Nextcure logo

BELTSVILLE, Md., Jan. 10, 2025 (GLOBE NEWSWIRE) -- NextCure, Inc. (Nasdaq: NXTC), a clinical-stage biopharmaceutical company committed to discovering and developing novel, first-in-class, and best-in-class therapies to treat cancer, today announced the first patient has been dosed in its Phase 1 study of LNCB74, a B7-H4-targeting antibody-drug conjugate (ADC) as a therapeutic for treating multiple cancers.

Veralox

FREDERICK, Md.Jan. 9, 2025 /PRNewswire/ -- Veralox Therapeutics, a clinical-stage biotechnology company developing a new class of therapies targeting the 12-lipoxygenase (12-LOX) pathway, announced today that it has entered into an exclusive agreement with Nudge Therapeutics to acquire the company and their preclinical cyclic AMP-GMP (cGAS) inhibitor compounds.  The agreement allows Veralox to continue development of Nudge's compounds and trigger acquisition of the company upon achievement of downstream milestones. Financial terms were not disclosed.

Qiagen

GERMANTOWN, Md., & VENLO, The Netherlands--()--QIAGEN (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced the U.S. regulatory clearance of the first in a series of QIAstat-Dx Gastrointestinal Panel tests for clinical use.

This clearance by the U.S. Food and Drug Administration (FDA) marks the second mini syndromic panel in the U.S. and made available for use with QIAstat-Dx systems, supporting QIAGEN's strategy to improve patient treatment options in this important market.

The 2025 clearance involves the QIAstat-Dx Gastrointestinal Panel 2 Mini B&V (bacterial and viral) covering five causes of gastrointestinal illness that are recommended by the Infectious Diseases Society of America (IDSA): the bacteria CampylobacterSalmonella, Shiga-like toxin E.Coli (STEC) and Shigella, along with Norovirus, one of the most common causes of gastrointestinal infection and an important target during the winter season.

Tompkins

Montgomery County, MD — The Montgomery County Economic Development Corporation (MCEDC) announced that Bill Tompkins will step down as President & CEO when his term ends in August 2025. Tompkins has served in this role since August 15, 2022.

“This marks a significant moment for MCEDC,” stated Elana Fine, Chair of the Board of Directors. “We extend our gratitude to Bill for his outstanding leadership over the past six years, as both the Chief Operating Officer and as President & CEO. His dedication has laid a strong foundation for future growth while fostering inclusion, driving collaboration, and ensuring stability during challenging times.”

DMV Innovation

The Washington D.C., Maryland, and Virginia (DMV) region has quickly become one of the nation’s top destinations for startups and tech innovation. With over 270,000 tech jobs and $5 billion in venture capital raised in 2023, the DMV stands out as a vibrant and rapidly growing ecosystem.

In a recent LinkedIn post, Christon Hill, Program Manager at Georgetown Tech Ventures (GTV) and the Office of Technology Commercialization (OTC) at Georgetown University, highlights the factors driving this growth. He points to the region’s proximity to federal agencies, cutting-edge research institutions, and a culture of collaboration as key ingredients for success.

Emergent

GAITHERSBURG, Md., Jan. 08, 2025 (GLOBE NEWSWIRE) -- Emergent BioSolutions Inc. (NYSE: EBS) today announced the exercise of contract option and modification valued at approximately $20 million to supply BioThrax® (Anthrax Vaccine Adsorbed) to the U.S. Department of Defense (DoD). The first delivery, which was valued at approximately $7 million began in December 2024, and remaining deliveries are expected in 2025.

ESSEX Part of Emmes Group Logo

ROCKVILLE, Md.Jan. 7, 2025 /PRNewswire/ -- Essex Management, an Emmes Group company and a leader in biomedical informatics and health information technology, is pleased to announce the appointment of David Loose as Chief Executive Officer (CEO), effective immediately. David succeeds Kevin Hurley, who has served as CEO since February 2019 and will transition to the role of Executive Advisor.

