256,000 Grant by the National Science Foundation | TEDCO

The NasaClip device provides simple and effective nosebleed rescue at home or anywhere, using hands-free, external nasal compression with intranasal sponges that medicine can be added to – helping to stop nosebleeds fast.

Image: https://www.tedcomd.com

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Pre-Application Webinar: NIA Healthy Aging Start-Up Challenge and Bootcamp to Foster Diversity and Accelerate Innovation (April 22 – 2PM)

Individuals from diverse backgrounds can provide unique and valuable contributions in the research and development of life science innovations that prevent disease, prolong life, and promote health. However, certain groups, such as women and individuals from racial/ethnic minoritized groups, remain underrepresented in the U.S. biomedical sciences and in life science entrepreneurship.

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Major life sciences campus coming to Maryland | Maryland Business News

A new 500,000 square-foot life science campus is being planned for Frederick County.

With two 100,000 square-foot research and development labs; two additional 145,000 square-foot production buildings; co-working space; conference rooms; and more, The Labs at Jefferson Tech Park will provide in demand, state-of-the-art space for life science companies looking to locate along the I-270 corridor.

The campus – which aims to be the “premier biodiscovery campus” in the county – is also expected to host numerous fitness and walking trails, outdoor green space, a cafe, and plenty of parking.

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Introducing the Inaugural NIH 21st Century Scholars Program Cohort | SWD at NIH

Today, I am pleased to introduce the inaugural cohort of the NIH 21st Century Scholars Program—a new COSWD-sponsored initiative to promote awareness of the science of scientific workforce diversity. Six mentors and 13 cohort engagement participants from the NIH extramural scientific workforce were selected; together, they will build a vibrant, self-reinforcing culture of mentoring and support with a focus on diversity at the NIH.

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Webcast on Value Analysis at Children’s National | April 20 at 1:30p EST

Please join the inaugural webcast “Tell Me Something I Don’t Know,” hosted by Children’s National Hospital (CNH) Innovation Ventures and the National Capital Consortium for Pediatric Device Innovation (NCC-PDI). In this episode, we learn about the process of selecting novel technologies for implementation at CNH. Jennifer Yin, MSN, RN, CVAHP, hospital’s Value Analysis Clinical Program Manager, will engage in a fireside chat with Francesca Joseph, MD, FAAP, Pediatrician at CNH and co-Investigator of NCC-PDI. Jennifer and Francesca will provide a general understanding of the Value Analysis process and highlight topics most relevant to medical device innovators.

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Flu-COVID Combination Test the Next Target for Ellume as New BioHealth Capital Region Facility Opens

A Brisbane-based company that has targeted the premium end of the COVID home diagnosis boom has officially opened its 20,000-square-metre facility in the US, but its founder is now nervous about a potential flu pandemic as "vaccine weariness" sets in.

Ellume founder and CEO Sean Parsons tells Business News Australia the opening of the facility in Frederick, Maryland moves "moves us into pretty rarefied air" of companies that have massive capability for manufacturing tests for COVID and other viruses, at around 500,000 per day.

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California Life Sciences – Sector Report 2021

One of the most impactful moments I’ve witnessed working in the life sciences sector happened on the campus of Edwards Lifesciences last year.

Just months after having surgery, a patient met face to face with the team behind her heart valve replacement. She got to thank the people who built and inspected the very device now helping her heart function properly. They hugged, they clapped. For many of the Edwards team, it was the first time they were able to meet a patient whose life they changed.

It’s not often we see these moments up close – the ones where it’s so clear why we do what we do in the life sciences. This is what we do—deliver innovative solutions for healthier lives.

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The Top European Biotech Investments in February 2022

Companies developing lab automation, ophthalmological treatments, and novel foods received Europe’s top biotech investments in February 2022.

European and Israeli biotech investments in February 2022 narrowly beat January’s performance. Life sciences companies in these regions bagged 52 private investments and initial public offerings (IPOs), worth €664M in total. Meanwhile, January’s tally was 41 deals totaling €660M. Neither month matched the biotech investment highs of December 2021.

Image: https://www.labiotech.eu

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503rd Edition, April 12, 2022

By BHI Weekly Newsletter Archives





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April 12, 2022

FOUNDING MEMBER OF

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BHI has an immediate opening for a Life Sciences Business Strategist.

Life Sciences Business Strategist

BioHealth Innovation (BHI) is an innovation intermediary that facilitates the commercialization of emerging technologies in the BioHealth Capital Region (Maryland, DC and Virginia).  We are seeking a Life Sciences Business Strategist to join our team remotely.

The right candidate will be an energetic and continuous learner who is passionate about accelerating the adoption of new technologies to improve lives. The position is geared toward an early-career scientist (generally in their first 5-7 years after receiving their PhD) who wants to engage with the biohealth industry in new ways.  

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How can your BioHealth business benefit from a review by BHI industry experts? Please register for our next Entrepreneur-In-Residence (EIR) day on April 20th and find out. (Only 3 spots left!)

These free 1:1 virtual sessions are an opportunity to discuss your company with experts in diagnostics, therapeutics, digital health and medical devices. If you’re a growth-stage biohealth company looking for unbiased advice on your pitch deck, commercialization strategy, evidence development or entrepreneurial challenges, our EIRs can help.

