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EntreMed (Nasdaq: EMND) has been through plenty of turbulence. In 1998, it was the subject of a breathless front page New York Times story suggesting the biotech was on the verge of curing cancer, based on promising mice studies. Those hopes (and EntreMed’s share price) deflated in the coming years, when the company found itself shedding jobs and executives and struggling to survive.

But through it all, EntreMed remained EntreMed. No longer: the Rockville company’s shareholders have voted to change its name to CASI Pharmaceuticals, as of June 16. The company will now trade under the ticker symbol CASI.

kloudtrack®, a leader in cybersecurity and cloud computing (cyber|cloud) technologies and solution services for sensitive data, process management and Governance, Risk and Compliance (GRC), will team up with the University of Maryland’sRobert H. Smith School of Business and Cisco Systems (NASDAQ:CSCO) to establish the first Innovation Sandbox™ exchange catering to the innovation, workforce development and technology roadmapping needs of public and private sector healthcare, and medical and life science (HealthTech) organizations.   

The project was announced as part of today’s Maryland Economic Development Association Summer Conference at UMD, themed “Health Innovations: Impact on Economic and Workforce Development.”

After all the angst generated by the Affordable Care Act, and all the punditry, noise, and debate that accompanied its rollout, you might conclude that there are no practical solutions to our healthcare challenges.  But, of course, there are new answers and solutions and new, creative approaches to solving healthcare problems. You just have to look at innovative, private sector enterprises.  And if you do, you might find one of the more innovative answers to eldercare right there in your old-fashioned television set.  Just ask Kian Saneii, CEO of Independa.

But first, a little background.  One of the more troubling and difficult areas of healthcare is the growing needs of the elderly, including both preventive care and the management  of long-term, chronic illnesses.   This has been a well-understood fact for quite some time.  Saneii and the Independa team he began assembling in 2009 set out to find practical real-world solutions to these challenges.  How they did this is an instructive case study in innovation, pragmatism and common sense.

EY unveiled on Thursday evening its 2014 Entrepreneur of the Year Maryland winners in eight categories.

The honorees were announced in front of a packed crowd at a black-tie event at the Hilton Baltimore. The awards program recognizes high-growth entrepreneurs who demonstrate excellence and success in such areas as innovation, financial performance and personal commitment to their businesses and communities.

Maryland has retained top rankings in the U.S. Chamber of Commerce Foundation’s annual Enterprising States study released Wednesday.

For the third consecutive year, the State ranked No. 1 in Innovation and Entrepreneurship. For the second year in a row, Maryland ranked third in the nation for its Talent Pipeline.

Maryland is missing out on as many as 7,000 jobs and millions of dollars of investment as companies build data centers in neighboring Virginia, according to a report from Baltimore accounting firm Glass Jacobson.

Data centers provide cloud storage and are crucial to supporting the kinds of technology firms that have been opening in and relocating to Baltimore.

London-based Index Ventures has just announced a new $542 million fund for seed-stage companies that have raised under $20 million.

The firm says it will invest in European startups mainly, but may make a few bets on companies from Israel and the U.S.

I read an interesting Wall Street Journal article recently that discussed the war between tech companies to control future consumer distribution platforms. The article explains that the cash-flush giants “…each want to own the digital platform where people communicate, shop and seek entertainment.” This got me thinking about platforms in healthcare.

Right now, it’s fair to say that there are three major healthcare platforms. Insurance companies such as Aetna, WellPoint, United Healthcare and Humana have substantial members. However, mentioned in the article is the continual need for innovation. Tech behemoths are“…aware of all the big companies that died because they rested on their laurels.”

Novavax Inc. (Nasdaq: NVAX) said Wednesday it has raised $115 million in gross proceeds by selling 28.75 million shares of its common stock, which the Gaithersburg biotech plans to pour into its pipeline.

Some of the net proceeds will go toward advancing Novavax’s Respiratory Syncytial Virus (RSV) nanoparticle vaccine into a Phase 2 trial in elderly subjects this year. The biotech is also studying its RSV vaccine for pediatric and maternal populations.

The University of Maryland, along with the George Washington University and Virginia Tech, have added the Johns Hopkins University to the National Science Foundation’s  Innovation Corps (I-Corps ™) regional collaboration called DC I-Corps.  JHU becomes the newest member university of the National Science Foundation’s National Innovation Network.

The NSF has approved a request from the three original universities to officially include Johns Hopkins in the I-Corps program’s “node” in the Mid-Atlantic called DC I-Corps, which was formed last year with $3.75 million in NSF funding. It is one of five regional nodes established nationwide by the NSF, and the first to expand its membership. Together, these five nodes currently form the basis of the National Innovation Network, which links together select universities with established entrepreneurs and venture capitalists to train faculty and student researchers from throughout the U.S. to transform ideas into products and get them on the market.