David Loose joined Essex Management as a partner in February 2009 and has played a pivotal role in the company's growth. Starting as Vice President for Business Operations and Development, he later served as Chief Business Officer, overseeing critical operations, driving client-focused innovation, and delivering strategic initiatives such as NCI's Clinical Trials Reporting Program (CTRP). His leadership and dedication to Essex's mission have been instrumental in building its reputation as a trusted partner in the biomedical and health technology sectors.

"David's leadership and dedication to Essex's mission make him the ideal choice to guide the company forward," said Sastry Chilukuri, CEO of Emmes Group. "His focus on innovation and client success will ensure Essex continues to deliver transformative solutions in biomedical informatics and health IT."

IONQ Logo

IonQ (NYSE: IONQ), a leader in the quantum computing and networking industry, today announced the completion of its acquisition of substantially all of the assets of Qubitekk, Inc., a prominent quantum networking company. The acquisition brings Qubitekk’s esteemed team, advanced technology, and extensive patent portfolio into IonQ’s operations, solidifying IonQ’s position at the forefront of quantum networking and computing.

Quantum networks are poised to become important infrastructure, with the potential to drive transformative applications in sectors such as defense, finance, and energy. These networks facilitate highly secure communication between multiple quantum nodes using entangled qubits. The technology also enables precise timing synchronization, a transport layer for quantum sensing, and a backbone for distributed quantum computing. With the development and 2022 launch of the EPB Quantum Network in Chattanooga, Tennessee—the first commercially available quantum network in the U.S.—Qubitekk has established itself as a leader in quantum networking.

I MAB Logo

ROCKVILLE, MDJan. 6, 2025 /PRNewswire/ -- I-Mab (NASDAQ: IMAB) (the "Company"), a U.S.-based, global biotech company, focused on the development of precision immuno-oncology agents for the treatment of cancer, today highlighted its strategic outlook for 2025 and a re-prioritization of resources, with a focus on advancing its lead program, givastomig, a CLDN18.2 x 4-1BB bispecific antibody, targeting first-line metastatic gastric cancers, with further potential in other solid tumors.

Bill Tompkins and Rich Square Post 250 x 600 px

In this episode of BioTalk, Bill Tompkins, President and CEO of the Montgomery County Economic Development Corporation (MCEDC), discusses the strategies driving Montgomery County’s position as a leading bioscience hub. Bill highlights MCEDC’s role in reinforcing the region’s standing as the third-largest bioscience cluster in the U.S. and shares insights into the new Institute for Health Computing. He also introduces two new venture funds—the Technology Innovation Fund and the Founders Fund—designed to accelerate innovation and support local entrepreneurs.

Bill outlines MCEDC’s priorities for the upcoming year, emphasizing economic growth, investment opportunities, and fostering collaborations that make Montgomery County a thriving ecosystem for business and life sciences.

Listen now via your favorite podcast platforms:

Apple: https://apple.co/4j6AA0e
Spotify: https://spoti.fi/4iXajSl
Amazon Music: https://amzn.to/3W3Tb3i
YouTube Music: https://bit.ly/3W9hixH
TuneIn: https://bit.ly/427OmtP

Childrens

Kolaleh Eskandanian, chief innovation officer at Children’s National Hospital, said the partnership is meant to address the many challenges with developing devices for children and infants.

Published Jan. 2, 2025 - Elise Reuter, Reporter

A collaboration between a children’s hospital and the Food and Drug Administration aims to address challenges in developing medical devices for children and infants. 

Children’s National Hospital in Washington, D.C., struck a five-year research collaboration with the FDA’s Office of Science and Engineering Laboratories (OSEL) to build regulatory science tools to help evaluate pediatric devices. 

The partners will use de-identified clinical data, multimodal imaging and machine learning to develop open-source tools that can be used to design and test devices more efficiently. 