To sign-up for any of the EIR dates in 2022, please follow this link.

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BiOneCure Therapeutics Announces FDA Clearance of Investigational New Drug (IND) Application for BIO-106, a Novel TROP2 ADC for the Treatment of Advanced Solid Tumors · BioBuzz

GERMANTOWN, Md., April 6, 2022 /PRNewswire/ — BiOneCure Therapeutics, Inc. announced that the U.S. Food and Drug Administration (FDA) has cleared the IND for BIO-106, an antibody-drug conjugate (ADC) designed to target TROP-2 to treat a broad range of advanced solid tumors.

 The clinical study cleared by the FDA, known as StarBridge-1, is a Phase I/II, multicenter, open-label study to evaluate the safety, pharmacokinetics and preliminary anti-tumor activity of BIO-106 as monotherapy and in combination with pembrolizumab in patients with advanced cancers.

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Rockville Economic Development Inc. (REDI) enters strategic partnership with Federal Laboratory Consortium (FLC) – Rockville Economic Development, Inc

WASHINGTON, DC and ROCKVILLE, Md., March 28, 2022 – The Federal Laboratory Consortium (FLC) has entered into a strategic partnership with Rockville Economic Development, Inc. (REDI), based in Rockville, MD as part of an ongoing campaign to help local businesses and entrepreneurs with innovative technologies succeed through collaborations with federal laboratories.

The Rockville Economic Development, Inc. (REDI) was formed in 1997 as a public-private partnership (formerly known as the Greater Rockville Partnership) by the City of Rockville, Maryland, to build the city’s economic base through entrepreneurship, expansion, retention, and recruitment programs. REDI and the FLC signed a Memorandum of Understanding on March 22, 2022.

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Senate Confirms Laurie Locascio to Lead Tech Standards Agency – Nextgov

The U.S. Senate confirmed Laurie Locascio, a former bioengineering professor at the University of Maryland, to helm the National Institute of Standards and Technology on Thursday.

Following Locascio’s nomination by President Joe Biden back in 2021, the Senate voted in her favor during an April 8 voice vote. Her nomination was first approved by the Senate Committee on Commerce, Science and Transportation before being sent to the floor for a final vote.

Image: J. STOUGHTON/NIST

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What's around the bend for the Maryland tech economy? These local leaders shared some thoughts – Technical.ly

The impacts of various ongoing developments, from the metaverse’s increasing prominence to the forthcoming gubernatorial shift, on Maryland’s tech economy were on the minds of attendees and panelists alike at last Thursday’s Digital Transformation Summit.

The Maryland Tech Council hosted its third iteration of the annual convention, in which the economic development group looks at the Maryland tech economy’s future, at the Maryland Jockey Club in Laurel.

Image: (L to R) Fearless' design director Jordan Watts; Exelon's principal product designer Chris-Anne Correa; Mindgrub's research and experience design director Shannon Hosmer; Christine Jackson, director of digital Strategy for the National Aquarium; and Solomon Scott, engineering lead, for The Washington Post, speak on a panel during the third annual Digital Transformation Summit. – https://technical.ly

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What It Means for a Pandemic Like Covid to Become 'Endemic’ – The New York Times

For months, some American and European leaders have foretold that the coronavirus pandemic would soon become endemic. Covid-19 would resolve into a disease that we learn to live with. According to several governors, it nearly has.

But we are still in the acute phase of the pandemic, and what endemic Covid might look like remains a mystery. Endemic diseases can take many forms, and we do not know yet where this two-year-old disease will fall among them.

Image: https://www.nytimes.com

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The 'Top 25 Innovators' in health care, according to Modern Healthcare

Modern Healthcare last week released its annual list of the "Top 25 Innovators," recognizing leaders who initiate and lead change in the health care industry.

Methodology For the list, Modern Healthcare accepted nominations from Nov. 22, 2021 to Jan. 31, 2022.

To be eligible, nominees had to be at the director level or higher within a provider organization—including a hospital, health system, clinic, or physician group—or an insurer. 

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Brian Coblitz Appointed Executive Director of GW Technology Commercialization Office | GW Today | The George Washington University

CONSHOHOCKEN, Pa.–(BUSINESS WIRE)–AmerisourceBergen, a global healthcare solutions company, today announced the establishment of AB Health Ventures, a dedicated corporate venture capital fund that will invest in and partner with emerging healthcare startup companies working to transform healthcare for people and animals globally. AB Health Ventures will build on AmerisourceBergen’s ongoing commitment to delivering innovation for its customers.

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Home | About BHI | BHI News | Programs | Partners | Contact

Copyright AA(C) BioHealth Innovation 2021
All Rights Reserved.


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How can your BioHealth business benefit from a review by BHI industry experts? Please register for our next Entrepreneur-In-Residence (EIR) day on May 18th and find out. To sign-up for any of the EIR dates in 2022, please follow this link.

By News Archive

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These free 1:1 virtual sessions are an opportunity to discuss your company with experts in diagnostics, therapeutics, digital health and medical devices. If you’re a growth-stage biohealth company looking for unbiased advice on your pitch deck, commercialization strategy, evidence development or entrepreneurial challenges, our EIRs can help.

 

To sign-up for any of the EIR dates in 2022, please follow this link.

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