GlycoMimetics, Inc. (NASDAQ: GLYC) announced that preclinical data on its novel E-selectin antagonist drug candidate GMI-1271, shared via an oral presentation at the 57th American Society of Hematology (ASH) annual meeting, showed the compound could be used in combination with G-CSF (filgrastim) to mobilize and enrich progenitor T cells known as T memory stem (Tscm) and T central memory (Tcm) cells, which provide improved reconstitution and persistence. The company also announced that the first healthy participant has been treated with an intravenous (IV) formulation of GMI-1271 in a Phase 1, multiple-dose clinical study to evaluate the investigational drug’s ability to mobilize and enrich Tscm or Tcm cells. In addition, the trial will evaluate safety and tolerability of the drug, alone and in combination with filgrastim, a treatment for neutropenia that is approved by the U.S. Food and Drug Administration (FDA).