ArpaHdecarticle

BHI is proud to support ARPA-H through its Partnership Intermediary Agreement (PIA), providing EIR commercialization services to advance groundbreaking technologies. Notably, BaySpec, one of BHI’s clients, was awarded ARPA-H’s first SBIR grant to develop cutting-edge diagnostics. Andy Kilianski, Program Manager at ARPA-H, recaps key 2024 milestones, including AI-driven drug discovery, RNA therapies, and the $204M APECx biologics program. These efforts underscore ARPA-H’s commitment to accelerating biomedical innovation.

Portfolio Views from 2024
Andy Kilianski
Program Manager at ARPA-H

December 30, 2024
Happy Holidays Everyone!

2024 was a BIG year for my team and our investments in the biomedical and biotechnology ecosystem. Our goal is to invest in transformative technology that allows biomedical R&D to be predictive of human outcomes, in ways that are currently impossible. I want to capture some of our key milestones (in semi-chronological order) to highlight the amazing work already underway with our team at the Advanced Research Projects Agency for Health (ARPA-H) . My team and our performers have been incredibly diligent and dedicated to get us to this point. There are a lot of efforts soon-to-be-announced from us as we head into next year, including the kick-off of the CATALYST program mid-2025.

Precigen

Precigen has submitted a Biologics License Application (BLA) to the FDA, seeking priority review for PRGN-2012, which could become the first FDA-approved treatment for adults with recurrent respiratory papillomatosis (RRP)—a rare and chronic disease currently managed through repeated surgeries. PRGN-2012 has received Breakthrough Therapy and Orphan Drug Designations from both the FDA and the European Commission. The application, submitted under an accelerated approval pathway, is backed by Phase 1/2 study data showing over 50% of patients achieved Complete Response and more than 85% experienced fewer surgeries in the year following treatment. PRGN-2012 was also well-tolerated, with no dose-limiting toxicities and no severe treatment-related adverse events.

ACT

National Cancer Institute (NCI) has awarded a $357,000 SBIR grant to Arnold Consultancy & Technology, LLC to develop an open source model marketplace.

MIAMI BEACH, FL, UNITED STATES, December 30, 2024 /EINPresswire.com/ -- New cancer drugs have long been at the forefront of research and debate about rising healthcare expenditure in the United States; researchers and decision-makers rely on evidence to support fair pricing and ensure patient access. HE models support stakeholders in decision-making about the most cost-effective care for the available resources. Annually, stakeholders spend an estimated $1B on health economics and outcomes research (HEOR), much of it to create and recreate health economic (HE) models. Global government bodies use these models to formulate response and reimbursement decisions, aid resource allocation and suggest value-based pricing for new therapies. Sharing models by making their “source code” openly available would mitigate these problems, but prior initiatives to promote model sharing have had limited success in part because model authors fear the loss of their intellectual property and are not paid for their models being deposited.

Jlabs2

BHI is excited to highlight Rachel Rath’s recent LinkedIn Post, where she reflects on her first 90 days as Head of JLABS @ Washington, DC. Rachel, who recently joined the BHI Board of Directors, discusses the Mid-Atlantic’s strengths—including its talent pool, investor activity, and opportunities for deeper collaboration.

We look forward to continuing to work with Rachel and JLABS to drive growth and innovation in the BioHealth Capital Region.

90 Days In: Reflections on an Evolving Life Science Landscape in the Mid-Atlantic

The views and opinions expressed in this article are those of the author.

Time flies when you’re having fun! My first 90 days as Head of JLABS @ Washington, DC (JLABS DC) have been both energizing and eye-opening. While I’ve spent nearly 20 years in the DMV (DC-Maryland-Virginia), been part of Johnson & Johnson and the JLABS team for 5 years, and been based at JLABS DC since the site opened, it’s been fulfilling to move from a global role into a role that allows me to deep-dive into the local ecosystem that I call home. The DMV region and broader Mid-Atlantic region boast incredible strengths, but these first few months in the job have underscored the work that remains to unlock the region’s full potential. Here are three reflections as I recognize the strengths of this region and look at how JLABS DC can continue to help spur the region's trajectory:

Spark logo 8

Children’s National Innovation Ventures is hosting the Symposium on Pediatric Medical Countermeasures (MCMs) and the SPARK for Innovations in Pediatrics Launch and Prize Competition—a premier event under the BARDA Accelerator Network 2.0. This exciting gathering will focus on advancing pediatric-focused MCMs, featuring insightful discussions and a live competition where finalists will pitch their groundbreaking solutions for a chance to secure non-dilutive funding from SPARK.

The event will also include a ribbon-cutting ceremony to officially launch the SPARK Hub, followed by a cocktail reception to celebrate this milestone in pediatric innovation.

BioHealth Innovation (BHI) is a proud partner in this initiative, supporting efforts to drive advancements in pediatric medical countermeasures and foster impactful innovation.

Event Details:

  • Location: Children's National Research and Innovation Campus, 7144 13th Pl NW, Washington, DC 20012
  • Date and Time: Tuesday, January 28, 2025, from 3:00 PM to 7:00 PM

For more information, visit https://lp.constantcontactpages.com/ev/reg/2p7f9t5.

Join us in celebrating this important step toward transforming the future of pediatric healthcare!

PQE Group

Italy, December 23, 2024. PQE Group is proud to announce its most recently-received official recognitions: ISO/IEC 27001 and A Women’s Business Enterprise (WBE) Certifications, which provide additional reasons to recognize PQE Group’s extensive capabilities; the ISO/IEC 27001 provides clients assurance that their information management systems are risk-aware and that PQE Group’s solutions can proactively identify and address weaknesses; the WBE Certification ensures that PQE Group has met the stringent eligibility criteria to be classified as a women-owned enterprise.

WesMooreDecArticle2

DEC 20, ANNAPOLIS, MD — Governor Wes Moore today signed an executive order to strengthen Maryland’s business climate and catalyze more economic growth in the state. The governor signed the order during a visit to the Frederick Hotel and Conference Center project site in Frederick—a public-private development project that is expected to generate $1.5 billion in new private sector spending over the next 25 years, more than 200 jobs, and more than $4 million in state and local tax revenue annually. 

United Therapeutics logo

SILVER SPRING, Md. & RESEARCH TRIANGLE PARK, N.C.--()--United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced the world’s first transplant of a UKidney, which it produced, into a living person on November 25, 2024.

The transplant is the fourth xenotransplant using United Therapeutics’ xeno organs into living humans, following two successful UHeart transplants at the University of Maryland Medicine in 2022 and 2023 and a successful UThymoKidney transplant at NYU Langone Health earlier this year.

pitcharticle

Guillermo Flor -
How to pitch to investors
The basics:
1. Venture Capitalists have an investment thesis they have to follow. If your startup doesn’t fit the investor’s thesis don’t bother pitching

2. Most times you’ll start pitching to associates. Then the associates will have to share the opportunity with the rest of their investment team. The easier you make their job the more chances you have.

3. How you pitch your startup gives out a lot of information about you to investors. Make sure your investment materials are organized, your pitch is concise and to the point and you are likeable.

MayorBowser
Monday, December 16, 2024

(Washington, DC) – Today, Mayor Muriel Bowser launched the DC Venture Capital Program, a new $26 million fund designed to make equity investments for early-stage, DC-based tech companies, prioritizing underrepresented founders. 
 
“Washington, DC is the best place in the nation to launch and grow a business. We know, however, that sometimes talent alone isn’t enough to succeed – and that is why the city has stepped in with a suite of innovative grants to help more entrepreneurs get their fair shot,” said Mayor Bowser. “This DC Venture Capital Program is about investing in people, jobs, and the future of DC’s tech economy.”
 
The DC Venture Capital Fund represents a transformative commitment to DC-based businesses by leveraging public dollars to attract private investment. For every dollar the District invests, private investors are required to contribute at least an equal amount, effectively doubling the total funding available to DC startups to a minimum of $52 million. 
  

Emergent

GAITHERSBURG, Md., Dec. 16, 2024 (GLOBE NEWSWIRE) -- Emergent BioSolutions Inc. (NYSE: EBS) today announced that the Biomedical Advanced Research and Development Authority (BARDA) within the Administration for Strategic Preparedness and Response (ASPR) at the U.S. Department of Health and Human Services has awarded a $50 million option to Emergent’s existing contract (HHSO100201600030C) for the acquisition of CYFENDUS® (Anthrax Vaccine Adsorbed, Adjuvanted).

Novavax Logo

GAITHERSBURG, Md.Dec. 13, 2024 /PRNewswire/ -- Novavax, Inc. (Nasdaq: NVAX), a global company advancing protein-based vaccines with its Matrix-M™ adjuvant, today announced progress in Q4 2024 advancing its corporate growth strategy through its partnership with Sanofi. The Company has achieved a milestone associated with its Phase 2/3 clinical trial for its COVID-19 vaccine in children, triggering the first $50 million milestone payment from Sanofi.

Connected DMV web640

By Ana Lucía Murillo – Staff Reporter, Washington Business Journal Connected DMV has tapped a new chief executive to lead the regionally focused nonprofit.

George Thomas, who has been with Connected DMV since its inception in 2019, is now president and CEO. The group’s founder and only CEO in its history, Stu Solomon, is now listed as executive chairman on the organization’s website. It’s unclear when the transition took place; Solomon was president and CEO as recently as May.

60degrees logo rgb logo

WASHINGTON, Dec. 11, 2024 (GLOBE NEWSWIRE) -- 60 Degrees Pharmaceuticals, Inc. (NASDAQ: SXTP; SXTPW) (60 Degrees Pharmaceuticals or the “Company”), a pharmaceutical company focused on developing new medicines for infectious diseases, announced today it has entered into a clinical trial agreement with Brigham and Women’s Hospital (BWH) in Boston to conduct a double-blind, placebo-controlled study evaluating the safety and efficacy of tafenoquine in combination with standard of care treatment for hospitalized babesiosis patients.

Liquet Logo

RICHMOND, VA, UNITED STATES, December 11, 2024 /EINPresswire.com/ -- Liquet Medical Inc., a pioneering medical device company committed to advancing patient care through innovative technologies, today announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its Versus™ Catheter.

This innovative medical device is set to enhance the treatment of pulmonary artery blood clots by offering real-time pulmonary artery pressure measurements, empowering clinicians to optimize treatment based on individual patient responses. This novel technology enables a new treatment category called “Hemodynamics-Led Thrombolysis (HLT).”

emmes

Emmes®, part of Emmes Group®, a leading specialty tech and AI-enabled global contract research organization (CRO), today announced the appointment of Bryan Patterson to the newly created role of Senior Vice President, Government Business Development & Capture. This strategic expansion of Emmes’ leadership team underscores the company’s commitment to the U.S. Federal Government clinical research efforts, and to exceed expectations, drive innovation, and deliver even greater value.

Novavax Logo

GAITHERSBURG, Md.Dec. 10, 2024 /PRNewswire/ -- Novavax, Inc. (Nasdaq: NVAX), a global company advancing protein-based vaccines with its Matrix-M™ adjuvant, today announced that the first participants have been dosed in its COVID-19-Influenza Combination (CIC) and stand-alone seasonal influenza Phase 3 trial. The trial will evaluate the immunogenicity and safety of the CIC and stand-alone seasonal influenza vaccine candidates compared to Novavax's updated 2024-2025 COVID-19 vaccine (NVX-CoV2705) and a licensed seasonal influenza vaccine comparator in adults aged 65 and older.

Theradaptive

FREDERICK, Md.Dec. 10, 2024 /PRNewswire/ -- Theradaptive, a privately held, clinical stage biologics company developing protein therapeutics for spine, orthopedics, soft tissue repair, and targeted immuno-oncology, announced today that the US Food and Drug Administration (FDA) has approved an expansion to its Phase I/II clinical program, broadening it to include three spinal fusion indications and tripling the number of investigational sites in the US.

The OASIS trial was approved by the FDA earlier this year to assess the safety and efficacy of OsteoAdapt™ SP, Theradaptive's implant with targeted biologics to treat degenerative disc disease, in a transforaminal interbody fusion (TLIF) approach. The recent approval encompasses two other common spinal fusion approaches: anterior lumbar interbody fusion (ALIF) and lateral lumbar interbody fusion (LLIF). The company anticipates enrollment of its first ALIF and LLIF study subjects in early 2025.

BHIEIRs

On December 4th, TEDCO hosted its 10th Entrepreneur Expo in Baltimore, bringing together over 1,000 entrepreneurs, investors, and industry leaders for a day of connection, learning, and celebration. As a premier event in Maryland, the Expo showcased the state’s vibrant entrepreneurial ecosystem through workshops, roundtable discussions, and exhibitions, featuring 95 speakers and 84 companies, including 34 startups. The BioHealth Innovation, Inc. (BHI) team was proud to participate in this dynamic gathering, further strengthening its commitment to fostering growth and commercialization in the BioHealth Capital Region.

NextCure

BELTSVILLE, Md., Dec. 10, 2024 (GLOBE NEWSWIRE) -- NextCure, Inc. (Nasdaq: NXTC), a clinical-stage biopharmaceutical company committed to discovering and developing novel, first-in-class, and best-in-class therapies to treat cancer, today announced that the U.S. Food and Drug Administration (FDA) accepted an Investigational New Drug (IND) application for initiation of a Phase 1 clinical trial to evaluate LNCB74, a B7-H4-targeting antibody-drug conjugate (ADC) as a therapeutic for treating multiple cancers.

Alphyn Biologics LLC

ANNAPOLIS, Md.Dec. 10, 2024 /PRNewswire/ --  Alphyn, a clinical-stage dermatology company developing first-in-class Multi-Target Therapeutics®, announced today that the U.S. Patent and Trademark Office (USPTO) has granted the company a patent covering compositions and methods of use for the drug formulation of Zabalafin Hydrogel (AB-101a) for atopic dermatitis (AD). The patent covers Zabalafin Hydrogel through 2042 and is eligible for listing in the U.S. Food and Drug Administration's (FDA) Orange Book, which provides additional protective benefits once Zabalafin Hydrogel receives FDA approval.

Alithea

Multiplexed, extraction-free, full-length library preparation technology facilitates large-scale RNA sequencing, combining ever more content with high throughput

FREDERICK, Md.Dec. 9, 2024 /PRNewswire-PRWeb/ -- Alithea Genomics, a leader in the field of large-scale RNA sequencing and transcriptomics, announced today the launch of MERCURIUS™ Full-Length DRUG-seq library preparation technology, which combines, for the first time, massive sample multiplexing, an extraction-free workflow and full transcript coverage in a unique RNA-seq workflow. The technology is compatible with both 96- and 384-well plate formats and up-to 384 full-length RNA-seq library preps can be performed in a single tube without RNA isolation.

Gov Wes Moore

ANNAPOLIS, MD – Governor Wes Moore today announced that applications are being accepted for the Maryland Soft Landing Exchange Program, which allows Maryland companies to explore international markets at a reduced cost by connecting them with business incubators and accelerators abroad. The program, administered by the Maryland Department of Commerce, is designed to support companies who are ready to expand their existing export capabilities, and serves as an important enhancement to existing state export assistance.

MBIA

The Maryland Business Innovation Association (MBIA), with support from TEDCO, has announced the launch of the FY25 MBIA Commercialization Innovation Grant (MCIG). Designed to provide strategic funding to Maryland-based innovative companies, the program opens its application window on Tuesday, December 10, at 12pm noon ET. The MCIG offers eligible companies the opportunity to secure funding that supports entrepreneurial advancement and commercialization efforts, driving growth in Maryland’s innovation ecosystem and economy.